BROWSE

Related Researcher

Author's Photo

Lim, Mi Hee
MetalloNeuroChemistry Lab (MNCL)
Research Interests
  • Neurodegenerative disease, small molecule design, network between metal, proteins, and ROS

ITEM VIEW & DOWNLOAD

A small molecule that displays marked reactivity toward copper-versus zinc-amyloid-β implicated in Alzheimer's disease

Cited 3 times inthomson ciCited 2 times inthomson ci
Title
A small molecule that displays marked reactivity toward copper-versus zinc-amyloid-β implicated in Alzheimer's disease
Author
Savelieff, Masha G.Liu, YuzhongSenthamarai, Russell R. P.Korshavn, Kyle J.Lee, Hyuck JinRamamoorthy, AyyalusamyLim, Mi Hee
Issue Date
2014-05
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.50, no.40, pp.5301 - 5303
Abstract
Alzheimer's disease (AD) is a complex, multifactorial, neurodegenerative disease that poses tremendous difficulties in pinpointing its precise etiology. A toolkit, which specifically targets and modulates suggested key players, may elucidate their roles in disease onset and progression. We report high-resolution insights on the activity of a small molecule (L2-NO) which exhibits reactivity toward Cu(II)-amyloid-β (Aβ) over Zn(II)-Aβ.
URI
https://scholarworks.unist.ac.kr/handle/201301/4500
URL
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84899083584
DOI
10.1039/c3cc48473d
ISSN
1359-7345
Appears in Collections:
PHY_Journal Papers
Files in This Item:
There are no files associated with this item.

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU