사진

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Ghim, Cheol-Min (김철민)

Department
Department of Physics(물리학과)
Website
http://pbbp.unist.ac.kr/
Lab
Physical Biology Biological Physics Lab. (이론생물물리 연구실)
Research Keywords
Control of complex networks, Nonequilibrium statistical physics, Stochastic cell biology, Biochemical information processing, Human microbiome, Ecological inference, Reinforcement learning, Network biology
Research Interests
The Ghim Lab seeks to find the “design” principles behind the networks of biological information processing. The networks encompass cellular metabolism, regulation of gene expression, cell-to-cell communication, and up to social and ecological interactions among individuals. The current focus of research is on:
• Control and exploitation of noise in gene expression• Resource allocation for coordinated metabolism• Causal inference in epidemic dynamics and ecological systems• Game theory in structured populations and reinforcement learning
The aim from biology side is to rationalize the efficiency and robustness of biological networks in the light of form-function duality. The other side of the coin is an effort to restore the precision and accuracy of biochemical information processing in e.g. synthetic biology or metabolic engineering up to its silicon-based counterpart. Both of these objectives are closely linked to the fundamental problems of equilibrium and nonequilibrium statistical mechanics on complex networks. Information theory and statistical physics are a major tool toward this end but the crux is still the rigorous biological realism.
This table browses all dspace content
Issue DateTitleAuthor(s)TypeViewAltmetrics
2020-09Elucidating the role of metal ions in carbonic anhydrase catalysisKim, Jin Kyun; Lee, Cheol; Lim, Seon Woo, et alARTICLE105 Elucidating the role of metal ions in carbonic anhydrase catalysis
2020-06Large-scale metabolic interaction network of the mouse and human gut microbiotaLim, Roktaek; Cabatbat, Josephine Jill T.; Martin, Thomas L. P., et alARTICLE167 Large-scale metabolic interaction network of the mouse and human gut microbiota
2019-04The KIAS-APCTP Winter School on Statistical Physics: 16 Years of EducationGhim, Cheol-MinARTICLE88
2019-02Effects of Zygosity on Stochastic Gene Expression of Diploid CellsYang, Hyunmo; Jang, Juneil; Ghim, Cheol-MinARTICLE367 Effects of Zygosity on Stochastic Gene Expression of Diploid Cells
2017-07Serum albumin and osmolality inhibit Bdellovibrio bacteriovorus predation in human serumIm, Hansol; Son, Sangmo; Mitchell, Robert J., et alARTICLE896 Serum albumin and osmolality inhibit Bdellovibrio bacteriovorus predation in human serum
2016-10세포 내 생체회로의 “설계” 원리조정효; 김철민ARTICLE581 세포 내 생체회로의 “설계” 원리
2016-07Selected heterozygosity at cis-regulatory sequences increases the expression homogeneity of a cell population in humansSung, Min Kyung; Jang, Juneil; Lee, Kang Seon, et alARTICLE740 Selected heterozygosity at cis-regulatory sequences increases the expression homogeneity of a cell population in humans
2016-06Hypothetical biomolecular probe based on a genetic switch with tunable symmetry and stabilityMartyushenko, Nikolay; Johansen, Sigurd Haegen; Ghim, Cheol-Min, et alARTICLE645 Hypothetical biomolecular probe based on a genetic switch with tunable symmetry and stability
2014-01Shedding Light on Microbial Predator-Prey Population Dynamics Using a Quantitative Bioluminescence AssayIm, Hansol; Kim, Dasol; Ghim, Cheol-Min, et alARTICLE1090 Shedding Light on Microbial Predator-Prey Population Dynamics Using a Quantitative Bioluminescence Assay
2012-02Rewiring carbon catabolite repression for microbial cell factoryVinuselvi, Parisutham; Kim, Min Kyung; Lee, Sung Kuk, et alARTICLE1037 Rewiring carbon catabolite repression for microbial cell factory
2011-03Engineering microorganisms for biofuel productionParisutham, Vinuselvi; Park, Jung Min; Lee, Jae Myung, et alARTICLE929 Engineering microorganisms for biofuel production
2011-03부품소재은행이재명; 김태성; 김철민, et alARTICLE476
2011-01Microbial linguistics: perspectives and applications of microbial cell-to-cell communicationMitchell, Robert J.; Lee, Sung Kuk; Kim, Taesung, et alARTICLE1137 Microbial linguistics: perspectives and applications of microbial cell-to-cell communication
2010-07The art of reporter proteins in science: past, present and future applicationsGhim, Cheol-Min; Lee, Sung Kuk; Takayama, Shuichi, et alARTICLE931 The art of reporter proteins in science: past, present and future applications
2010-01Synthetic Biology for Biofuels: Building Designer Microbes from the ScratchGhim, Cheol-Min; Kim, Taesung; Mitchell, Robert J., et alARTICLE1074 Synthetic Biology for Biofuels: Building Designer Microbes from the Scratch
2009-07Two-Component Genetic Switch as a Synthetic Module with Tunable StabilityGhim, Cheol-Min; Almaas, E.ARTICLE648 Two-Component Genetic Switch as a Synthetic Module with Tunable Stability
2009-04The Fixation Probability of Rare Mutators in Finite Asexual PopulationsWylie, C. Scott; Ghim, Cheol-Min; Kessler, David, et alARTICLE638 The Fixation Probability of Rare Mutators in Finite Asexual Populations
2009Systems biology of microbial communitiesNavid, A.; Ghim, Cheol-Min; Fenley, A.T., et alARTICLE780 Systems biology of microbial communities
2008-11Genetic noise control via protein oligomerizationGhim, Cheol-Min; Almaas, EivindARTICLE735 Genetic noise control via protein oligomerization
2007-10Scale-Free Networks in Contemporary BiologyGhim, Cheol-Min; Navid, Ali; Almaasm, EivindARTICLE618

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