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A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity File

Choi, Sun-Sil , Kim, Eun Sun , Koh, Minseob , Lee, Soo-Jin , Lim, Donghyun , Yang, Yong Ryoul , Jang, Hyun-Jun , Seo, Kyung-ah , Min, Sang-Hyun , Lee, In Hee , et al

Article Issue Date2014-09 View82

Ablation of PLCγ1 induces the dysfunction of dopaminergic neurons

Kim, Hye Yun , Lee, Jieun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2021-05-21 View29

An activator of the cAMP/PKA/CREB pathway promotes osteogenesis from human mesenchymal stem cells File

Kim, Jung-Min , Choi, Jin Seok , Kim, Yun-Hee , Jin, Seong Hui , Lim, Seyoung , Jang, Hyun-Jun , Kim, Kyong-Tai , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2013-03 View41

Characterization of physiological roles of PLCβ isozymes in pancreatic β-cells in vitro and in vivo

Hwang, Hyeon-Jeong , Jang, Hyun-Jun , Suh, Pann-Ghill

Conference Paper Issue Date2015-07-04 View23

Deletion of PLCγ1 in GABAergic neurons increases seizure susceptibility in aged mice File File

Kim, Hye Yun , Yang, Yong Ryoul , Hwang, Hongik , Lee, Ha-Eun , Jang, Hyun-Jun , Kim, Jeongyeon , Yang, Esther , Kim, Hyun , Rhim, Hyewhon , Suh, Pann-Ghill , et al

Article Issue Date2019-11 View54

Deletion of PLCγ1 in GABAergic neurons leads to seizures in mice

Kim, Hye Yun , Yang, Yong Ryoul , Hwang, Hongik , Jang, Hyun-Jun , Kim, Jeongyeon , Yang, Esther , Kim, Hyun , Rhim, Hyewhon , Kim, Jae-Ick , Suh, Pann-Ghill

Conference Paper Issue Date2019-09-24 View22

Deletion of PLCγ1 in GABAergic Neurons Leads to Spontaneous Seizure in Mice

Kim, Hye Yun , Yang, Yong Ryoul , Hwang, Hongik , Jang, Hyun-Jun , Kim, Jeongyeon , Yang, Esther , Kim, Hyun , Rhim, Hyewhon , Kim, Jae-Ick , Suh, Pann-Ghill

Conference Paper Issue Date2019-10-01 View32

Discovering regulators of insulin secretion by luminescent high-throughput screening in pancreatic β-cell

Hwang , Hyeon-Jeong , Jang, Hyun-Jun , Suh, Pann-Ghill

Conference Paper Issue Date2016-11-17 View16

Diverse cellular and physiological roles of phospholipase C-γ1 File

Yang, Yong Ryoul , Choi, Jang Hyun , Chang, Jong-Soo , Kwon, H. Moo , Jang, Hyun-Jun , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2012-01 View65

DJ-1 contributes to adipogenesis and obesity-induced inflammation File File

Kim, Jung-Min , Jang, Hyun-Jun , Choi, Soo Youn , Park, Soo-Ah , Kim, Il Shin , Yang, Yong Ryoul , Lee, Yong Hwa , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2014-06 View60

DJ-1 promotes angiogenesis and osteogenesis by activating FGF receptor-1 signaling File

Kim, Jung-Min , Shin, Hong-In , Cha, Sun-Shin , Lee, Chang Sup , Hong, Bok Sil , Lim, Seyoung , Jang, Hyun-Jun , Kim, Jaeyoon , Yang, Yong Ryoul , Kim, Yun-Hee , et al

Article Issue Date2012-12 View58

Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling File

Yang, Yong Ryoul , Kim, Dae Hyun , Seo, Young-Kyo , Park, Dohyun , Jang, Hyun-Jun , Choi, Soo Youn , Lee, Yong Hwa , Lee, Gyun Hui , Nakajima, Kazuki , Taniguchi, Naoyuki , et al

Article Issue Date2015-05 View59

Genetic deletion of PLCγ1 leads to the dysfunction of dopamine neurons

Kim, Hye Yun , Lee, Jieun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2021-05-26 View29

Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCer File

Jang, Hyun-Jun , Lim, Seyoung , Kim, Jung-Min , Yoon, Sora , Lee, Chae Young , Hwang, Hyeon-Jeong , Shim, Jeong Woo , Shin, Kyeong Jin , Kim, Hye Yun , Park, Kwang Il , et al

Article Issue Date2020-01 View87

GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis File

Lee, Yu Jin , Shin, Kyeong Jin , Jang, Hyun-Jun , Ryu, Jin-Sun , Lee, Chae Young , Yoon, Jong Hyuk , Seo, Jeong Kon , Park, Sabin , Lee, Semin , Je, A Reum , et al

Article Issue Date2023-02 View60

Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA File

Lee, Yo Han , Jang, Hyun-Jun , Kim, Sounkou , Choi, Sun Sil , Khim, Keon Woo , Eom, Hye-Jin , Hyun, Jimin , Shin, Kyeong Jin , Chae, Young Chan , Kim, Hongtae , et al

Article Issue Date2021-12 View68

Hypothalamic GABRA5-positive neurons control obesity via astrocytic GABA File

Sa, Moonsun , Yoo, Eun-Seon , Koh, Wuhyun , Park, Mingu Gordon , Jang, Hyun-Jun , Yang, Yong Ryoul , Bhalla, Mridula , Lee, Jae-Hun , Lim, Jiwoon , Won, Woojin , et al

Article Issue Date2023-09 View46

Itgbl1 modulate integrin activity to promote cartilage formation and protect against arthritis

Song, Eun Kyung , Jeon, Jimin , Jang, Dong Gil , Kim, Ha Eun , Sim, Hyo Jung , Kwon, Keun Yeong , Medina-ruiz, Sofia , Jang, Hyun-Jun , Lee, Ah Reum , Rho, Jun Gi , et al

Conference Paper Issue Date2019-10-01 View30

ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis. File

Song, Eun Kyung , Jeon, Jimin , Jang, Dong Gil , Kim, Ha Eun , Sim, Hyo Jung , Kwon, Keun Yeong , Medina-Ruiz, Sofia , Jang, Hyun-Jun , Lee, Ah Reum , Rho, Jun Gi , et al

Article Issue Date2018-10 View76

Loss of DJ-1 promotes browning of white adipose tissue in diet-induced obese mice File

Silvester, Allwin Jennifa , Aseer, Kanikkai Raja , Jang, Hyun-Jun , Ryu, Ri , Kwon, Eun-Young , Park, Jae Gyu , Cho, Kiu-Hyung , Chaudhari, Harmesh N. , Choi, Myung-Sook , Suh, Pann-Ghill , et al

Article Issue Date2018-11 View35

Loss of phospholipase C gamma 1 suppresses hepatocellular carcinogenesis through blockade of STAT3-mediated cancer development File

Seo, Eun-Bi , Jang, Hyun-Jun , Kwon, Sun-Ho , Kwon, Yong-Jin , Kim, Seul-Ki , Lee, Song-Hee , Jeong, Ae Jin , Shin, Hyun Mu , Kim, Yong-Nyun , Ma, Stephanie , et al

Article Issue Date2022-11 View71

Metabolic Regulation by Phospholipase C gammal

Jang, Hyun-Jun , Suh, Pann-Ghill

Conference Paper Issue Date2016-07-21 View52

Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivity File

Choi, Sunsil , Jung, Ji-Eun , Yang, Yong Ryoul , Kim, Eun-Sun , Jang, Hyun-Jun , Kim, Eung-Kyun , Kim, Il Shin , Lee, Joo-Young , Kim, Joong Kwan , Seo, Jeong Kon , et al

Article Issue Date2015-12 View30

O-GlcNAc cycling enzymes control vascular development of the placenta by modulating the levels of HIF-1α File

Yang, Yong Ryoul , Jang, Hyun-Jun , Lee, Yong Hwa , Kim, Il Shin , Lee, Ho , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2015-10 View65

O-GlcNAcase is essential for embryonic development and maintenance of genomic stability File File

Yang, Yong Ryoul , Song, Minseok , Lee, Ho , Jeon, Yoon , Choi, Eun-Jeong , Jang, Hyun-Jun , Moon, Hyo Youl , Byun, Ha-Young , Kim, Eung-Kyun , Kim, Dae Hyun , et al

Article Issue Date2012-06 View86

Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice. File

Yang, Yong Ryoul , Jang, Hyun-Jun , Choi, Sun-Sil , Lee, Yong Hwa , Lee, Gyun Hul , Seo, Young-Kyo , Choi, Jang Hyun , Park, Dohyun , Koh, Ara , Kim, Il Shin , et al

Article Issue Date2015-12 View57

Ochratoxin A Inhibits Adipogenesis Through the Extracellular Signal-Related Kinases-Peroxisome Proliferator-Activated Receptor-g Pathway in Human Adipose Tissue-Derived Mesenchymal Stem Cells File

Lim, Seyoung , Jang, Hyun-Jun , Kim, Jung Kuk , Kim, Jung-Min , Park, Eun Hee , Yang, Jun Hyuk , Kim, Yun-Hee , Yea, Kyungmoo , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2011-03 View55

Phospholipase C gamma 1 is required for normal irritant contact dermatitis responses and sebaceous gland homeostasis File

Fukuyama, Takatsugu , Nakamura, Yoshikazu , Kanemaru, Kaori , Toyoda, Chiho , Jang, Hyun-Jun , Suh, Pann-Ghill , Fukami, Kiyoko

Article Issue Date2019-09 View45

Phospholipase C gamma 1 represses colorectal cancer growth by inhibiting the Wnt/beta-catenin signaling axis File

Shin, Kyeong Jin , Jang, Hyun-Jun , Lee, Yu Jin , Lee, Yu Geon , Suh, Pann-Ghill , Yang, Yong Ryoul , Chae, Young Chan

Article Issue Date2021-09 View59

Phospholipase C-gamma 1 involved in brain disorders File

Jang, Hyun-Jun , Yang, Yong Ryoul , Kim, Jung Kuk , Choi, Jang Hyun , Seo, Young-Kyo , Lee, Yong Hwa , Lee, Jeung Eun , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2013-01 View53

Phospholipase C-β1 potentiates glucose-stimulated insulin secretion File

Hwang, Hyeon-Jeong , Yang, Yong Ryoul , Kim, Hye Yun , Choi, Yoonji , Park, Kyoung-Su , Lee, Ho , Ma, Ji Su , Yamamoto, Masahiro , Kim, Jaeyoon , Chae, Young Chan , et al

Article Issue Date2019-10 View50

Phospholipase Signaling in Breast Cancer File

Lee, Yu Jin , Shin, Kyeong Jin , Jang, Hyun-Jun , Noh, Dong-Young , Ryu, Sung Ho , Suh, Pann-Ghill

Article Issue Date2021-05 View46

PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2

Kim, Hye Yun , Lee, Jieun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2022-05-25 View32

PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III

Kim, Hye Yun , Lee, Jieun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2022-05-20 View27

PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III

Lee, Jieun , Kim, Hye Yun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2023-11-07 View81

PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III

Kim, Hye Yun , Lee, Jieun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2023-05-12 View31

PLCγ1: Potential arbitrator of cancer progression File

Jang, Hyun-Jun , Suh, Pann-Ghill , Lee, Yu Jin , Shin, Kyeong Jin , Cocco, Lucio , Chae, Young Chan

Article Issue Date2018-01 View141

PPAR gamma Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose Tissue File

Choi, Sun-sil , Kim, Eun-Sun , Jung, Ji-Eun , Marciano, David P. , Jo, Ala , Koo, Ja Young , Choi, Soo Youn , Yang, Yong Ryoul , Jang, Hyun-Jun , Kim, Eung-Kyun , et al

Article Issue Date2016-04 View78

PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273 File File

Khim, Keon Woo , Choi, Sun Sil , Jang, Hyun-Jun , Lee, Yo Han , Lee, Eujin , Hyun, Ji-Min , Eom, Hye-Jin , Yoon, Sora , Choi, Jeong-Won , Park, Tae-Eun , et al

Article Issue Date2020-02 View81

Prediction of Alzheimer's disease-specific phospholipase c gamma-1 SNV by deep learning-based approach for high-throughput screening File

Kim, Sung-Hyun , Yang, Sumin , Lim, Key-Hwan , Ko, Euiseng , Jang, Hyun-Jun , Kang, Mingon , Suh, Pann-Ghill , Joo, Jae-Yeol

Article Issue Date2021-01 View38

Propyl Gallate Inhibits Adipogenesis by Stimulating Extracellular Signal-Related Kinases in Human Adipose Tissue-Derived Mesenchymal Stem Cells File File

Lee, Jeung-Eun , Kim, Jung-Min , Jang, Hyun-Jun , Lim, Se-young , Choi, Seon-Jeong , Lee, Nan-Hee , Suh, Pann-Ghill , Choi, Ung-Kyu

Article Issue Date2015-04 View70

Regulation of striatal dopamine release by PLCg1 in dopamine neurons: Involvement of VMAT2 and Synapsin Ill

Kim, Hye Yun , Lee, Jieun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2024-05-30 View16

Regulation of striatal dopamine release by PLCγ1 in dopamine neurons: Involvement of VMAT2 and Synapsin III

Kim, Hye Yun , Lee, Jieun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2023-09-06 View29

SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy File File

Kim, Kwang-Youn Kim , Jang, Hyun-Jun , Yang, Yong Ryul , Park, Kwang-Il , Seo, Jeong Kon , Shin, Il-Woo , Jeon, Tae-Il , Ahn, Soon-cheol , Suh, Pann-Ghill , Osborne, Timothy F. , et al

Article Issue Date2016-10 View73

The Deletion of PLCγ1 Alters Physiological Features of Dopaminergic Neuron

Kim, Hye Yun , Lee, Jieun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2021-11-05 View32

The deletion of PLCγ1 leads to the dysfunction of dopaminergic neuron

Kim, Hye Yun , Lee, Jieun , Kim, Hyun-Jin , Jang, Hyun-Jun , Suh, Pann-Ghill , Kim, Jae-Ick

Conference Paper Issue Date2020-11-17 View29

The regulation of insulin secretion via phosphoinositide-specific phospholipase Cβ signaling File

Hwang, Hyeon-Jeong , Jang, Hyun-Jun , Cocco, Lucio , Suh, Pann-Ghill

Article Issue Date2019-01 View48

Thrap3 docks on phosphoserine 273 of PPAR gamma and controls diabetic gene programming File

Choi, Jang Hyun , Choi, Sun-Sil , Kim, Eun Sun , Jedrychowski, Mark P. , Yang, Yong Ryoul , Jang, Hyun-Jun , Suh, Pann-Ghill , Banks, Alexander S. , Gygi, Steven P. , Spiegelman, Bruce M.

Article Issue Date2014-11 View69

Vernicia fordii (Hemsl.) Airy Shaw extract stimulates insulin secretion in pancreatic beta-cells and improves insulin sensitivity in diabetic mice File

Hyun, Jimin , Park, Mi Hyeon , Lee, Yo Han , Lee, Youngeun , Jeong, Su Ji , Choi, Sun Sil , Khim, Keon Woo , Eom, Hye Jin , Hur, Jin-Hoe , Park, Chan Young , et al

Article Issue Date2021-10 View98

Wedelolactone inhibits adipogenesis through the ERK pathway in human adipose tissue-derived mesenchymal stem cells File

Lim, Seyoung , Jang, Hyun-Jun , Park, Eun Hee , Kim, Jung Kuk , Kim, Jung-Min , Kim, Eung-Kyun , Yea, Kyungmoo , Kim, Yun-Hee , Lee-Kwon, Whaseon , Ryu, Sung Ho , et al

Article Issue Date2012-11 View79

Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channels File

Hwang, Hyeon-Jeong , Park, Kyoung-Su , Choi, Jang Hyun , Cocco, Lucio , Jang, Hyun-Jun , Suh, Pann-Ghill

Article Issue Date2018-05 View57

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