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Alkaline phosphatase responsive disassembly and intracellular polymerization for the supramolecular senolytics with high selectivity

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2024-05-28 View51

Alkaline phosphatase responsive disulfide formation for transforming into fiber structure inside mitochondria of senescent cells

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2023-10-26 View70

Array-based Protein Sensing using an Aggregation Induced Emission Light-Up Probe

Choi, Huyeon , Kim, Sangpil , Lee, Seungho , Kim, Chaekyu , Ryu, Ja-Hyoung

Conference Paper Issue Date2018-04-19 View81

Array-Based Protein Sensing Using an Aggregation-Induced Emission (AIE) Light-Up Probe File File

Choi, Huyeon , Kim, Sangpil , Lee, Seungho , Kim, Chaekyu , Ryu, Ja-Hyoung

Article Issue Date2018-08 View165

CAIX-Targeting Self-Assembly of Peptide Amphiphile in Low Therapeutic Range Inducing Cellular Apoptosis

Kim, Dohyun , Kim, Sangpil , Choi, Huyeon , Ryu, Ja-Hyoung

Conference Paper Issue Date2021-10-15 View86

Clearance of senescent cells for improving tissue regeneration

Kim, Sangpil , Choi,Huyeon , Chung,Hyewon , Ryu, Ja-Hyoung , Kim, Chaekyu

Conference Paper Issue Date2018-05-25 View71

Detection and Identification of Proteins based on Aggregation Induced Emission (AIE) Properties

Choi, Huyeon , Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2016-10-04 View60

Disulfide-Mediated siRNA Delivery System based on in situ Polymerization for Synergistic Antitumor Therapy

Park, Gaeun , Kim, Sangpil , Choi, Eunshil , Ryu, Ja-Hyoung

Conference Paper Issue Date2022-10-20 View76

Drug resistance-free cytotoxic nanodrugs in composites for cancer therapy File

Jana, Batakrishna , Kim, Dongkap , Choi, Huyeon , Kim, Minsoo , Kim, Kibeom , Kim, Sangpil , Jin, Seongeon , Park, Myoung-Hwan , Lee, Kwan Hyi , Yoon, Cheolho , et al

Article Issue Date2021-04 View114

Drug-Loaded Nanogel for Efficient Orchestration of Cell Death Pathways by Intramitochondrial Disulfide Polymerization File

Choi, Eun Seong , Kim, Sangpil , Kim, Dohyun , Choi, Eunshil , Ryu, Ja-Hyoung

Article Issue Date2024-04 View167

Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting Drug File

Hu, Sung , Ferraro, Mariarosaria , Thomas, Ajesh P. , Chung, Jeong Min , Yoon, Nam Gu , Seol, Ji-Hoon , Kim, Sangpil , Kim, Han-Ul , An, Mi Young , Ok, Haewon , et al

Article Issue Date2020-03 View161

Effects of national forest inventory plot location error on forest carbon stock estimation using k-nearest neighbor algorithm File

Jung, Jaehoon , Kim, Sangpil , Hong, Sungchul , Kim, Kyoungmin , Kim, Eunsook , Im, Jungho , Heo, Joon

Article Issue Date2013-07 View145

Endoplasmic Reticulum Targeting Unfolded Protein Binding Disulfide Polymerization Strategy for Cancer Treatment

Sajid, Hasan , Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2024-08-28 View67

Enzyme-Instructed Intramitochondrial Polymerization for Enhanced Anticancer Treatment without the Development of Drug-Resistance

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2024-04-25 View112

Enzyme-Instructed Intramitochondrial Polymerization for Enhanced Anticancer Treatment without the Development of Drug-Resistance File

Kim, Sangpil , Lee, Yeji , Seu, Min-Seok , Sim, Youjung , Ryu, Ja-Hyoung

Article Issue Date2024-09 View94

Enzyme-responsive disulfide polymerization inside cells for selective removal of aging cells

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2022-10-20 View58

Enzyme-Responsive Nanostructure Transformation for Targeted Mitochondrial Senolytics

Kim, Sangpil , Lee, Jaeeun , Cho, Yumi , Park, Hyun-Seo , Oh, Seung Hak , Kim, Jiye , Kim, Dohyun , Sim, Youjung , Seu, Min-Seok , Kim, Chaekyu , et al

Conference Paper Issue Date2025-04-16 View3

Enzyme-Responsive Nanostructure Transformation for Targeted Mitochondrial Senolytics

Kim, Sangpil , Lee, Jaeeun , Cho, Yumi , Park, Hyun-Seo , Oh, Seung Hak , Kim, Jiye , Kim, Dohyun , Sim, Youjung , Seu, Min-Seok , Kim, Chaekyu , et al

Conference Paper Issue Date2025-01-10 View12

In situ Polymerization via Bioorthogonal Condensation in Mitochondria Controls Cell Fate

Park, Gaeun , Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2022-04-14 View81

Intra-Lysosomal Assembly of Peptides for Highly Selective Cancer Cell Death and Overcoming of Drug Resistance

Jana, Batakrishna , Jin, Sungeon , Kim, Dohyun , Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2022-10-20 View98

Intra-Lysosomal Peptide Assembly for the High Selectivity Index against Cancer File

Jana, Batakrishna , Jin, Seongeon , Go, Eun Min , Cho, Yumi , Kim, Dohyun , Kim, Sangpil , Kwak, Sang Kyu , Ryu, Ja-Hyoung

Article Issue Date2023-08 View156

Intra-mitochondrial biomineralization for inducing apoptosis of cancer cells File File

Kim, Sangpil , Palanikumar, L. , Choi, Huyeong , Jeena, M.T. , Kim, Chaekyu , Ryu, Ja-Hyoung

Article Issue Date2018-03 View98

Intra-Mitochondrial Biomineralization for Inducing Apoptosis of Cancer Cells

Kim, Sangpil , Ryu, Ja-Hyoung , Kim, Chaekyu , Choi, Huyeon

Conference Paper Issue Date2018-04-19 View67

Intra-Mitochondrial Biomineralization for inducing apoptosis of cancer cells

Kim, Sangpil , Loganathan, Palanikumar , Choi, Huyeon , Jeena, MT , Kim, Chaekyu , Ryu, Ja-Hyoung

Conference Paper Issue Date2017-10-20 View61

Intra-Mitochondrial Biomineralization for inducing apoptosis of cancer cells

Kim, Sangpil , L.Palanikumar , Choi, Huyeon , Jeena, M.T. , Kim, Chaekyu , Ryu, Ja-Hyoung

Conference Paper Issue Date2017-08-20 View48

Intra-mitochondrial Disulfide Polymerization Controls Cancer Cell Necroptosis

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2020-06-07 View66

Intra-mitochondrial Polymerization Induced Self-Assembly for Regulating Cellular Fate File

Kim, Sangpil

Thesis Issue Date2022-02 View66

Intra-Mitochondrial Polymerization-induced Self-Assembly using Dynamic Disulfide Bond for Anti-Cancer Treatment

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2019-04-18 View76

Intra-mitochondrial reaction for cancer cell imaging and anti-cancer therapy by aggregation-induced emission File File

Kim, Sangpil , Kim, Juhee , Jana, Batakrishna , Ryu, Ja-Hyoung

Article Issue Date2020-12 View116

Intracellular Chemical Reaction-Induced Self-Assembly for the Construction of Artificial Architecture and its Functions File

Kim, Sangpil , Park, Gaeun , Kim, Dohyun , Md. Sajid Hasan , Lim, Chaelyeong , Seu, Min-Seok , Ryu, Ja-Hyoung

Article Issue Date2024-04 View67

Intracellular Self Assembly of Small Probe through Condensation Reacting for Imaging Mitochondria in Cancer Cell

Kim, Sangpil , Palanikumar, L. , Choi, Huyeon , Ryu, Ja-Hyoung

Conference Paper Issue Date2016-10-04 View65

Intramitochondrial co-assembly between ATP and nucleopeptides induces cancer cell apoptosis File File

Choi, Huyeon , Park, Gaeun , Shin, Eunhye , Shin, Seon Woo , Jana, Batakrishna , Jin, Seongeon , Kim, Sangpil , Wang, Huaimin , Kwak, Sang Kyu , Xu, Bing , et al

Article Issue Date2022-04 View167

Intramitochondrial Disulfide Polymerization Controls Cancer Cell Fate File

Kim, Sangpil , Jana, Batakrishna , Go, Eun Min , Lee, Ji Eun , Jin, Seongeon , An, Eun-Koung , Hwang, Juyoung , Sim, Youjung , Son, Sehee , Kim, Dohyun , et al

Article Issue Date2021-09 View130

Intramitochondrial polymerization induced self-assembly for regulating cellular fate

Kim, Sangpil , Kim, Dohyun , Chae, Jae-Byoung , Chung, Hyewon , Ryu, Ja-Hyoung

Conference Paper Issue Date2023-04-27 View73

Intramitochondrial Polymerization-induced Self-Assembly (Mito-PISA) using Covalent Bond Controls Cancer Cell Necrosis

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2019-10-10 View87

Intramitochondrial Polymerization-induced Self-Assembly (Mito-PISA) Using Covalent Bond Controls Cancer Cell Necrosis

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2020-10-08 View54

Light driven disulfide polymerization with aggregation induced emission property inside mitochondria

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2022-03-25 View60

Mitochondria Targeting (Supramolecular) Polymerization for New Cancer Therapy

Jeena, MT , Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2018-08-02 View50

Mitochondria targeting self-assembly derived from drug-loaded polymeric nanogel for combination therapy

Choi, Eun Seong , Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2022-09-29 View58

Mitochondrial Heat Shock Protein-Guided Photodynamic Therapy File

Thomas, Ajesh P. , Lee, An-Jung , Palanikumar, L , Jana, Batakrishna , Kim, Kibeom , Kim, Sangpil , Ok, Haewon , Seol, Jihoon , Kim, Dongseok , Kang, Byoung Heon , et al

Article Issue Date2019-10 View176

Mitochondrial Membrane Disrupting Molecules for Selective Killing of Senescent Cells File

Jana, Batakrishna , Kim, Sangpil , Chae, Jae-Byoung , Chung, Hyewon , Kim, Chaekyu , Ryu, Ja-Hyoung

Article Issue Date2021-12 View138

Multivalent Interaction using disulfide formation-induced Self-Assembly inside Mitochondria for Senolytic Effect

Kim, Sangpil , Kim, Dohyun , Jana, Batakrishna , Ryu, Ja-Hyoung

Conference Paper Issue Date2022-04-15 View80

Multivalent Interaction using Polymerization-induced Self-Assembly inside Mitochondria for senolytic effect

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2021-10-22 View53

New Approach for Cancer Therapy with High Selectivity via Enzyme-Targeting Organelle Localized Self-Assembly Inside Lysosome

Kim, Dohyun , Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2021-04-08 View64

Organelle Localization-Induced Bio-orthogonal Polymerization (OLIBOP) for Photostable Super-Resolution Live-cell Imaging

Park, Gaeun , Kim, Sangpil , Kim, Dohyun , Hwang, Injun , Ryu, Ja-Hyoung

Conference Paper Issue Date2025-08-26 View4

Organelle Targeting Self-Assembled Fluorescent Probe for Anticancer Treatment File File

Hasan, Md Sajid , Kim, Sangpil , Lim, Chaelyeong , Lee, Jaeeun , Seu, Min-Seok , Ryu, Ja-Hyoung

Article Issue Date2024-07 View119

Overcoming low selectivity with CAIX-targeting Amphiphilic Peptide inducing cell death

Kim, Dohyun , Kim, Sangpil , Choi, Huyeon , Park, Gaeun , Ryu, Ja-Hyoung

Conference Paper Issue Date2021-10-22 View66

Photo-regulated Assembly-Disassembly Dynamics for Interfering Organelle Membrane Integrity

Kim, Dohyun , Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2025-10-24 View2

Photoregulated Assembly-Disassembly Dynamics of Interfering with Organelle Membrane Integrity File

Kim, Sangpil , Kim, Dohyun , Jo, Youngji , Son, Sehee , Sim, Youjung , Ok, Haewon , Lee, Jaeeun , Ryu, Ja-Hyoung

Article Issue Date2025-09 View21

Polymerization Induced Self-Assembly inside mitochondria for cancer therapy

Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2019-12-09 View56

Quaternary ammonium-based mitochondria targeting anticancer agents with high water solubility File

Kim, Sangpil , Yoon, Nam Gu , Jana, Batakrishna , Kang, Byoung Heon , Ryu, Ja-Hyoung

Article Issue Date2022-03 View146

Recent progress in mitochondria-targeted drug and drug-free agents for cancer therapy File File

Jeena, M.T. , Kim, Sangpil , Jin, Seongeon , Ryu, Ja-Hyoung

Article Issue Date2020-01 View150

Redox-responsive and surface protein-retractive mesoporous organosilica nanoparticles for enhanced cancer therapy

Yang, Gyeongseok , Kim, Sangpil , Oh, Jun Yong , Jin, Seongeon , Choi, Eunshil , Ryu, Ja-Hyoung

Conference Paper Issue Date2023-09-21 View109

Regulating stem cells and senescent cells for regenerative medicine

Choi, Huyeon , Kim, Sangpil , Chung, Hyewon , Ryu, Ja-Hyoung , Kim, Chaekyu

Conference Paper Issue Date2018-05-26 View52

Self-assembly inside cellular organelles: Aspects of functions and various strategies for cancer therapy File File

Kim, Sangpil , Choi, Huyeon , Jin, Seongeon , Son, Sehee , Lee, Yeji , Kim, Kibeom , Ryu, Ja-Hyoung

Article Issue Date2023-02 View95

Self-assembly of Mitochondria-targeted Photosensitizer to Increase Photostability and Overcome Hypoxia in Photodynamic Therapy

Jana, Batakrishna , Thomas, Ajesh P. , Kim, Sangpil , Ryu, Ja-Hyoung

Conference Paper Issue Date2019-12-09 View58

Self‐Assembly of Mitochondria‐Targeted Photosensitizer to Increase Photostability and Photodynamic Therapeutic Efficacy in Hypoxia File

Jana, Batakrishna , Thomas, Ajesh P. , Kim, Sangpil , Lee, In Seong , Choi, Huyeon , Jin, Seongeon , Park, Soo Ah , Min, Seung Kyu , Kim, Chaekyu , Ryu, Ja-Hyoung

Article Issue Date2020-08 View104

Sensing Proteins using Light up – Aggregation Induced Emission (AIE)

Choi, Huyeon , Kim, Sangpil , Lee, Seungho , Kim, Chaekyu , Ryu, Ja-Hyoung

Conference Paper Issue Date2017-08-20 View64

Sensing Proteins using Light up – Aggregation Induced Emission (AIE)

Choi, Huyeon , Kim, Sangpil , Lee, Seungho , Kim, Chaekyu , Ryu, Ja-Hyoung

Conference Paper Issue Date2017-03-31 View75

Sequential Enzyme-Responsive Supramolecular System for Selective Mitochondrial Disruption in Senescent Cells

Lee, Jaeeun , Kim, Sangpil , Kim, Dohyun , Sim, Youjung , Seu, Min-Seok , Ryu, Ja-Hyoung

Conference Paper Issue Date2025-08-26 View2

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