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Mitochondrial chaperone TRAP1 in human disease progression

Kang, Byoung Heon

Conference Paper Issue Date2022-09-28 View6

Mitochondrial chaperone TRAP1 is essential for pathologic vascular changes in ischemic retinopathy

Kim, So-Yeon , Yoon, Nam Gu , Lee, Ji hye , Kim, Jaeho , Yeom, Sun A , Park, Dong Ho , Kang, Byoung Heon

Conference Paper Issue Date2023-09-21 View10

Mitochondrial chaperone TRAP1 maintains stemness properties of glioma stem cells

박혜경 , 강병헌

Conference Paper Issue Date2017-07-14 View3

Mitochondrial chaperone TRAP1 regulates ATPase inhibitory factor 1 (ATPIF1) in glioblastoma

Baek, Ji Hun , Kang, Byoung Heon

Conference Paper Issue Date2022-09-28 View6

Mitochondrial chaperone TRAP1: structure, function, and inhibitors

Kang, Byoung Heon

Conference Paper Issue Date2015-06-18 View3

Mitochondrial Chaperone, TRAP1 Regulates Anoikis Resistance and Promotes Metastatic Potential.

Sun A Yeom , Kang, Byoung Heon

Conference Paper Issue Date2023-02-22 View7

Mitochondrial Chaperone, TRAP1 Regulates GLS1 (Glutaminase 1) in Cancer Cells.

백지훈 , 염선아 , Kang, Byoung Heon

Conference Paper Issue Date2022-08-26 View3

Mitochondrial Chaperones and Cancer Drug Development

Kang, Byoung Heon

Conference Paper Issue Date2014-04-17 View4

Mitochondrial Heat Shock Protein-Guided Photodynamic Therapy File

Thomas, Ajesh P. , Lee, An-Jung , Palanikumar, L , Jana, Batakrishna , Kim, Kibeom , Kim, Sangpil , Ok, Haewon , Seol, Jihoon , Kim, Dongseok , Kang, Byoung Heon , et al

Article Issue Date2019-10 View24

Mitochondrial Hsp90s increase threshold of cell death through suppression of propagating calcium signal from mitochondria to ER

Kang, Byoung Heon , Park, Hye Kyung , Lee, Ji Eun

Conference Paper Issue Date2013 View6

Mitochondrial Hsp90s suppress calcium signals propagating from mitochondria to the ER

Kang, Byoung Heon , None

Conference Paper Issue Date2013-05-15 View5

Mitochondrial Hsp90s suppress calcium signals propagating from mitochondria to the ER

Kang, Byoung Heon

Conference Paper Issue Date2013-11-05 View3

Mitochondrial Hsp90s suppress calcium signals propagating from mitocondria to the ER

Kang, Byoung Heon , None

Conference Paper Issue Date2013 View2

Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells File File

Park, Hye-Kyung , Lee, Ji-Eun , Lim, Jaehwa , Kang, Byoung Heon

Article Issue Date2014-06 View9

Mitochondrial life or death decision in cancer cells

Kang, Byoung Heon

Conference Paper Issue Date2012 View1

Mitochondrial regulation accelerates cancer Metastasis.

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-09-29 View8

Mitochondrial Thermogenesis Can Trigger Heat Shock Response in the Nucleus File File

Kang, Myeong-Gyun , Kim, Hwa-Ryeon , Lee, Hee Yong , Kwak, Chulhwan , Koh, Hyewon , Kang, Byoung Heon , Roe, Jae-Seok , Rhee, Hyun-Woo

Article Issue Date2024-06 View27

MitoQ inactivates mitochondrial chaperone TRAP1 by interacting with the client binding site

Yoon, Nam Gu , Kang, Byoung Heon

Conference Paper Issue Date2021-12-10 View8

Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site File

Yoon, Nam Gu , Lee, Hakbong , Kim, So-Yeon , Hu, Sung , Kim, Darong , Yang, Sujae , Hong, Ki Bum , Lee, Ji Hoon , Kang, Soosung , Kim, Byung-Gyu , et al

Article Issue Date2021-12 View33

Molecular cloning, expression, and purification of nuclear inclusion A protease from tobacco vein mottling virus File

Hwang, DC , Kim, DH , Kang, Byoung Heon , Song, BD , Choi, KY

Article Issue Date2000-04 View9

Novel in vivo pan-Hsp90 family inhibitor, panvotinib-401, showed potent anticancer activities without HSF1 activation

Kang, Byoung Heon

Conference Paper Issue Date2016-04-22 View4

Novel in vivo pan-Hsp90 family protein inhibitor, Panvotinib-401, promote anticancer activities by suppressing HSF1 activity

Park, Hey-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2016-11-02 View3

Novel TRAP1 inhibitor targeting the allosteric drug binding site showed improved anti-cancer activity

Hu, Sung , Yoon, Namgu , Kang, Byoung Heon

Conference Paper Issue Date2019-06-19 View4

OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ mice File File

Yang, Yongryoul , Jang H.J. , Yoon, Sunyoung , Lee, Yonghwa , Nam, Dougu , Kim, I.S. , Lee, Heeseok , Kim, Hyun , Choi, Jang Hyun , Kang, Byoung Heon , et al

Article Issue Date2014-07 View18

Oncogenic isocitrate dehydrogenase 2 is powerfully targeted by inhibition of a mitochondrial chaperone

허성 , 강병헌

Conference Paper Issue Date2018-11-07 View7

Open and closed conformation TRAP1 crystal structures and development of a purine scaffold mitochondria-targeted Hsp90 inhibitor

Kang, Byoung Heon , None

Conference Paper Issue Date2014-10-16 View5

Overcoming Chemo-resistance through TRAP1 Inhibition Targeting High Mitochondrial Activity in Relapse/Refractory Acute Myeloid Leukemia

Hu, Sung , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-09-29 View7

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors File

Park, Hye-Kyung , Jeong, Hanbin , Ko, Eunhwa , Lee, Geumwoo , Lee, Ji-Eun , Lee, Sang Kwang , Lee, An-Jung , Im, Jin Young , Hu, Sung , Kim, Seong Heon , et al

Article Issue Date2017-09 View18

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors

Park, Hye-Kyung , Jeong, Hanbin , Ko, Eunhwa , Lee, Geunwoo , Lee, Ji-Eun , Lee, Sang Kwang , Lee, An-Jung , Lee, Jin Young , Hu, Sung , Kin, Seong Heon , et al

Conference Paper Issue Date2018-06-28 View10

PDZ Domain-containing 1 (PDZK1) Protein Regulates Phospholipase C-beta 3 (PLC-beta 3)-specific Activation of Somatostatin by Forming a Ternary Complex with PLC-beta 3 and Somatostatin Receptors File

Kim, Jung Kuk , Kwon, Ohman , Kim, Jinho , Kim, Eung-Kyun , Park, Hye Kyung , Lee, Ji Eun , Kim, Kyung Lock , Choi, Jung Woong , Lim, Seyoung , Seok, Heon , et al

Article Issue Date2012-06 View8

Possibility of metabolic control mechanism by Tumor necrosis factor receptor-associated protein 1 (TRAP1) regulating pyruvate dehydrogenase (PDH)

Lee, Anjung , Kang, Byoung Heon

Conference Paper Issue Date2017-05-18 View4

Preclinical Characterization of Mitochondria-Targeted Small Molecule Hsp90 Inhibitors, Gamitrinibs, in Advanced Prostate Cancer File

Kang, Byoung Heon , Siegelin, Markus D. , Plescia, Janet , Raskett, Christopher M. , Garlick, David S. , Dohi, Takehiko , Lian, Jane B. , Stein, Gary S. , Languino, Lucia R. , Altieri, Dario C.

Article Issue Date2010-10 View16

Pro-tumorigenic function of cancer-associated adipocytes depends on the mitochondrial chaperone, TRAP1

Yoon, Nam Gu , Kim, So-Yeon , Kong, Sun-Young , Kang, Byoung Heon

Conference Paper Issue Date2023-09-21 View6

Quaternary ammonium-based mitochondria targeting anticancer agents with high water solubility File

Kim, Sangpil , Yoon, Nam Gu , Jana, Batakrishna , Kang, Byoung Heon , Ryu, Ja-Hyoung

Article Issue Date2022-03 View21

Regulation of cell death by mitochondrial chaperone networks in cancer cells

Kang, Byoung Heon

Conference Paper Issue Date2011 View2

Regulation of cell death by mitochondrial Hsp90s

Kang, Byoung Heon

Conference Paper Issue Date2010 View2

Regulation of cellular metabolism by mitochondrial chaperone TRAP1: therapeutic opportunities

Kang, Byoung Heon

Conference Paper Issue Date2019-05-09 View9

Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein File

Kang, Byoung Heon , Altieri, Dario C.

Article Issue Date2006-08 View11

Regulation of TRAP1 and SIRT3 in glioma stem cells

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2019-06-19 View4

Regulation of tumor cell mitochondrial Homeostasis by an organelle-specific Hsp90 chaperone network File

Kang, Byoung Heon , Plescia, Janet , Dohi, Takehiko , Rosa, Jack , Doxsey, Stephen J. , Altieri, Dario C.

Article Issue Date2007-10 View7

ROS dependent HIF-1α and CypD negative feedback promotes hypoxia-induced cancer metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2021-12-10 View7

ROS dependent HIF-1α/CypD negative feedback promotes hypoxia-induced cancer metastasis.

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2021-08-25 View7

ROS regulation by Cyclophilin D contributes cancer metastasis via hypoxic signaling

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2020-10-05 View5

Simultaneous inhibition of Hsp90 family proteins promotes apoptotic cell death via calcineurin activity

Park, Hye-Kyung , Noh, Dong Yeon , Kang, Byoung Heon

Conference Paper Issue Date2017-05-18 View4

SMx inactivates mitochondrial chaperone TRAP1 by interacting with the client binding site

Yoon, Nam Gu , Kang, Byoung Heon

Conference Paper Issue Date2021-08-25 View8

SSBP1 (Single Strand DNA Binding Protein), Binds To TRAP1, A Chaperone Protein In The Mitochondria, To Maintain Mitochondrial Integrity

Lee, Ji Hye , Kang, Byoung Heon

Conference Paper Issue Date2023-11-06 View6

SSBP1, a single-strand DNA binding protein 1, maintains mitochondrial integrity by modulating the mitochondrial chaperone protein TRAP1.

Lee, Ji Hye , Kang, Byoung Heon

Conference Paper Issue Date2023-02-22 View9

Stress signal propagation from mitochondria to ER and development of combination cancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2012 View2

Structure, Function, and Inhibitors of the Mitochondrial Chaperone TRAP1 File

Kang, Soo Sung , Kang, Byoung Heon

Article Issue Date2022-12 View18

Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease File

Kang, Byoung Heon , Tavecchio, M. , Goel, H. L. , Hsieh, C. -C , Garlick, D. S. , Raskett, C. M. , Lian, J. B. , Stein, G. S. , Languino, L. R. , Altieri, D. C.

Article Issue Date2011-02 View7

Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy File File

Kim, So‐Yeon , Yoon, Nam Gu , Im, Jin Young , Lee, Ji Hye , Kim, Juhee , Jeon, Yujin , Choi, Young Jae , Lee, Jong‐Hwa , Uemura, Akiyoshi , Park, Dong Ho , et al

Article Issue Date2024-01 View536

Targeting TRAP1 in the tumor microenvironment: inhibitors and breast cancer treatment

Kang, Byoung Heon

Conference Paper Issue Date2023-10-27 View8

Temperature and salt effects on proteolytic function of turnip mosaic potyvirus nuclear inclusion protein a exhibiting a low-temperature optimum activity File

Kim, DH , Kang, Byoung Heon , Han, JS , Choi, KY

Article Issue Date2000-07 View8

The mitochondrial HSP90 TRAP1 regulate hypoxic tumor microenvironment.

Kim, So Yeon , Yoon, Nam Gu , Kang, Byoung Heon

Conference Paper Issue Date2022-02-17 View8

The mitochondrial HSP90, TRAP1 regulates hypoxic environment via stability of HIF1α.

Kim, So Yeon , Yoon, Nam Gu , Kang, Byoung Heon

Conference Paper Issue Date2022-08-26 View8

The novel resveratrol derivative 3,5-diethoxy-3', 4'-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro File

Park, Jae-woo , Choi, Woo-gyun , Lee, Phil-jun , Chung, Su-wol , Kim, Byung-sam , Chung, Hun-taeg , Cho, Sungchan , Kim, Jong-heon , Kang, Byoung Heon , Kim, Hyoungsu , et al

Article Issue Date2017-08 View21

The pro-tumorigenic role of cancer-associated adipocytes relies on the mitochondrial chaperone, TRAP1.

Yoon, Nam Gu , Kim, So-yeon , Kang, Byoung Heon

Conference Paper Issue Date2023-10-28 View5

The role of mitochondrial chaperone TRAP1 in tumorigenesis under hypoxic condition in glioblastoma

김소연 , 강병헌

Conference Paper Issue Date2018-11-07 View7

The Structure of Pro-caspase-6 is Similar to That of Active Mature Caspase-6

Kang, Byoung Heon

Conference Paper Issue Date2001-01-01 View5

THE STRUCTURE OF PRO-CASPASE-6 IS SIMILAR TO THAT OF MATURE FORM

Kang, Byoung Heon

Conference Paper Issue Date2001-01-01 View4

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