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A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity File

Choi, Sun-Sil , Kim, Eun Sun , Koh, Minseob , Lee, Soo-Jin , Lim, Donghyun , Yang, Yong Ryoul , Jang, Hyun-Jun , Seo, Kyung-ah , Min, Sang-Hyun , Lee, In Hee , et al

Article Issue Date2014-09 View8

A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis File

Bostroem, Pontus , Wu, Jun , Jedrychowski, Mark P. , Korde, Anisha , Ye, Li , Lo, James C. , Rasbach, Kyle A. , Bostroem, Elisabeth Almer , Choi, Jang Hyun , Long, Jonathan Z. , et al

Article Issue Date2012-01 View6

Alkylation of nucleobases by 2-chloro-N,N-diethylethanamine hydrochloride (CDEAH) sensitizes PARP1-deficient tumors File File

Wie, Minwoo , Khim, Keon Woo , Groehler Iv, Arnold S , Heo, Soomin , Woo, Junhyeok , Son, Kook , Lee, Eun A , Ra, Jae Sun , Hong, Sung You , Scharer, Orlando D. , et al

Article Issue Date2023-09 View33

Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase File File

Kang, Yujin , Han, Ye Gi , Khim, Keon Woo , Choi, Woo Gyun , Ju, Min Kyung , Park, Kibeom , Shin, Kyeong Jin , Chae, Young Chan , Choi, Jang Hyun , Kim, Hongtae , et al

Article Issue Date2023-08 View18

Alternation of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase

Kang, Yujin , Han, Ye Gi , Khim, Keon Woo , Choi, Woo Gyun , Ju, Min Kyung , Park, Kibeom , Choi, Jang Hyun , Kim, Hongtae , Lee, Ja Yil

Conference Paper Issue Date2022-04-20 View6

Alternation of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase

Kang, Yujin , Han, Ye Gi , Khim, Keon Woo , Choi, Jang Hyun , Kim, Hongtae , Lee, Ja Yil

Conference Paper Issue Date2024-03-12 View83

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPAR gamma by Cdk5 File

Choi, Jang Hyun , Banks, Alexander S. , Estall, Jennifer L. , Kajimura, Shingo , Bostroem, Pontus , Laznik, Dina , Ruas, Jorge L. , Chalmers, Michael J. , Kamenecka, Theodore M. , Blueher, Matthias , et al

Article Issue Date2010-07 View5

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARg by cdk5

Choi, Jang Hyun , Banks, AS , Estall, JL , Kajimura, S , Bostrom, P , Laznik, D , Ruas, JL , Chalmers, MJ , Kamenecka, TM , Bluher, M , et al

Conference Paper Issue Date2011-02-01 View14

Antidiabetic actions of a non-agonist PPAR gamma ligand blocking Cdk5-mediated phosphorylation File

Choi, Jang Hyun , Banks, Alexander S. , Kamenecka, Theodore M. , Busby, Scott A. , Chalmers, Michael J. , Kumar, Naresh , Kuruvilla, Dana S. , Shin, Youseung , He, Yuanjun , Bruning, John B. , et al

Article Issue Date2011-09 View6

B-cell translocation gene-2 increases hepatic gluconeogenesis via induction of CREB File

Hwang, Seung-Lark , Kwon, Okyun , Lee, Soo Jin , Roh, Seong-Soo , Kim, Yong Deuk , Choi, Jang Hyun

Article Issue Date2012-11 View15

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human File

Wu, Jun , Bostrom, Pontus , Sparks, Lauren M. , Ye, Li , Choi, Jang Hyun , Giang, An-Hoa , Khandekar, Melin , Virtanen, Kirsi A. , Nuutila, Pirjo , Schaart, Gert , et al

Article Issue Date2012-07 View12

Broussonetia papyrifera Root Bark Extract Exhibits Anti-inflammatory Effects on Adipose Tissue and Improves Insulin Sensitivity Potentially Via AMPK Activation File File

Lee, Jae Min , Choi, Sun Sil , Park, Mi Hyeon , Jang, Hyunduk , Lee, Yo Han , Khim, Keon Woo , Oh, Sei Ryang , Park, Jiyoung , Ryu, Hyung Won , Choi, Jang Hyun

Article Issue Date2020-03 View20

C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle Atrophy File

Koh, Ara , Lee, Mi Nam , Yang, Yong Ryoul , Jeong, Heeyoon , Ghim, Jaewang , Noh, Jeongeun , Kim, Jaeyoon , Ryu, Dongryeol , Park, Sehoon , Song, Parkyong , et al

Article Issue Date2013-04 View7

Cbl competitively inhibits epidermal growth factor-induced activation of phospholipase C-gamma 1

Choi, Jang Hyun , Bae, SS , Park, JB , Ha, SH , Song, H , Kim, JH , Cocco, L , Ryu, SH , Suh, Pann-Ghill

Article Issue Date2003-04 View5

Characterization of physiological roles of Flightless-1 in cancer progression

최장현 , 이요한

Conference Paper Issue Date2017-07-05 View3

Cleavage of focal adhesion kinase is an early marker and modulator of oxidative stress-induced apoptosis File

Mian, Md. Firoz , Kang, Changkeun , Lee, Seunghwan , Choi, Jang Hyun , Bae, Sun Sik , Kim, Sun-Hee , Kim, Yun-Hee , Ryu, Sung Ho , Suh, Pann-Ghill , Kim, Jong-Shu , et al

Article Issue Date2008-01 View7

COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease File

Lee, Changu , Kim, Min , Lee, Jun Ho , Oh, Jiyoung , Shin, Hyun-Hee , Lee, Sang Min , Scherer, Philipp , Kwon, H. Moo , Choi, Jang Hyun , Park, Jiyoung

Article Issue Date2019-01 View22

Diverse cellular and physiological roles of phospholipase C-γ1 File

Yang, Yong Ryoul , Choi, Jang Hyun , Chang, Jong-Soo , Kwon, H. Moo , Jang, Hyun-Jun , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2012-01 View10

Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling File

Yang, Yong Ryoul , Kim, Dae Hyun , Seo, Young-Kyo , Park, Dohyun , Jang, Hyun-Jun , Choi, Soo Youn , Lee, Yong Hwa , Lee, Gyun Hui , Nakajima, Kazuki , Taniguchi, Naoyuki , et al

Article Issue Date2015-05 View8

Fibroblast Growth Factor-21 Regulates PPAR gamma Activity and the Antidiabetic Actions of Thiazolidinediones File

Dutchak, Paul A. , Katafuchi, Takeshi , Bookout, Angie L. , Choi, Jang Hyun , Yu, Ruth T. , Mangelsdorf, David J. , Kliewer, Steven A.

Article Issue Date2012-02 View4

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis File File

Choi, Sun Sil , Lee, Sang Kwon , Kim, Joong Kwan , Park, Hye-Kyung , Lee, Eujin , Jang, Jinho , Lee, Yo Han , Khim, Keon Woo , Hyun, Ji-Min , Eom, Hye-jin , et al

Article Issue Date2020-06 View26

Flightless-1, a novel transcriptional modulator of PPARγ through competing with RXRα File

Choi, Jin Sil , Choi, Sun-Sil , Kim, Eun Sun , Seo, Young Kyo , Seo, Jeong Kon , Kim, Eung-Kyu , Suh, Pann-Ghill , Choi, Jang Hyun

Article Issue Date2015-03 View8

Flightless-I Controls Fat Storage in Drosophila File File

Park, Jung-Eun , Lee, Eun Ji , Kim, Jung Kwan , Song, Youngsup , Choi, Jang Hyun , Kang, Min-Ji

Article Issue Date2018-06 View12

Forebrain-specific ablation of phospholipase C gamma 1 causes manic-like behavior File

Yang, YR , Jung, JH , Kim, SJ , Hamada, K , Suzuki, A , Kim, HJ , Lee, JH , Kwon, OB , Lee, YK , Kim, J , et al

Article Issue Date2017-10 View14

Ginkgolic acid stimulates adipose tissue thermogenesis by targeting GPR120/PPARγ axis

Khim, Keon Woo , Choi, Jang Hyun

Conference Paper Issue Date2023-01-17 View8

Gleevec improves insulin sensitivity and promotes browning.

Choi, Jang Hyun

Conference Paper Issue Date2015-04-11 View9

Gleevec promotes browning of white adipose tissue

Choi, Jang Hyun

Conference Paper Issue Date2015-12-05 View5

Gleevec regulates insulin sensitivity

Choi, Jang Hyun

Conference Paper Issue Date2016-04-01 View1

Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCer File

Jang, Hyun-Jun , Lim, Seyoung , Kim, Jung-Min , Yoon, Sora , Lee, Chae Young , Hwang, Hyeon-Jeong , Shim, Jeong Woo , Shin, Kyeong Jin , Kim, Hye Yun , Park, Kwang Il , et al

Article Issue Date2020-01 View20

Grb2 negatively regulates epidermal growth factor-induced phospholipase C-gamma 1 activity through the direct interaction with tyrosine-phosphorylated phospholipase C-gamma 1 File

Choi, Jang Hyun , Hong, WP , Yun, S , Kim, HS , Lee, JR , Park, JB , Bae, YS , Ryu, SH , Suh, Pann-Ghill

Article Issue Date2005-10 View6

Haloperidol induces calcium ion influx via L-type calcium channels in hippocampal HN33 cells and renders the neurons more susceptible to oxidative stress

Kim, Hyeon Soo , Yumkham, Sanatombi , Choi, Jang Hyun , Kim, Eung-Kyun , Kim, Yong Sik , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2006-08 View8

Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA File

Lee, Yo Han , Jang, Hyun-Jun , Kim, Sounkou , Choi, Sun Sil , Khim, Keon Woo , Eom, Hye-Jin , Hyun, Jimin , Shin, Kyeong Jin , Chae, Young Chan , Kim, Hongtae , et al

Article Issue Date2021-12 View26

Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA

Lee, Yohan , Choi, Jang Hyun

Conference Paper Issue Date2023-01-17 View8

Hepatic MIR93 promotes metabolic dysfunction associated fatty liver disease by suppressing SIRT1

Lee, Yo Han , Choi, Jang Hyun

Conference Paper Issue Date2024-03-05 View22

How to make the novel anti-diabetic PPARg ligands

Choi, Jang Hyun

Conference Paper Issue Date2012-04-26 View4

HVEM signaling in monocytes is mediated by intracellular calcium mobilization

Heo, Sook-Kyoung , Yoon, Min-A , Lee, Sang-Chul , Ju, Seong-A , Choi, Jang Hyun , Suh, Pann-Ghill , Kwon, Byoung S. , Kim, Byung-Sam

Article Issue Date2007-11 View6

Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors File

Malapaka, Raghu R. V. , Khoo, SokKean , Zhang, Jifeng , Choi, Jang Hyun , Zhou, X. Edward , Xu, Yong , Gong, Yinhan , Li, Jun , Yong, Eu-Leong , Chalmers, Michael J. , et al

Article Issue Date2012-01 View6

Identification of a new functional target of haloperidol metabolite: implications for a receptor-independent role of 3-(4-fluorobenzoyl) propionic acid File

Kim, Hyeon Soo , Song, Minseok , Yumkham, Sanatombi , Choi, Jang Hyun , Lee, Taehoon , Kwon, Joseph , Lee, Sung Jae , Kim, Jong-In , Lee, Kang-Woo , Han, Pyung-Lim , et al

Article Issue Date2006-10 View7

In vitro assay of neurofilament light chain self-assembly using truncated mutants File

Kim, Sung-Kuk , Cho, Sang-Min , Lee, In-Bum , Lee, Young Han , Kang, Jung Hoon , Choi, Jang Hyun , Suh, Pann-Ghill , Chang, Jong-Soo

Article Issue Date2007-04 View4

Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppression File

Hua, Tuyen N.M. , Kim, Min-Kyu , Vo, Vu T.A. , Choi, Jong-Whan , Choi, Jang Hyun , Kim, Hyun-Won , Cha, Seung-Kuy , Park, Kyu-Sang , Jeong, Yangsik

Article Issue Date2019-03 View16

Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise File

Moon, Hyo Youl , Kim, Se Hyun , Yang, Yong Ryoul , Song, Parkyong , Yu, Hyun Sook , Park, Hong Geun , Hwang, Onyou , Lee-Kwon, Whaseon , Seo, Jeong Kon , Hwang, Daehee , et al

Article Issue Date2012-08 View9

Mechanistic Elucidation Guided by Covalent Inhibitors for the Development of Anti-diabetic PPARγ Ligands File File

Bae, Hwan , Jang, Jun Young , Choi, Sun-Sil , Lee, Jae-Jin , Kim, Heejun , Jo, Ala , Lee, Kong-Joo , Choi, Jang Hyun , Suh, Se Won , Park, Seung Bum

Article Issue Date2016-08 View14

Metabolic regulation by PPARg phosphorylation

Choi, Jang Hyun

Conference Paper Issue Date2019-10-11 View7

Metabolic regulation by PPARg phosphorylation

Choi, Jang Hyun

Conference Paper Issue Date2020-06-19 View7

miRNA as a key regulator in MAFLD

Choi, Jang Hyun

Conference Paper Issue Date2023-11-28 View13

N-Acetylfarnesylcysteine Is a Novel Class of Peroxisome Proliferator-activated Receptor gamma Ligand with Partial and Full Agonist Activity in Vitro and in Vivo File

Bhalla, Kavita , Hwang, Bor Jang , Choi, Jang Hyun , Dewi, Ruby , Ou, Lihui , Mclenithan, John , Twaddel, William , Pozharski, Edwin , Stock, Jeffry , Girnum, Geoffrey D.

Article Issue Date2011-12 View7

Neurotensin enhances nitric oxide generation via the JAK2-STAT1 pathway in murine macrophage Raw264.7 cells during costimulation with LPS and IFN gamma File

Kim, HS , YumkhaM, S , Choi, Jang Hyun , Lee, SH , Kim, TH , Ryu, SH , Suh, Pann-Ghill

Article Issue Date2006-06 View8

Non-agonist PPARg ligands and energy metabolism

Choi, Jang Hyun

Conference Paper Issue Date2016-05-13 View2

Noncanonical agonist PPAR gamma ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy File

Khandekar, Melin J. , Banks, Alexander S. , Laznik-Bogoslavski, Dina , White, James P. , Choi, Jang Hyun , Kazak, Lawrence , Lo, James C. , Cohen, Paul , Wong, Kwok-Kin , Kamenecka, Theodore M. , et al

Article Issue Date2018-01 View3

Novel insights into muscle and adipose tissue

Choi, Jang Hyun

Conference Paper Issue Date2022-05-14 View6

Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivity File

Choi, Sunsil , Jung, Ji-Eun , Yang, Yong Ryoul , Kim, Eun-Sun , Jang, Hyun-Jun , Kim, Eung-Kyun , Kim, Il Shin , Lee, Joo-Young , Kim, Joong Kwan , Seo, Jeong Kon , et al

Article Issue Date2015-12 View4

NSMF promotes the replication stress-induced DNA damage response for genome maintenance File

Ju, Min Kyung , Shin, Kyeong Jin , Lee, Joo Rak , Khim, Keon Woo , Lee, Eun A , Ra, Jae Sun , Kim, Byung-Gyu , Jo, Han-seul , Yoon, Jong Hyuk , Kim, Tae Moon , et al

Article Issue Date2021-06 View18

O-GlcNAcase is essential for embryonic development and maintenance of genomic stability File File

Yang, Yong Ryoul , Song, Minseok , Lee, Ho , Jeon, Yoon , Choi, Eun-Jeong , Jang, Hyun-Jun , Moon, Hyo Youl , Byun, Ha-Young , Kim, Eung-Kyun , Kim, Dae Hyun , et al

Article Issue Date2012-06 View9

Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice. File

Yang, Yong Ryoul , Jang, Hyun-Jun , Choi, Sun-Sil , Lee, Yong Hwa , Lee, Gyun Hul , Seo, Young-Kyo , Choi, Jang Hyun , Park, Dohyun , Koh, Ara , Kim, Il Shin , et al

Article Issue Date2015-12 View5

OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ mice File File

Yang, Yongryoul , Jang H.J. , Yoon, Sunyoung , Lee, Yonghwa , Nam, Dougu , Kim, I.S. , Lee, Heeseok , Kim, Hyun , Choi, Jang Hyun , Kang, Byoung Heon , et al

Article Issue Date2014-07 View17

On/Off-regulation of phospholipase C-gamma 1-mediated signal transduction File

Choi, Jang Hyun , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2007 View5

PDZ Domain-containing 1 (PDZK1) Protein Regulates Phospholipase C-beta 3 (PLC-beta 3)-specific Activation of Somatostatin by Forming a Ternary Complex with PLC-beta 3 and Somatostatin Receptors File

Kim, Jung Kuk , Kwon, Ohman , Kim, Jinho , Kim, Eung-Kyun , Park, Hye Kyung , Lee, Ji Eun , Kim, Kyung Lock , Choi, Jung Woong , Lim, Seyoung , Seok, Heon , et al

Article Issue Date2012-06 View8

Phenotypic screening to identify small-molecule enhancers for glucose uptake: Target identification and rational optimization of their efficacy File

Koh, Minseob , Park, Jongmin , Koo, Ja Young , Lim, Donghyun , Cha, Mi Young , Jo, Ala , Choi, Jang Hyun , Park, Seung Bum

Article Issue Date2014-05 View8

Phospholipase C gamma 1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B File

Choi, Jang Hyun , Kim, Hyeon Soo , Kim, Sun-Hee , Yang, Yong Ryoul , Bae, Yun Soo , Chang, Jong-Soo , Kwon, H. Moo , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2006-12 View7

Phospholipase C-epsilon augments epidermal growth factor-dependent cell growth by inhibiting epidermal growth factor receptor down-regulation File

Yun, Sanguk , Hong, Won-Pyo , Choi, Jang Hyun , Yi, Kye Sook , Chae, Suhn-Kee , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2008-01 View5

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