Scholarworks@UNIST: Browsing Repository

A chemical tool for blue light-inducible proximity photo-crosslinking in live cells File

Mishra, Pratyush Kumar , Kang, Myeong-Gyun , Lee, Hakbong , Kim, Seungjoon , Choi, Subin , Sharma, Nirmali , Park, Cheol-Min , Ko, Jaewon , Lee, Changwook , Seo, Jeong Kon , et al

Article Issue Date2022-01 View23

A novel TRAP1 inhibitor, UB-010 potently inactivates the mitochondrial chaperoneby interacting with the client binding site.

Yoon, Nam Gu , Hu, Sung , Kim. So-Yeon , Lee, Changwook , Kang, Byoung Heon

Conference Paper Issue Date2020-10-08 View8

Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance File

Sim, Hyo Jung , Cho, Chanmi , Kim, Ha Eun , Hong, Ju Yeon , Song, Eun Kyung , Kwon, Keun Yeong , Jang, Dong Gil , Kim, Seok-Jung , Lee, Changwook , Lee, Hyun-Shik , et al

Article Issue Date2022-01 View14

Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy File File

Kwon, Jiwoong , Park, Jong-Seok , Kang, Minsu , Choi, Soobin , Park, Jumi , Kim, Gyeong Tae , Lee, Changwook , Cha, Sangwon , Rhee, Hyun-Woo , Shim, Sang-Hee

Article Issue Date2020-01 View11

Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex

Jeong, Hanbin , Park, Jumi , Lee, Changwook

Conference Paper Issue Date2017-10-18 View4

Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex File

Jeong, Hanbin , Park, Jumi , Lee, Changwook

Article Issue Date2016-12 View9

Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway File File

Jeong, Hanbin , Sim, Hyo Jung , Song, Eun Kyung , Lee, Hakbong , Ha, Sung Chul , Jun, Youngsoo , Park, Tae Joo , Lee, Changwook

Article Issue Date2016-02 View8

Crystal Structures of Mmm1 and Mdm12-Mmm1 Reveal Mechanistic Insight into Phospholipid Trafficking at ER-Mitochondria Contact Sites

Jeong, Hanbin , Park, Jumi , Jun, Youngsoo , Lee, Changwook

Conference Paper Issue Date2018-01-04 View7

Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites File

Jeong, Hanbin , Park, Jumi , Jun, Youngsoo , Lee, Changwook

Article Issue Date2017-11 View13

Crystallization and preliminary X-ray diffraction analysis of the Sel1-like repeats of SEL1L File

Jeong, Hanbin , Lee, Hakbong , Lee, Changwook

Article Issue Date2014-12 View9

Crystallization and preliminary X-ray diffraction analysis of Trap1 complexed with Hsp90 inhibitors File

Kang, Byoung Heon , Jeong, Hanbin , Lee, Changwook

Article Issue Date2014-12 View9

Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity File

Yang, Sujae , Yoon, Nam Gu , Kim, Dongyoung , Park, Eunsun , Kim, So-Yeon , Lee, Ji Hoon , Lee, Changwook , Kang, Byoung Heon , Kang, Soosung

Article Issue Date2021-07 View22

Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human Trap1

Lee, Changwook

Conference Paper Issue Date2015-09-16 View6

Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1 File

Lee, Changwook , Park, Hye-Kyung , Jeong, Hanbin , Lim, Jaehwa , Lee, An-Jung , Cheon, Keun Young , Kim, Chul-Su , Thomas, Ajesh P. , Bae, Boram , Kim, Nam Doo , et al

Article Issue Date2015-04 View18

Development of Hsp90 family protein inhibitors

Park, Hye-Kyung , Ko, Eunhwa , Lee, Geumwoo , Lee, Ji-Eun , Lee, Sang Kwang , Jeong, Hanbin , Lee, An-Jung , Im, Jin Young , Kim, Seong Heon , Lee, Changwook , et al

Conference Paper Issue Date2016-12-09 View6

Development of mitochondria-targeted Hsp90 inhibitor as a anti-cancer drug

Park, Hye-Jyung , Ko, Eunhwa , Lee, Gemwoo , Lee, Ji-Eun , Lee, Sang Kwang , Jeong, Hanbin , Lee, An-Jung , Im, Jing Young , Hu, Sung , Kim, Seong Heon , et al

Conference Paper Issue Date2016-11-25 View3

Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models File

Kim, Darong , Kim, So-Yeon , Kim, Dongyoung , Yoon, Nam Gu , Yun, Jisu , Hong, Ki Bum , Lee, Changwook , Lee, Ji Hoon , Kang, Byoung Heon , Kang, Soosung

Article Issue Date2020-08 View25

Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1 File

Jung, Sejin , Yoon, Nam Gu , Yang, Sujae , Kim, Darong , Lee, Won Seok , Hong, Ki Bum , Lee, Changwook , Kang, Byoung Heon , Lee, Ji Hoon , Kang, Soosung

Article Issue Date2020-01 View13

Ergosterol interacts with Sey1p to promote atlastin-mediated endoplasmic reticulum membrane fusion in Saccharomyces cerevisiae File

Lee, Miriam , Moon, Yeojin , Lee, Sanghwa , Lee, Changwook , Jun, Youngsoo

Article Issue Date2019-03 View12

GEN-Click: Genetically Encodable Click Reactions for Spatially Restricted Metabolite Labeling File

Mishra, Pratyush Kumar , Sharma, Nirmali , Kim, Hyunwoo , Lee, Changwook , Rhee, Hyun-Woo

Article Issue Date2023-08 View27

Genetically Encodable Bacterial Flavin Transferase for Fluorogenic Protein Modification in Mammalian Cells File

Kang, Myeong-Gyun , Park, Jumi , Balboni, Gianfranco , Lim, Mi Hee , Lee, Changwook , Rhee, Hyun-Woo

Article Issue Date2017-04 View14

Genotype and Phenotype Spectrum of FRMD7-Associated Infantile Nystagmus Syndrome File File

Choi, Jae-Hwan , Jung, Jae-Ho , Oh, Eun Hye , Shin, Jin-Hong , Kim, Hyang-Sook , Seo, Je Hyun , Choi, Seo Young , Kim, Min-Ji , Choi, Hee Young , Lee, Changwook , et al

Article Issue Date2018-06 View7

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) File

Klionsky, Daniel J. , Lee, Changwook

Article Issue Date2021-02 View13

Human atlastins are sufficient to drive the fusion of liposomes with a physiological lipid composition File

Jang, Eunhong , Moon, Yeojin , Yoon, So Young , Diaz, Joyce Anne R. , Lee, Miriam , Ko, Naho , Park, Jongseo , Eom, Soo Hyun , Lee, Changwook , Jun, Youngsoo

Article Issue Date2023-02 View20

Identification of a novel GPR143 mutation in X-linked ocular albinism with marked intrafamilial phenotypic variability File

Jung, Jae-Ho , Oh, Eun Hye , Shin, Jin-Hong , Kim, Hyang-Sook , Choi, Seo Young , Choi, Kwang-Dong , Lee, Changwook , Choi, Jae-Hwan

Article Issue Date2018-12 View11

Impaired DNA-binding affinity of novel PAX6 mutations File File

Lee, Seowhang , Lee, Seung-Han , Heo, Hwan , Oh, Eun Hye , Shin, Jin-Hong , Kim, Hyang-Sook , Jung, Jae-Ho , Choi, Seo Young , Choi, Kwang-Dong , Lee, Hakbong , et al

Article Issue Date2020-02 View20

Interactions of SV40 large T antigen and other viral proteins with retinoblastoma tumour suppressor File

Lee, Changwook , Cho, Y

Article Issue Date2002-03 View7

LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding File File

Lee, Hwan Hee , Sanada, Satoru , An, Seung Min , Ye, Byeong Jin , Lee, Jun Ho , Seo, Young Kyo , Lee, Changwook , Lee-Kwon, Whaseon , Kuper, Christoph , Neuhofer, Wolfgang , et al

Article Issue Date2016-04 View11

Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet File

Kwon, Taewoo , Chang, Jeong Ho , Kwak, Eunyee , Lee, Changwook , Joachimiak, Andrzej , Kim, Young Chang , Lee, Jae Woon , Cho, Yunje

Article Issue Date2003-01 View11

Mechanistic insight into phospholipid trafficking at ER-mitochondria Membrane contact sites.

Jeong, Hanbin , Park, Jumi , Jun, Youngsoo , Lee, Changwook

Conference Paper Issue Date2017-11-09 View8

Mechanistic Insight into the Nucleus-Vacuole Junction Based on the Vac8p-Nvj1p Crystal Structure

Jeong, Hanbin , Park, Jumi , Kim, Hye-In , Lee, Miriam , Ko, Young-Joon , Lee, Sanghwa , Jun, Youngsoo , Lee, Changwook

Conference Paper Issue Date2017-09-12 View10

Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure File

Jeong, Hanbin , Park, Jumi , Kim, Hye-In , Lee, Miriam , Ko, Young-Joon , Lee, Sanghwa , Jun, Youngsoo , Lee, Changwook

Article Issue Date2017-06 View10

Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site File

Yoon, Nam Gu , Lee, Hakbong , Kim, So-Yeon , Hu, Sung , Kim, Darong , Yang, Sujae , Hong, Ki Bum , Lee, Ji Hoon , Kang, Soosung , Kim, Byung-Gyu , et al

Article Issue Date2021-12 View32

Molecular mechanisms of atlastin-mediated ER membrane fusion revealed by a FRET-based single-vesicle fusion assay File File

Kim, Kyung Tae , Moon, Yeojin , Jang, Yunsu , Lee, Kang Taek , Lee, Changwook , Jun, Youngsoo , Lee, Sanghwa

Article Issue Date2017-08 View6

MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1 File

Oh, Jung-Min , Kang, Yujin , Park, Jumi , Sung, Yubin , Kim, Dayoung , Seo, Yuri , Lee, EunA , Ra, JaeSun , Amarsanaa, Enkhzul , Park, Young-Un , et al

Article Issue Date2023-06 View24

Novel Strategy To Inhibit Transthyretin Amyloidosis via the Synergetic Effect of Chemoselective Acylation and Noncovalent Inhibitor Release File

Lee, Seok Beom , Yu, Jaeni , Kim, Hyunwoo , Kim, Kun Woo , Jeong, Jong Woo , Kim, Yun Lan , Park, Sung Jean , Koo, Tae-Sung , Lee, Changwook , Hong, Ki Bum , et al

Article Issue Date2023-02 View17

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors File

Park, Hye-Kyung , Jeong, Hanbin , Ko, Eunhwa , Lee, Geumwoo , Lee, Ji-Eun , Lee, Sang Kwang , Lee, An-Jung , Im, Jin Young , Hu, Sung , Kim, Seong Heon , et al

Article Issue Date2017-09 View17

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors

Park, Hye-Kyung , Jeong, Hanbin , Ko, Eunhwa , Lee, Geunwoo , Lee, Ji-Eun , Lee, Sang Kwang , Lee, An-Jung , Lee, Jin Young , Hu, Sung , Kin, Seong Heon , et al

Conference Paper Issue Date2018-06-28 View10

Proximity-Directed Labeling Reveals a New Rapamycin-Induced Heterodimer of FKBP25 and FRB in Live Cells File File

Lee, Song-Yi , Lee, Hakbong , Lee, Hye-Kyeong , Lee, Seung-Won , Ha, Sung Chul , Kwon, Taejoon , Seo, Jeong Kon , Lee, Changwook , Rhee, Hyun-Woo

Article Issue Date2016-08 View15

Purification, crystallization, and X-ray crystallographic analysis of Vac8p complexed with Atg13p from Saccharomyces cerevisiae

Park, Jumi , Song, Kyonghwa , Oh, Sohyeon , Son, Taewon , Lee, Jun , Park, Ayoung , Kim, Hyun Ji , Jun, Youngsoo , Lee, Changwook

Article Issue Date2017-09 View4

Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways. File File

Park, Jumi , Kim, Hye-In , Jeong, Hanbin , Lee, Miriam , Jang, Se Hwan , Yoon, So Young , Kim, Hyejin , Park, Zee-Yong , Jun, Youngsoo , Lee, Changwook

Article Issue Date2020-06 View17

Rare Variants of Putative Candidate Genes Associated With Sporadic Meniere's Disease in East Asian Population File File

Oh, Eun Hye , Shin, Jin-Hong , Kim, Hyang-Sook , Cho, Jae Wook , Choi, Seo Young , Choi, Kwang-Dong , Rhee, Je-Keun , Lee, Seowhang , Lee, Changwook , Choi, Jae-Hwan

Article Issue Date2020-01 View21

ROGDI Defines a GABAergic Input to a Dopaminergic Neural Circuit to Promote Sleep in Drosophila

Kim, Minjong , Jang, Donghoon , Lee, Hakbong , Yoo, Eunseok , Oh, Yangkyun , Sonn, Jun Young , Lee, Jongbin , Son, Hyo Jin , Hwang, Onyou , Lee, Changwook , et al

Conference Paper Issue Date2016-10-12 View3

ROGDI defines a GABAergic input to a dopaminergic neural circuit to promote sleep in Drosophila

Kim, Minjong , Jang, Donghoon , Lee, Hakbong , Yoo, Eunseok , Oh, Yangkyun , Sonn, Jun Young , Lee, Jongbin , Son, Hyo Jin , Hwang, Onyou , Lee, Changwook , et al

Conference Paper Issue Date2016-09-28 View5

Rogdi Defines GABAergic Control of a Wake-promoting Dopaminergic Pathway to Sustain Sleep in Drosophila File File

Kim, Minjong , Jang, Donghoon , Yoo, Eunseok , Oh, Yangkyun , Sonn, Jun Young , Lee, Jongbin , Ki, Yoonhee , Son, Hyo Jin , Hwang, Onyou , Lee, Changwook , et al

Article Issue Date2017-09 View10

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin File

Lee, Changwook , Hong, BumSoo , Choi, Jung Min , Kim, Yugene , Watanabe, Saori , Ishimi, Yukio , Enomoto, Takemi , Tada, Shusuke , Kim, Youngchang , Cho, Yunje

Article Issue Date2004-08 View5

Structural Basis for Lipid Transport at ER-Mitochondrial Membrane Contact Sites

Lee, Changwook

Conference Paper Issue Date2022-11-03 View6

Structural basis for mitoguardin 2 mediated lipid transport at ER-mitochondrial membrane contact sites

Kim, Hyunwoo , Lee, Seowhang , Jun, Youngsoo , Lee, Changwook

Conference Paper Issue Date2022-09-28 View7

Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites File

Kim, Hyunwoo , Lee, Seowhang , Jun, Youngsoo , Lee, Changwook

Article Issue Date2022-06 View10

Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites

Kim, Hyunwoo , Lee, Seowhang , Jun, Youngsoo , Lee, Changwook

Conference Paper Issue Date2022-11-17 View8

Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor File

Lee, Changwook , Chang, Jeong Ho , Lee, Hyun Sook , Cho, Yunje

Article Issue Date2002-12 View8

Structural studies for the nucleus-vacuole junction (NVJ)

Lee, Changwook

Conference Paper Issue Date2017-10-24 View2

Structure and function of human Exonuclease 3'-5' domain-containing protein 2

Lee, Changwook

Conference Paper Issue Date2019-06-19 View6

Structure and function of Organelle Contact Sites

Jeong, Hanbin , Park, Jumi , Kim, Hey-In , Jun, Youngsoo , Lee, Changwook

Conference Paper Issue Date2018-01-18 View9

Structure of a peptide : N-glycanase-Rad23 complex: Insight into the deglycosylation for denatured glycoproteins File

Lee, Jung-Hoon , Choi, Jung Min , Lee, Changwook , Yi, Ki Joung , Cho, Yunje

Article Issue Date2005-06 View10

Structure of Coatomer Cage Proteins and the Relationship among COPI, COPII, and Clathrin Vesicle Coats File

Lee, Changwook , Goldberg, Jonathan

Article Issue Date2010-07 View5

Structure of mitochondrial CLPB reveals a mechanism for stand-alone disaggregase activity

Lee, Changwook

Conference Paper Issue Date2024-02-22 View24

Structure of SEL1L , a component of Endoplasmic Reticulum Associated Degradation

Jeong, Hanbin , Lee, Changwook

Conference Paper Issue Date2014-10-28 View9

Structure-guided synthesis of a protein-based fluorescent sensor for alkyl halides File

Kang, Myeong-Gyun , Lee, Hakbong , Kim, Beom Ho , Dunbayev, Yerkin , Seo, Jeong Kon , Lee, Changwook , Rhee, Hyun-Woo

Article Issue Date2017-08 View14

Structures of Vac8-containing protein complexes reveal the underlying mechanism by which Vac8 regulates multiple cellular processes File

Kim, Hyejin , Park, Jihyeon , Kim, Hyunwoo , Ko, Naho , Park, Jumi , Jang, Eunhong , Yoon, So Young , Diaz, Joyce Anne R , Lee, Changwook , Jun, Youngsoo

Article Issue Date2023-04 View21

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