Scholarworks@UNIST: Browsing Repository

Loops of HIF1a and Cyclophilin D promote cancer netastasis through long-term ROS signaling.

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2020-10-08 View7

Microenvironment-adapted mitochondria promote metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2023-05-08 View5

Mitochondria adapted to the microenvironment of primary tumors promote cancer metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2023-06-16 View4

Mitochondria target therapy through inhibition TRAP1-IDH2 to treat relapse/refractory acute myeloid leukemia

Sung Hu , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-02-16 View7

Mitochondria target therapy through inhibition TRAP1-IDH2 to treat relapse/refractory AML

Hu, Sung , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-08-26 View11

Mitochondria-ER crosstalk and combination cancer therapy

Kang, Byoung Heon

Conference Paper Issue Date2012 View1

Mitochondria-targeted Hsp90 inhibitors as novel anticancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2011 View1

Mitochondria-targeted Hsp90 inhibitors as novel anticancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2010 View2

Mitochondrial Chaperone Protein, TRAP1 Modulates Mitochondrial Integrity by Regulating SSBP1(Single- Strand DNA Binding Protein 1).

Lee, JH , Kim, SY , Kang, Byoung Heon

Conference Paper Issue Date2022-08-26 View5

Mitochondrial Chaperone Protein, TRAP1 Modulates Mitochondrial Integrity by Regulating SSBP1(Single- Strand DNA Binding Protein 1).

Lee, JH , Kim, SY , Kang, Byoung Heon

Conference Paper Issue Date2022-02-16 View8

Mitochondrial chaperone TRAP1 and mitochondria-targeted inhibitor development

Kang, Byoung Heon

Conference Paper Issue Date2015-09-18 View5

Mitochondrial chaperone TRAP1 in human disease progression

Kang, Byoung Heon

Conference Paper Issue Date2022-09-28 View6

Mitochondrial chaperone TRAP1 is essential for pathologic vascular changes in ischemic retinopathy

Kim, So-Yeon , Yoon, Nam Gu , Lee, Ji hye , Kim, Jaeho , Yeom, Sun A , Park, Dong Ho , Kang, Byoung Heon

Conference Paper Issue Date2023-09-21 View10

Mitochondrial chaperone TRAP1 maintains stemness properties of glioma stem cells

박혜경 , 강병헌

Conference Paper Issue Date2017-07-14 View3

Mitochondrial chaperone TRAP1 regulates ATPase inhibitory factor 1 (ATPIF1) in glioblastoma

Baek, Ji Hun , Kang, Byoung Heon

Conference Paper Issue Date2022-09-28 View6

Mitochondrial chaperone TRAP1: structure, function, and inhibitors

Kang, Byoung Heon

Conference Paper Issue Date2015-06-18 View1

Mitochondrial Chaperone, TRAP1 Regulates Anoikis Resistance and Promotes Metastatic Potential.

Sun A Yeom , Kang, Byoung Heon

Conference Paper Issue Date2023-02-22 View7

Mitochondrial Chaperone, TRAP1 Regulates GLS1 (Glutaminase 1) in Cancer Cells.

백지훈 , 염선아 , Kang, Byoung Heon

Conference Paper Issue Date2022-08-26 View3

Mitochondrial Chaperones and Cancer Drug Development

Kang, Byoung Heon

Conference Paper Issue Date2014-04-17 View3

Mitochondrial Heat Shock Protein-Guided Photodynamic Therapy File

Thomas, Ajesh P. , Lee, An-Jung , Palanikumar, L , Jana, Batakrishna , Kim, Kibeom , Kim, Sangpil , Ok, Haewon , Seol, Jihoon , Kim, Dongseok , Kang, Byoung Heon , et al

Article Issue Date2019-10 View23

Mitochondrial Hsp90s increase threshold of cell death through suppression of propagating calcium signal from mitochondria to ER

Kang, Byoung Heon , Park, Hye Kyung , Lee, Ji Eun

Conference Paper Issue Date2013 View6

Mitochondrial Hsp90s suppress calcium signals propagating from mitochondria to the ER

Kang, Byoung Heon , None

Conference Paper Issue Date2013-05-15 View4

Mitochondrial Hsp90s suppress calcium signals propagating from mitochondria to the ER

Kang, Byoung Heon

Conference Paper Issue Date2013-11-05 View3

Mitochondrial Hsp90s suppress calcium signals propagating from mitocondria to the ER

Kang, Byoung Heon , None

Conference Paper Issue Date2013 View2

Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells File File

Park, Hye-Kyung , Lee, Ji-Eun , Lim, Jaehwa , Kang, Byoung Heon

Article Issue Date2014-06 View9

Mitochondrial life or death decision in cancer cells

Kang, Byoung Heon

Conference Paper Issue Date2012 View1

Mitochondrial regulation accelerates cancer Metastasis.

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-09-29 View8

Mitochondrial Thermogenesis Can Trigger Heat Shock Response in the Nucleus File File

Kang, Myeong-Gyun , Kim, Hwa-Ryeon , Lee, Hee Yong , Kwak, Chulhwan , Koh, Hyewon , Kang, Byoung Heon , Roe, Jae-Seok , Rhee, Hyun-Woo

Article Issue Date2024-06 View26

MitoQ inactivates mitochondrial chaperone TRAP1 by interacting with the client binding site

Yoon, Nam Gu , Kang, Byoung Heon

Conference Paper Issue Date2021-12-10 View8

Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site File

Yoon, Nam Gu , Lee, Hakbong , Kim, So-Yeon , Hu, Sung , Kim, Darong , Yang, Sujae , Hong, Ki Bum , Lee, Ji Hoon , Kang, Soosung , Kim, Byung-Gyu , et al

Article Issue Date2021-12 View33

Molecular cloning, expression, and purification of nuclear inclusion A protease from tobacco vein mottling virus File

Hwang, DC , Kim, DH , Kang, Byoung Heon , Song, BD , Choi, KY

Article Issue Date2000-04 View9

Novel in vivo pan-Hsp90 family inhibitor, panvotinib-401, showed potent anticancer activities without HSF1 activation

Kang, Byoung Heon

Conference Paper Issue Date2016-04-22 View2

Novel in vivo pan-Hsp90 family protein inhibitor, Panvotinib-401, promote anticancer activities by suppressing HSF1 activity

Park, Hey-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2016-11-02 View3

Novel TRAP1 inhibitor targeting the allosteric drug binding site showed improved anti-cancer activity

Hu, Sung , Yoon, Namgu , Kang, Byoung Heon

Conference Paper Issue Date2019-06-19 View4

OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ mice File File

Yang, Yongryoul , Jang H.J. , Yoon, Sunyoung , Lee, Yonghwa , Nam, Dougu , Kim, I.S. , Lee, Heeseok , Kim, Hyun , Choi, Jang Hyun , Kang, Byoung Heon , et al

Article Issue Date2014-07 View18

Oncogenic isocitrate dehydrogenase 2 is powerfully targeted by inhibition of a mitochondrial chaperone

허성 , 강병헌

Conference Paper Issue Date2018-11-07 View7

Open and closed conformation TRAP1 crystal structures and development of a purine scaffold mitochondria-targeted Hsp90 inhibitor

Kang, Byoung Heon , None

Conference Paper Issue Date2014-10-16 View4

Overcoming Chemo-resistance through TRAP1 Inhibition Targeting High Mitochondrial Activity in Relapse/Refractory Acute Myeloid Leukemia

Hu, Sung , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-09-29 View7

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors File

Park, Hye-Kyung , Jeong, Hanbin , Ko, Eunhwa , Lee, Geumwoo , Lee, Ji-Eun , Lee, Sang Kwang , Lee, An-Jung , Im, Jin Young , Hu, Sung , Kim, Seong Heon , et al

Article Issue Date2017-09 View18

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors

Park, Hye-Kyung , Jeong, Hanbin , Ko, Eunhwa , Lee, Geunwoo , Lee, Ji-Eun , Lee, Sang Kwang , Lee, An-Jung , Lee, Jin Young , Hu, Sung , Kin, Seong Heon , et al

Conference Paper Issue Date2018-06-28 View10

PDZ Domain-containing 1 (PDZK1) Protein Regulates Phospholipase C-beta 3 (PLC-beta 3)-specific Activation of Somatostatin by Forming a Ternary Complex with PLC-beta 3 and Somatostatin Receptors File

Kim, Jung Kuk , Kwon, Ohman , Kim, Jinho , Kim, Eung-Kyun , Park, Hye Kyung , Lee, Ji Eun , Kim, Kyung Lock , Choi, Jung Woong , Lim, Seyoung , Seok, Heon , et al

Article Issue Date2012-06 View8

Possibility of metabolic control mechanism by Tumor necrosis factor receptor-associated protein 1 (TRAP1) regulating pyruvate dehydrogenase (PDH)

Lee, Anjung , Kang, Byoung Heon

Conference Paper Issue Date2017-05-18 View2

Preclinical Characterization of Mitochondria-Targeted Small Molecule Hsp90 Inhibitors, Gamitrinibs, in Advanced Prostate Cancer File

Kang, Byoung Heon , Siegelin, Markus D. , Plescia, Janet , Raskett, Christopher M. , Garlick, David S. , Dohi, Takehiko , Lian, Jane B. , Stein, Gary S. , Languino, Lucia R. , Altieri, Dario C.

Article Issue Date2010-10 View12

Pro-tumorigenic function of cancer-associated adipocytes depends on the mitochondrial chaperone, TRAP1

Yoon, Nam Gu , Kim, So-Yeon , Kong, Sun-Young , Kang, Byoung Heon

Conference Paper Issue Date2023-09-21 View6

Quaternary ammonium-based mitochondria targeting anticancer agents with high water solubility File

Kim, Sangpil , Yoon, Nam Gu , Jana, Batakrishna , Kang, Byoung Heon , Ryu, Ja-Hyoung

Article Issue Date2022-03 View20

Regulation of cell death by mitochondrial chaperone networks in cancer cells

Kang, Byoung Heon

Conference Paper Issue Date2011 View2

Regulation of cell death by mitochondrial Hsp90s

Kang, Byoung Heon

Conference Paper Issue Date2010 View2

Regulation of cellular metabolism by mitochondrial chaperone TRAP1: therapeutic opportunities

Kang, Byoung Heon

Conference Paper Issue Date2019-05-09 View9

Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein File

Kang, Byoung Heon , Altieri, Dario C.

Article Issue Date2006-08 View10

Regulation of TRAP1 and SIRT3 in glioma stem cells

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2019-06-19 View4

Regulation of tumor cell mitochondrial Homeostasis by an organelle-specific Hsp90 chaperone network File

Kang, Byoung Heon , Plescia, Janet , Dohi, Takehiko , Rosa, Jack , Doxsey, Stephen J. , Altieri, Dario C.

Article Issue Date2007-10 View6

ROS dependent HIF-1α and CypD negative feedback promotes hypoxia-induced cancer metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2021-12-10 View7

ROS dependent HIF-1α/CypD negative feedback promotes hypoxia-induced cancer metastasis.

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2021-08-25 View7

ROS regulation by Cyclophilin D contributes cancer metastasis via hypoxic signaling

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2020-10-05 View4

Simultaneous inhibition of Hsp90 family proteins promotes apoptotic cell death via calcineurin activity

Park, Hye-Kyung , Noh, Dong Yeon , Kang, Byoung Heon

Conference Paper Issue Date2017-05-18 View4

SMx inactivates mitochondrial chaperone TRAP1 by interacting with the client binding site

Yoon, Nam Gu , Kang, Byoung Heon

Conference Paper Issue Date2021-08-25 View8

SSBP1 (Single Strand DNA Binding Protein), Binds To TRAP1, A Chaperone Protein In The Mitochondria, To Maintain Mitochondrial Integrity

Lee, Ji Hye , Kang, Byoung Heon

Conference Paper Issue Date2023-11-06 View6

SSBP1, a single-strand DNA binding protein 1, maintains mitochondrial integrity by modulating the mitochondrial chaperone protein TRAP1.

Lee, Ji Hye , Kang, Byoung Heon

Conference Paper Issue Date2023-02-22 View9

Stress signal propagation from mitochondria to ER and development of combination cancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2012 View2

Structure, Function, and Inhibitors of the Mitochondrial Chaperone TRAP1 File

Kang, Soo Sung , Kang, Byoung Heon

Article Issue Date2022-12 View18

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