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김철민
Ghim, Cheol-Min

김철민

Department of Physics(물리학과)

  • Physical Biology Biological Physics Lab.
  • Website
Research Interests
Control of complex networks;Nonequilibrium statistical physics;Stochastic cell biology;Biochemical information processing;Human microbiome;Ecological inference;Reinforcement learning;Network biology
Lab Description
The Ghim Lab seeks to find the “design” principles behind the networks of biological information processing. The networks encompass cellular metabolism, regulation of gene expression, cell-to-cell communication, and up to social and ecological interactions among individuals. The current focus of research is on:
• Control and exploitation of noise in gene expression• Resource allocation for coordinated metabolism• Causal inference in epidemic dynamics and ecological systems• Game theory in structured populations and reinforcement learning
The aim from biology side is to rationalize the efficiency and robustness of biological networks in the light of form-function duality. The other side of the coin is an effort to restore the precision and accuracy of biochemical information processing in e.g. synthetic biology or metabolic engineering up to its silicon-based counterpart. Both of these objectives are closely linked to the fundamental problems of equilibrium and nonequilibrium statistical mechanics on complex networks. Information theory and statistical physics are a major tool toward this end but the crux is still the rigorous biological realism.
Researcher ID Research Gate ORCiD Scopus Google Scholar
Previous
Intelligent Soft Matter: Towards Embodied Intelligence File

Baulin, Vladimir A. , Ghim, Cheol-Min , Hanczyc, Martin M.

Article Issue Date2025-05 View0
Enlightening the blind spot of the Michaelis-Menten rate law: The role of relaxation dynamics in molecular complex formation File

Chae, Junghun , Lim, Roktaek , Martin, Thomas L. P. , Ghim, Cheol-Min , Kim, Pan-Jun

Article Issue Date2025-01 View3
Generalized Michaelis-Menten rate law with time-varying molecular concentrations File File

Lim, Roktaek , Martin, Thomas L. P. , Chae, Junghun , Kim, WooJoong , Ghim, Cheol-Min , Kim, Pan-Jun

Article Issue Date2023-12 View60
The Boltzmann fair division for distributive justice File File

Park Ji-Won , Kim, Jaeup U. , Ghim, Cheol-Min , Kim, Chae Un

Article Issue Date2022-09 View107
Propagation of stochastic fluctuations in RNA polymerase abundance in constitutive gene expression File

Jang, Juneil , Ghim, Cheol-Min

Article Issue Date2022-01 View58
Backward simulation for inferring hidden biomolecular kinetic profiles File File

Chae, Junghun , Lim, Roktaek , Ghim, Cheol-Min , Kim, Pan-Jun

Article Issue Date2021-12 View56
Heterogeneity is not always a source of noise: Stochastic gene expression in regulatory heterozygote File

Jang, Juneil , Amblard, Francois , Ghim, Cheol-Min

Article Issue Date2021-10 View86
Cost-effective circadian mechanism: rhythmic degradation of circadian proteins spontaneously emerges without rhythmic post-translational regulation File File

Lim, Roktaek , Chae, Junghun , Somers, David E. , Kim, Pan-Jun , Ghim, Cheol-Min

Article Issue Date2021-07 View74
Photoacoustic Tomography Opening New Paradigms in Biomedical Imaging File

Yang, Joon Mo , Ghim, Cheol-Min

Article Issue Date2021-04 View67
Elucidating the role of metal ions in carbonic anhydrase catalysis File File

Kim, Jin Kyun , Lee, Cheol , Lim, Seon Woo , Andring, Jacob T. , Adhikari, Aniruddha , McKenna, Robert , Ghim, Cheol-Min , Kim, Chae Un

Article Issue Date2020-09 View82
Large-scale metabolic interaction network of the mouse and human gut microbiota File File

Lim, Roktaek , Cabatbat, Josephine Jill T. , Martin, Thomas L. P. , Kim, Haneul , Kim, Seunghyeon , Sung, Jaeyun , Ghim, Cheol-Min , Kim, Pan-Jun

Article Issue Date2020-06 View90
The KIAS-APCTP Winter School on Statistical Physics: 16 Years of Education

Ghim, Cheol-Min

Article Issue Date2019-04 View65
Effects of Zygosity on Stochastic Gene Expression of Diploid Cells File

Yang, Hyunmo , Jang, Juneil , Ghim, Cheol-Min

Article Issue Date2019-02 View58
Serum albumin and osmolality inhibit Bdellovibrio bacteriovorus predation in human serum File File

Im, Hansol , Son, Sangmo , Mitchell, Robert J. , Ghim, Cheol-Min

Article Issue Date2017-07 View81
세포 내 생체회로의 “설계” 원리 File

조정효 , 김철민

Article Issue Date2016-10 View51
Selected heterozygosity at cis-regulatory sequences increases the expression homogeneity of a cell population in humans File File

Sung, Min Kyung , Jang, Juneil , Lee, Kang Seon , Ghim, Cheol-Min , Choi, Jung Kyoon

Article Issue Date2016-07 View50
Hypothetical biomolecular probe based on a genetic switch with tunable symmetry and stability File File

Martyushenko, Nikolay , Johansen, Sigurd Haegen , Ghim, Cheol-Min , Almaas, Eivind

Article Issue Date2016-06 View52
Shedding Light on Microbial Predator-Prey Population Dynamics Using a Quantitative Bioluminescence Assay File

Im, Hansol , Kim, Dasol , Ghim, Cheol-Min , Mitchell, Robert J.

Article Issue Date2014-01 View77
Rewiring carbon catabolite repression for microbial cell factory File File

Vinuselvi, Parisutham , Kim, Min Kyung , Lee, Sung Kuk , Ghim, Cheol-Min

Article Issue Date2012-02 View166
부품소재은행

이재명 , 김태성 , 김철민 , 이성국

Article Issue Date2011-03 View39
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