Scholarworks@UNIST: Browsing Repository

A near-infrared fluorescent probe for amyloid-β aggregates File

Lee, Misun , Kim, Mingeun , Tikum, Anjong Florence , Lee, Hyuck Jin , Thamilarasan, Vijayan , Lim, Mi Hee , Kim, Jinheung

Article Issue Date2019-03 View5

A rationally designed small molecule for identifying an in vivo link between metal-amyloid-β complexes and the pathogenesis of Alzheimer's disease File File

Beck, Michael W. , Oh, Shin Bi , Kerr, Richard A. , Lee, Hyuck Jin , Kim, So Hee , Kim, Sujeong , Jang, Milim , Ruotolo, Brandon T. , Lee, Joo-Yong , Lim, Mi Hee

Article Issue Date2015-03 View4

A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms File

Derrick, Jeffrey S. , Kerr, Richard A. , Nam, Younwoo , Oh, Shin Bi , Lee, Hyuck Jin , Earnest, Kaylin G. , Suh, Nayoung , Peck, Kristy L. , Ozbil, Mehmet , Korshavn, Kyle J. , et al

Article Issue Date2015-11 View4

A small molecule that displays marked reactivity toward copper-versus zinc-amyloid-β implicated in Alzheimer's disease File

Savelieff, Masha G. , Liu, Yuzhong , Senthamarai, Russell R. P. , Korshavn, Kyle J. , Lee, Hyuck Jin , Ramamoorthy, Ayyalusamy , Lim, Mi Hee

Article Issue Date2014-05 View4

AN IRIDIUM(III) COMPLEX AS A PHOTOACTIVATABLE TOOL FOR OXIDATION OF AMYLOIDOGENIC PEPTIDES WITH SUBSEQUENT MODULATION OF PEPTIDE AGGREGATION

Kang, Juhye , Lee, Shin Jung C , Nam, Jung Seung , Lee, Hyuck Jin , Korshavn, Kyle J. , Kim, Hyun-Tak , Cho, Jaeheung , Ramamoorthy, Ayyalusamy , Rhee, Hyun-Woo , Kwon, Tae-Hyuk , et al

Conference Paper Issue Date2016-12-05 View3

An Iridium(III) Complex as a Photoactivatable Tool for Oxidation of Amyloidogenic Peptides with Subsequent Modulation of Peptide Aggregation File

Kang, Juhye , Lee, Shin Jung C. , Nam. Jung Seung , Lee, Hyuck Jin , Kang, Mueong-G. , Korshavn, Kyle J. , Kim, Hyun-Tak , Cho, Jaeheung , Ramamoorthy, Ayyalusamy , Rhee, Hyun-Woo , et al

Article Issue Date2017-01 View8

Calprotectin influences the aggregation of metal-free and metal-bound amyloid- beta by direct interaction File

Lee, Hyuck Jin , Savelieff, Masha G. , Kang, Juhye , Brophy, Megan Brunjes , Nakashige, Toshiki G. , Lee, Shin Jung C. , Nolan, Elizabeth M. , Lim, Mi Hee

Article Issue Date2018-08 View2

Chemical Regulators Containing Two Redox-Active Structural Moieties against Multiple Pathogenic Features in Alzheimer’s Disease

Han, Jiyeon , Lee, Hyuck Jin , Kim, Kyu Yeon , Lee, Shin Jung C. , Cho, Jaeheung , Chae, Junghyun , Lim, Mi Hee

Conference Paper Issue Date2017-07-19 View3

Chemical strategies to modify amyloidogenic peptides using iridium(III) complexes: coordination and photo-induced oxidation File File

Kang, Juhye , Nam, Jung Seung , Lee, Hyuck Jin , Nam, Geewoo , Rhee, Hyun-Woo , Kwon, Tae-Hyuk , Lim, Mi Hee

Article Issue Date2019-07 View4

Cholesterol and metal ions in Alzheimer's disease File

Lee, Hyuck Jin , Korshavn, Kyle J. , Kochi, Akiko , Derrick, Jeffrey S. , Lim, Mi Hee

Article Issue Date2014-10 View5

Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade File

Savelieff, Masha G. , Nam, Geewoo , Kang, Juhye , Lee, Hyuck Jin , Lee, Misun , Lim, Mi Hee

Article Issue Date2019-01 View3

Effects of Variable Hydroxyl Groups on the Flavonoid Backbone toward Modulation of Metal–Amyloid-Beta Aggregation Pathways

Lim, Mi Hee , Lee, Hyuck Jin , Kerr, Richard A. , Korshavn, Kyle J. , Lee, Jeeyeon , Ramamoorthy, Ayyalusamy , Ruotolo, Brandon T.

Conference Paper Issue Date2015-08-12 View1

Flavonoids: Redirection of Metal-Free and Metal-Associated Amyloid-b Aggregation Into Nontoxic, Off-Pathway Amorphous Peptide Aggregates

Lim, Mi Hee , DeToma, Alaina S. , Lee, Hyuck Jin , Lee, Jeeyeon

Conference Paper Issue Date2014-12-01 View3

Impact of sphingosine and acetylsphingosines on the aggregation and toxicity of metal-free and metal-treated amyloid-beta File

Yi, Yelim , Lin, Yuxi , Han, Jiyeon , Lee, Hyuck Jin , Park, Nahye , Nam, Geewoo , Park, Young S. , Lee, Young-Ho , Lim, Mi Hee

Article Issue Date2021-02 View7

Inhibitory activity of curcumin derivatives towards metal-free and metal-induced amyloid-β aggregation File

Kochi, Akiko , Lee, Hyuck Jin , Vithanarachchi, Sashiprabha M. , Padmini, Vediappen , Allen, Matthew J. , Lim, Mi Hee

Article Issue Date2015-05 View6

Interaction and reactivity of synthetic aminoisoflavones with metal-free and metal-associated amyloid-β File

Detoma, Alaina S. , Krishnamoorthy, Janarthanan , Nam, Younwoo , Lee, Hyuck Jin , Brender, Jeffrey R. , Kochi, Akiko , Lee, Dongkuk , Onnis, Valentina , Congiu, Cenzo , Manfredini, Stefano , et al

Article Issue Date2014-12 View6

Mechanistic approaches for chemically modifying the coordination sphere of copper-amyloid-beta complexes File

Han, Jiyeon , Lee, Hyuck Jin , Kim, Kyu Yeon , Nam, Geewoo , Chae, Junghyun , Lim, Mi Hee

Article Issue Date2020-03 View4

Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia File

Kim, Mingeun , Kang, Juhye , Lee, Misun , Han, Jiyeon , Nam, Geewoo , Tak, Eunyoung , Kim, Min Sun , Lee, Hyuck Jin , Nam, Eunju , Park, Jiyong , et al

Article Issue Date2020-05 View5

Molecular Insights into Human Serum Albumin as a Receptor of Amyloid-β in the Extracellular Region File

Choi, Tae Su , Lee, Hyuck Jin , Han, Jong Yoon , Lim, Mi Hee , Kim, Hugh I.

Article Issue Date2017-11 View3

Monitoring metal–amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening File File

Lee, Hyuck Jin , Lee, Young Geun , Kang, Juhye , Yang, Seung Hyun , Kim, Ju Hwan , Ghisaidoobe, Amar B. T. , Kang, Hyo Jin , Lee, Sang-Rae , Lim, Mi Hee , Chung, Sang J.

Article Issue Date2019-01 View4

Multiple reactivities of flavonoids towards pathological elements in Alzheimer's disease: structure-activity relationship File

Nam, Geewoo , Hong, Mannkyu , Lee, Juri , Lee, Hyuck Jin , Ji, Yonghwan , Kang, Juhye , Baik, Mu-Hyun , Lim, Mi Hee

Article Issue Date2020-10 View1

Orobol: An Isoflavone Exhibiting Regulatory Multifunctionality against Four Pathological Features of Alzheimer's Disease File

Nam, Geewoo , Ji, Yonghwan , Lee, Hyuck Jin , Kang, Juhye , Yi, Yelim , Kim, Mingeun , Lin, Yuxi , Lee, Young-Ho , Lim, Mi Hee

Article Issue Date2019-08 View3

Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease File

Lee, Sanghyun , Zheng, Xueyun , Krishnamoorthy, Janarthanan , Savelieff, Masha G. , Park, Hyun Min , Brender, Jeffrey R. , Kim, Jin Hoon , Derrick, Jeffrey S. , Kochi, Akiko , Lee, Hyuck Jin , et al

Article Issue Date2014-01 View5

Redox-tuning of Small Molecules to Develop Chemical Regulators for Multiple Pathogenic Elements in Alzheimer’s Disease

Han, Jiyeon , Lee, Hyuck Jin , Cho, Jaeheung , Chae, Junghyun , Lim, Mi Hee

Conference Paper Issue Date2017-10-18 View3

Redox-tuning of Small Molecules to Develop Chemical Regulators for Multiple Pathogenic Elements in Alzheimer’s Disease

Han, Jiyeon , Lee, Hyuck Jin , Cho, Jaeheung , Chae, Junghyun , Lim, Mi Hee

Conference Paper Issue Date2017-10-19 View4

Strategic Design of 2,2 '-Bipyridine Derivatives to Modulate Metal Amyloid-beta Aggregation File

Ji, Yonghwan , Lee, Hyuck Jin , Kim, Munjeong , Nam, Geewoo , Lee, Shun Jung C. , Cho. Jaeheung , Park, Cheol-Min , Lim, Mi Hee

Article Issue Date2017-06 View8

Strategic Design of 2,2’-Bipyridine Derivatives to Modulate Metal-Amyloid-β Aggregation

Ji, Yongwhan , Lee, Hyuck Jin , Cho, Jaeheung , Park, Cheol-Min , Lim, Mi Hee

Conference Paper Issue Date2017-10-19 View3

Strategic Design of 2,2’-Bipyridine Derivatives to Modulate Metal–Amyloid-beta Aggregation

Ji, Yonghwan , Lee, Hyuck Jin , Kim, Minjeong , Nam, Geewoo , Lee, Shin Jung C. , Cho, Jaeheung , Park, Cheol-Min , Lim, Mi Hee

Conference Paper Issue Date2017-07-19 View3

Strategic Design of 2,2’-Bipyridine Derivatives to Modulate Metal–Amyloid-beta Aggregation

Ji, Yonghwan , Lee, Hyuck Jin , Kim, Minjeong , Nam, Geewoo , Lee, Shin Jung C. , Cho, Jaeheung , Park, Cheol-Min , Lim, Mi Hee

Conference Paper Issue Date2017-08-16 View3

Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer’s Disease

Lee, Hyuck Jin , Korshavn, Kyle J , Nam, Younwoo , Paul, Thomas J. , Kerr, Richard A , Youn, Il Seung , Kang, Juhye , Ozbil, Mehmet , Kim, Kwang S. , Ruotolo, Brandon T , et al

Conference Paper Issue Date2017-08-16 View3

Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer’s Disease

Lee, Hyuck Jin , Korshavn, Kyle J. , Nam, Younwoo , Paul, Thomas J. , Kerr, Richard A. , Youn, Il Seung , Kang, Juhye , Ozbil, Mehmet , Kim, Kwang S. , Ruotolo, Brandon T. , et al

Conference Paper Issue Date2017-07-19 View0

Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-related Pathological Features in Alzheimer’s Disease File

Lee, Hyuck Jin , Korshavn, Kyle J. , Nam, Younwoo , Kang, Juhye , Paul, Thomas J. , Kerr, Richard A. , Youn, Il Seung , Ozbil, Mehmet , Kim, Kwang S. , Ruotolo, Brandon T. , et al

Article Issue Date2017-02 View3

Structure and assembly mechanisms of toxic human islet amyloid polypeptide oligomers associated with copper File File

Lee, Shin Jung C. , Choi, Tae Su , Lee, Jong Wha , Lee, Hyuck Jin , Mun, Dong-Gi , Akasi, Satoko , Lee, Sang-Won , Lim, Mi Hee , Kim, Hugh I.

Article Issue Date2016-08 View1

Tailoring Hydrophobic Interactions between Probes and Amyloid-β Peptides for Fluorescent Monitoring of Amyloid-β Aggregation File

Kim, Sonam , Lee, Hyuck Jin , Nam, Eunju , Jeong, Donghyun , Cho, Jaeheung , Lim, Mi Hee , You, Youngmin

Article Issue Date2018-05 View5

The Variation of Hydroxyl Groups on the Flavonoid Backbone Directs the Modulation of Cu(II)–Aβ Aggregation Pathways

Lim, Mi Hee , Lee, Hyuck Jin , Richard A. Kerr2, , Kyle J. Korshavn2, , Lee, Jeeyeon , A. Ramamoorthy , Brandon T. Ruotolo

Conference Paper Issue Date2015-09-12 View2

Towards an understanding of amyloid-beta oligomers: characterization, toxicity mechanisms, and inhibitors File

Lee, Shin Jung C. , Nam, Eunju , Lee, Hyuck Jin , Savelieff, Masha G. , Lim, Mi Hee

Article Issue Date2017-01 View3

Tuning Structures and Properties for Developing Novel Chemical Tools toward Distinct Pathogenic Elements in Alzheimer's Disease File

Han, Jiyeon , Lee, Hyuck Jin , Kim, Kyu Yeon , Lee, Shin Jung C. , Suh, Jong-Min , Cho, Jaeheung , Chae, Junghyun , Lim, Mi Hee

Article Issue Date2018-04 View5

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