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A combination of direct reversion and nucleotide excision repair counters the mutagenic effects of DNA carboxymethylation File

Aloisi, Claudia M. N. , Escher, Nora A. , Kim, Hyun Suk , Geisen, Susanne M. , Fontana, Gabriele A. , Yeo, Jung-Eun , Scharer, Orlando D. , Sturla, Shana J.

Article Issue Date2022-02 View161

A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair File File

van den Heuvel, Diana , Kim, Mihyun , Wondergem, Annelotte P. , van der Meer, Paula J. , Witkamp, Myrèse , Lambregtse, Ferdy , Kim, Hyun-Suk , Kan, Folkert , Apelt, Katja , Kragten, Angela , et al

Article Issue Date2023-03 View130

A molecular basis for damage recognition in eukaryotic nucleotide excision repair File

Schaerer, Orlando D.

Article Issue Date2008-01 View149

A Splicing Variant in XPA Results in Delayed Onset of Clinical Features of Xeroderma Pigmentosum File File

van den Heuvel, Anita , Wondergem, Annelotte P. , Kim, Mihyun , Breet, Isa , Kim, Hyun-suk , Fawcett, Heather D. , Fassihi, Hiva , Lehmann, Alan Robert , Schärer, Orlando D. , Luijsterburg, Martijn S.

Article Issue Date2026-04 View18

Analysis of mutational signatures in C. elegans: Implications for cancer genome analysis File

Meier, Bettina , Volkova, Nadezda V. , Gerstung, Moritz , Gartner, Anton

Article Issue Date2020-11 View142

Caenorhabditis elegans NSE3 homolog (MAGE-1) is involved in genome stability and acts in inter-sister recombination during meiosis File

Odiba, Arome Solomon , Liao, Guiyan , Ezechukwu, Chiemekam Samuel , Zhang, Lanlan , Hong, Ye , Fang, Wenxia , Jin, Cheng , Gartner, Anton , Wang, Bin

Article Issue Date2023-10 View136

DNA damage response inhibitors in cancer therapy: Mechanisms, clinical development, and combination strategies File

Lee, Seon-gyeong , Kim, Jinwoo , Jeong, Euihwan , Myung, Kyungjae

Article Issue Date2025-09 View92

DNA repair, recombination, and damage signaling File File

Gartner, Anton , Engebrecht, JoAnne

Article Issue Date2022-02 View134

Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair File File

Tsutakawa, Susan E. , Tsai, Chi-Lin , Yan, Chunli , Bralic, Amer , Chazin, Walter J. , Hamdan, Samir M. , Scharer, Orlando D. , Ivanov, Ivaylo , Tainer, John A.

Article Issue Date2020-12 View155

Genetic analysis of ionizing radiation-induced mutagenesis in Saccharomyces cerevisiae reveals TransLesion Synthesis (TLS) independent of PCNA K164SUMOylation and ubiquitination File

Chen, Clark C. , Motegi, Akira , Hasegawa, Yuko , Myung, Kyungjae , Kolodner, Richard , D'Andrea, Alan

Article Issue Date2006-12 View82

Germ Cell Apoptosis and DNA Damage Responses File

Bailly, Aymeric , Gartner, Anton

Article Issue Date2013-20 View88

KARP-1: A novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity File

Myung, K , He, DM , Lee, SE , Hendrickson, EA

Article Issue Date1997-06 View107

Large-scale generation and phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes File

Shin, Unbeom , Nakhro, Khriezhanuo , Oh, Chang-Kyu , Carrington, Blake , Song, HeaIn , Varshney, Gaurav K. , Kim, Yeongjae , Song, Hyemin , Jeon, Sangeun , Robbins, Gabrielle , et al

Article Issue Date2021-11 View106

MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers File File

Srinivasan, Gayathri , Williamson, Elizabeth A. , Kong, Kimi , Jaiswal, Aruna S. , Huang, Guangcun , Kim, Hyun-Suk , Scharer, Orlando D. , Zhao, Weixing , Burma, Sandeep , Sung, Patrick , et al

Article Issue Date2019-08 View138

Mre11-Rad50-Nbs1 complex is activated by hypertonicity File

Sheen, Mee Rie , Kim, Seung Whan , Jung, Ju-Young , Ahn, Joon Young , Rhee, Juong G. , Kwon, H. Moo , Woo, Seung Kyoon

Article Issue Date2006-11 View214

PARP1-mediated PARylation of TonEBP prevents R-loop-associated DNA damage File

Ye, Byeong Jin , Kang, Hyun Je , Lee-Kwon, Whaseon , Kwon, Hyug Moo , Choi, Soo Youn

Article Issue Date2021-08 View179

Protein-protein interactions in the core nucleotide excision repair pathway File

D'Souza, Areetha , Kim, Mihyun , Chazin, Walter J. , Scharer, Orlando D.

Article Issue Date2024-09 View158

RAD18-BRCTx interaction is required for efficient repair of UV-induced DNA damage File

Liu, Ting , Chen, Hongxia , Kim, Hongtai , Huen, Michael S. Y. , Chen, Junjie , Huang, Jun

Article Issue Date2012-02 View117

SMC-5/6 complex subunit NSE-1 plays a crucial role in meiosis and DNA repair in Caenorhabditis elegans File

Odiba, Arome Solomon , Ezechukwu, Chiemekam Samuel , Liao, Guiyan , Hong, Ye , Fang, Wenxia , Jin, Cheng , Gartner, Anton , Wang, Bin

Article Issue Date2024-05 View7

Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA File

Tsodikov, Oleg V. , Ivanov, Dmitri , Orelli, Barbara , Staresincic, Lidija , Shoshani, Ilana , Oberman, Robert , Scharer, Orlando D. , Wagner, Gerhard , Ellenberger, Tom

Article Issue Date2007-11 View113

Structural mechanism of DNA interstrand cross-link unhooking by the bacterial FAN1 nuclease File

Jin, Hyeonseok , Roy, Upasana , Lee, Gwangrog , Scharer, Orlando D. , Cho, Yunje

Article Issue Date2018-04 View79

Suppression of gross chromosomal rearrangements by yKu70-yKu80 heterodimer through DNA damage checkpoints File

Banerjee, S , Smith, S , Myung, K

Article Issue Date2006-02 View151

The complexity and regulation of repair of alkylation damage to nucleic acids File

Tsao, Ning , Scharer, Orlando D. , Mosammaparast, Nima

Article Issue Date2021-03 View110

Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair File

Kim, Mihyun , Kim, Hyun-Suk , D'Souza, Areetha , Gallagher, Kaitlyn , Jeong, Eunwoo , Le Meur, Kateryna Ogorodnik , Tsai, Chi-Lin , Tsai, Miaw-Sheue , Kee, Minyong , Tainer, John A. , et al

Article Issue Date2022-08 View121

Unraveling DNA Repair Processes In Vivo: Insights from Zebrafish Studies File

Shin, Unbeom , Lee, Yoonsung

Article Issue Date2023-09 View113

When DNA Repair Backfires - Trabectedin Induces DNA Breaks in Active Genes File

Takhaveev, Vakil , Son, Kook , Mor, Visesato , Yu, Hobin , Dillier, Emma , Zilio, Nicola , Pullen, J. L. , Ivanov, Dmitri , Ulrich, Helle D. , Sturla, Shana J. , et al

Article Issue Date2025-04 View119

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