Kim, Chae Un (김채운)

Department

Department of Physics(물리학과)

Website

http://hiprex.unist.ac.kr

Lab

High Pressure X-ray Science Lab. (고압력 X-선 생물물리 연구실)

Research Keywords

엑스레이, 엑스선, 생물물리학, 의생명과학, 바이오메디컬, X-ray Science, Biophysical Science, Biomedical Science

Research Interests

Our lab studies biological and soft matter systems using high pressure and X-ray techniques. A high-pressure cryocooling method was developed for crystal cryoprotection in macromolecular crystallography. In addition, the method was successfully applied to stabilize ligand-protein interactions, to study the pressure effect on the structure, and to entrap an intermediate enzymatic state. Using the high-pressure method, we will study the phase behaviors of glassy water, water-protein interactions, and protein functions and dynamics at cryogenic temperatures.