Scholarworks@UNIST: Browsing Repository

Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity File

Yang, Sujae , Yoon, Nam Gu , Kim, Dongyoung , Park, Eunsun , Kim, So-Yeon , Lee, Ji Hoon , Lee, Changwook , Kang, Byoung Heon , Kang, Soosung

Article Issue Date2021-07 View23

Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1 File

Lee, Changwook , Park, Hye-Kyung , Jeong, Hanbin , Lim, Jaehwa , Lee, An-Jung , Cheon, Keun Young , Kim, Chul-Su , Thomas, Ajesh P. , Bae, Boram , Kim, Nam Doo , et al

Article Issue Date2015-04 View19

Development of Hsp90 family protein inhibitors

Park, Hye-Kyung , Ko, Eunhwa , Lee, Geumwoo , Lee, Ji-Eun , Lee, Sang Kwang , Jeong, Hanbin , Lee, An-Jung , Im, Jin Young , Kim, Seong Heon , Lee, Changwook , et al

Conference Paper Issue Date2016-12-09 View7

Development of Hsp90 paralog specific inhibitors with mitochondrial drug delivery system

Kang, Byoung Heon

Conference Paper Issue Date2015-11-12 View3

Development of Hsp90 paralog specific inhibitors with mitochondrial drug delivery system File

Kang, Byoung Heon

Conference Paper Issue Date2015-04-18 View3

Development of Hsp90 paralog specific inhibitors with mitochondrial drug delivery system

Kang, Byoung Heon

Conference Paper Issue Date2015-04-20 View4

Development of in vivo pan-Hsp90 inhibitors as cancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2016-06-23 View4

Development of mitochondria-targeted Hsp90 inhibitor as a anti-cancer drug

Park, Hye-Jyung , Ko, Eunhwa , Lee, Gemwoo , Lee, Ji-Eun , Lee, Sang Kwang , Jeong, Hanbin , Lee, An-Jung , Im, Jing Young , Hu, Sung , Kim, Seong Heon , et al

Conference Paper Issue Date2016-11-25 View6

Development of mitochondria-targeted Hsp90 inhibitors as effective cancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2011 View4

Development of mitochondria-targeted inhibitor SMTIN-P01 and in vivo pan-Hsp90 inhibitors as cancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2015-10-15 View6

Development of mitochondria-targeted TRAP1 inhibitors and in vivo pan-Hsp90 inhibitors as cancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2015-11-20 View2

Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models File

Kim, Darong , Kim, So-Yeon , Kim, Dongyoung , Yoon, Nam Gu , Yun, Jisu , Hong, Ki Bum , Lee, Changwook , Lee, Ji Hoon , Kang, Byoung Heon , Kang, Soosung

Article Issue Date2020-08 View26

Development of small molecule inhibitors targeting the mitochondrial chaperone TRAP1 as a cancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2023-11-30 View10

Development of TRAP1 inhibitors as cancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2018-10-20 View7

Development of TRAP1 inhibitors to treat cancers and other human diseases

Kang, Byoung Heon

Conference Paper Issue Date2022-10-21 View6

Developmental Control of Apoptosis by the Immunophilin Aryl Hydrocarbon Receptor-interacting Protein (AIP) Involves Mitochondrial Import of the Survivin Protein File

Kang, Byoung Heon , Xia, Fang , Pop, Ramona , Dohi, Takehiko , Socolovsky, Merav , Altieri, Dario C.

Article Issue Date2011-05 View6

Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1 File

Jung, Sejin , Yoon, Nam Gu , Yang, Sujae , Kim, Darong , Lee, Won Seok , Hong, Ki Bum , Lee, Changwook , Kang, Byoung Heon , Lee, Ji Hoon , Kang, Soosung

Article Issue Date2020-01 View15

Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting Drug File

Hu, Sung , Ferraro, Mariarosaria , Thomas, Ajesh P. , Chung, Jeong Min , Yoon, Nam Gu , Seol, Ji-Hoon , Kim, Sangpil , Kim, Han-Ul , An, Mi Young , Ok, Haewon , et al

Article Issue Date2020-03 View11

Effects of internal cleavages and mutations in the C-terminal region of NIa protease of turnip mosaic potyvirus on the catalytic activity File

Kim, DH , Hwang, DC , Kang, Byoung Heon , Lew, J , Han, JS , Song, BOD , Choi, KY

Article Issue Date1996-12 View13

Effects of mutations in the C-terminal region of NIa protease on cis-cleavage between NIa and NIb File

Kim, DH , Han, JS , Lew, JS , Kim, SS , Kang, Byoung Heon , Hwang, DC , Jang, DS , Kim, W , Song, BD , Choi, KY

Article Issue Date1998-02 View5

Expression, Purification and Characterization of the Precursor and Mature Forms of Caspase-6

Kang, Byoung Heon

Conference Paper Issue Date2000-01-01 View7

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis File File

Choi, Sun Sil , Lee, Sang Kwon , Kim, Joong Kwan , Park, Hye-Kyung , Lee, Eujin , Jang, Jinho , Lee, Yo Han , Khim, Keon Woo , Hyun, Ji-Min , Eom, Hye-jin , et al

Article Issue Date2020-06 View28

Function of mitochondrial chaperone TRAP1 during progression of metabolic diseases

Kang, Byoung Heon

Conference Paper Issue Date2019-11-02 View7

Function of mitochondrial HSP90 in tumor angiogenesis

Kim, So Yeon , Yoon, Nam Gu , Kim, Eun Hye , Kang, Byoung Heon

Conference Paper Issue Date2020-10-08 View8

Function of mitochondrial HSP90 in tumor microenvironment

Kim, So Yeon , Yoon, Nam Gu , Kang, Byoung Heon

Conference Paper Issue Date2021-12-10 View8

Function of mitochondrial HSP90 in tumor micronenvironment

Kim, So Yeon , Yoon, Nam Gu , Kang, Byoung Heon

Conference Paper Issue Date2021-08-25 View8

Function of the mitochondrial chaperone in ischemic retinopathy.

Kim, So-Yeon , Yoon, Nam Gu , Kang, Byoung Heon , Park, Dong Ho

Conference Paper Issue Date2023-09-15 View7

Function of the mitochondrial chaperone TRAP1 in ischemic retinopathy

Kim, So Yeon , Yoon, Nam Gu , Im, Jin Young , Kim, Juhee , Jeon, Yu Jin , Choi, Young Jae , Lee, Jong-Hwa , Uemura, Akiyoshi , Kang, Byoung Heon , Park, Dong Ho

Conference Paper Issue Date2023-10-28 View7

Heat shock protein 60 (HSP60) interact with glutaryl co-a dehydrogenase (GCDH)

Kang, Byoung Heon , None

Conference Paper Issue Date2013 View6

Hepatoprotective and antineoplastic properties of Protaetia brevitarsis larvae File

Lee, Ji-Eun , Jo, Da-Eun , Lee, An-Jung , Park, Hye-Kyung , Youn, Kumju , Yun, Eun-Young , Hwang, Jae-Sam , Jun, Mira , Kang, Byoung Heon

Article Issue Date2014-11 View8

HIF-1α/CypD Negative Regulation Accelerates Hypoxia-induced Cancer Metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-02-17 View8

Hsp60 regulation of tumor cell apoptosis File

Ghosh, Jagadish C. , Dohi, Takehiko , Kang, Byoung Heon , Altieri, Dario C.

Article Issue Date2008-02 View8

Inhibition studies on the nuclear inclusion protein a protease of turnip mosaic potyvirus C5

Kim, DH , Kang, Byoung Heon , Hwang, DC , Kim, SS , Kwon, TI , Choi, KY

Article Issue Date1996-12 View8

Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells File

Park, Hye-Kyung , Hong, Jun-Hee , Oh, Young Taek , Kim, Sung Soo , Yin, Jinlong , Lee, An-Jung , Chae, Young Chan , Kim, Jong Heon , Park, Sung-Hye , Park, Chul-Kee , et al

Article Issue Date2019-04 View11

Loops of HIF1a and Cyclophilin D promote cancer netastasis through long-term ROS signaling.

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2020-10-08 View7

Microenvironment-adapted mitochondria promote metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2023-05-08 View5

Mitochondria adapted to the microenvironment of primary tumors promote cancer metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2023-06-16 View4

Mitochondria target therapy through inhibition TRAP1-IDH2 to treat relapse/refractory acute myeloid leukemia

Sung Hu , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-02-16 View7

Mitochondria target therapy through inhibition TRAP1-IDH2 to treat relapse/refractory AML

Hu, Sung , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-08-26 View11

Mitochondria-ER crosstalk and combination cancer therapy

Kang, Byoung Heon

Conference Paper Issue Date2012 View1

Mitochondria-targeted Hsp90 inhibitors as novel anticancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2011 View1

Mitochondria-targeted Hsp90 inhibitors as novel anticancer therapeutics

Kang, Byoung Heon

Conference Paper Issue Date2010 View2

Mitochondrial Chaperone Protein, TRAP1 Modulates Mitochondrial Integrity by Regulating SSBP1(Single- Strand DNA Binding Protein 1).

Lee, JH , Kim, SY , Kang, Byoung Heon

Conference Paper Issue Date2022-08-26 View5

Mitochondrial Chaperone Protein, TRAP1 Modulates Mitochondrial Integrity by Regulating SSBP1(Single- Strand DNA Binding Protein 1).

Lee, JH , Kim, SY , Kang, Byoung Heon

Conference Paper Issue Date2022-02-16 View8

Mitochondrial chaperone TRAP1 and mitochondria-targeted inhibitor development

Kang, Byoung Heon

Conference Paper Issue Date2015-09-18 View5

Mitochondrial chaperone TRAP1 in human disease progression

Kang, Byoung Heon

Conference Paper Issue Date2022-09-28 View6

Mitochondrial chaperone TRAP1 is essential for pathologic vascular changes in ischemic retinopathy

Kim, So-Yeon , Yoon, Nam Gu , Lee, Ji hye , Kim, Jaeho , Yeom, Sun A , Park, Dong Ho , Kang, Byoung Heon

Conference Paper Issue Date2023-09-21 View10

Mitochondrial chaperone TRAP1 maintains stemness properties of glioma stem cells

박혜경 , 강병헌

Conference Paper Issue Date2017-07-14 View3

Mitochondrial chaperone TRAP1 regulates ATPase inhibitory factor 1 (ATPIF1) in glioblastoma

Baek, Ji Hun , Kang, Byoung Heon

Conference Paper Issue Date2022-09-28 View6

Mitochondrial chaperone TRAP1: structure, function, and inhibitors

Kang, Byoung Heon

Conference Paper Issue Date2015-06-18 View1

Mitochondrial Chaperone, TRAP1 Regulates Anoikis Resistance and Promotes Metastatic Potential.

Sun A Yeom , Kang, Byoung Heon

Conference Paper Issue Date2023-02-22 View7

Mitochondrial Chaperone, TRAP1 Regulates GLS1 (Glutaminase 1) in Cancer Cells.

백지훈 , 염선아 , Kang, Byoung Heon

Conference Paper Issue Date2022-08-26 View3

Mitochondrial Chaperones and Cancer Drug Development

Kang, Byoung Heon

Conference Paper Issue Date2014-04-17 View3

Mitochondrial Heat Shock Protein-Guided Photodynamic Therapy File

Thomas, Ajesh P. , Lee, An-Jung , Palanikumar, L , Jana, Batakrishna , Kim, Kibeom , Kim, Sangpil , Ok, Haewon , Seol, Jihoon , Kim, Dongseok , Kang, Byoung Heon , et al

Article Issue Date2019-10 View23

Mitochondrial Hsp90s increase threshold of cell death through suppression of propagating calcium signal from mitochondria to ER

Kang, Byoung Heon , Park, Hye Kyung , Lee, Ji Eun

Conference Paper Issue Date2013 View6

Mitochondrial Hsp90s suppress calcium signals propagating from mitochondria to the ER

Kang, Byoung Heon , None

Conference Paper Issue Date2013-05-15 View4

Mitochondrial Hsp90s suppress calcium signals propagating from mitochondria to the ER

Kang, Byoung Heon

Conference Paper Issue Date2013-11-05 View3

Mitochondrial Hsp90s suppress calcium signals propagating from mitocondria to the ER

Kang, Byoung Heon , None

Conference Paper Issue Date2013 View2

Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells File File

Park, Hye-Kyung , Lee, Ji-Eun , Lim, Jaehwa , Kang, Byoung Heon

Article Issue Date2014-06 View9

Mitochondrial life or death decision in cancer cells

Kang, Byoung Heon

Conference Paper Issue Date2012 View1

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