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A chemical tool for blue light-inducible proximity photo-crosslinking in live cells File

Mishra, Pratyush Kumar , Kang, Myeong-Gyun , Lee, Hakbong , Kim, Seungjoon , Choi, Subin , Sharma, Nirmali , Park, Cheol-Min , Ko, Jaewon , Lee, Changwook , Seo, Jeong Kon , et al

Article Issue Date2022-01 View35

A novel TRAP1 inhibitor, UB-010 potently inactivates the mitochondrial chaperoneby interacting with the client binding site.

Yoon, Nam Gu , Hu, Sung , Kim. So-Yeon , Lee, Changwook , Kang, Byoung Heon

Conference Paper Issue Date2020-10-08 View11

Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance File

Sim, Hyo Jung , Cho, Chanmi , Kim, Ha Eun , Hong, Ju Yeon , Song, Eun Kyung , Kwon, Keun Yeong , Jang, Dong Gil , Kim, Seok-Jung , Lee, Changwook , Lee, Hyun-Shik , et al

Article Issue Date2022-01 View16

Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy File File

Kwon, Jiwoong , Park, Jong-Seok , Kang, Minsu , Choi, Soobin , Park, Jumi , Kim, Gyeong Tae , Lee, Changwook , Cha, Sangwon , Rhee, Hyun-Woo , Shim, Sang-Hee

Article Issue Date2020-01 View15

Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex

Jeong, Hanbin , Park, Jumi , Lee, Changwook

Conference Paper Issue Date2017-10-18 View14

Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex File

Jeong, Hanbin , Park, Jumi , Lee, Changwook

Article Issue Date2016-12 View14

Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway File File

Jeong, Hanbin , Sim, Hyo Jung , Song, Eun Kyung , Lee, Hakbong , Ha, Sung Chul , Jun, Youngsoo , Park, Tae Joo , Lee, Changwook

Article Issue Date2016-02 View14

Crystal Structures of Mmm1 and Mdm12-Mmm1 Reveal Mechanistic Insight into Phospholipid Trafficking at ER-Mitochondria Contact Sites

Jeong, Hanbin , Park, Jumi , Jun, Youngsoo , Lee, Changwook

Conference Paper Issue Date2018-01-04 View9

Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites File

Jeong, Hanbin , Park, Jumi , Jun, Youngsoo , Lee, Changwook

Article Issue Date2017-11 View16

Crystallization and preliminary X-ray diffraction analysis of the Sel1-like repeats of SEL1L File

Jeong, Hanbin , Lee, Hakbong , Lee, Changwook

Article Issue Date2014-12 View19

Crystallization and preliminary X-ray diffraction analysis of Trap1 complexed with Hsp90 inhibitors File

Kang, Byoung Heon , Jeong, Hanbin , Lee, Changwook

Article Issue Date2014-12 View18

Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity File

Yang, Sujae , Yoon, Nam Gu , Kim, Dongyoung , Park, Eunsun , Kim, So-Yeon , Lee, Ji Hoon , Lee, Changwook , Kang, Byoung Heon , Kang, Soosung

Article Issue Date2021-07 View27

Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human Trap1

Lee, Changwook

Conference Paper Issue Date2015-09-16 View7

Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1 File

Lee, Changwook , Park, Hye-Kyung , Jeong, Hanbin , Lim, Jaehwa , Lee, An-Jung , Cheon, Keun Young , Kim, Chul-Su , Thomas, Ajesh P. , Bae, Boram , Kim, Nam Doo , et al

Article Issue Date2015-04 View27

Development of Hsp90 family protein inhibitors

Park, Hye-Kyung , Ko, Eunhwa , Lee, Geumwoo , Lee, Ji-Eun , Lee, Sang Kwang , Jeong, Hanbin , Lee, An-Jung , Im, Jin Young , Kim, Seong Heon , Lee, Changwook , et al

Conference Paper Issue Date2016-12-09 View8

Development of mitochondria-targeted Hsp90 inhibitor as a anti-cancer drug

Park, Hye-Jyung , Ko, Eunhwa , Lee, Gemwoo , Lee, Ji-Eun , Lee, Sang Kwang , Jeong, Hanbin , Lee, An-Jung , Im, Jing Young , Hu, Sung , Kim, Seong Heon , et al

Conference Paper Issue Date2016-11-25 View6

Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models File

Kim, Darong , Kim, So-Yeon , Kim, Dongyoung , Yoon, Nam Gu , Yun, Jisu , Hong, Ki Bum , Lee, Changwook , Lee, Ji Hoon , Kang, Byoung Heon , Kang, Soosung

Article Issue Date2020-08 View32

Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1 File

Jung, Sejin , Yoon, Nam Gu , Yang, Sujae , Kim, Darong , Lee, Won Seok , Hong, Ki Bum , Lee, Changwook , Kang, Byoung Heon , Lee, Ji Hoon , Kang, Soosung

Article Issue Date2020-01 View23

Ergosterol interacts with Sey1p to promote atlastin-mediated endoplasmic reticulum membrane fusion in Saccharomyces cerevisiae File

Lee, Miriam , Moon, Yeojin , Lee, Sanghwa , Lee, Changwook , Jun, Youngsoo

Article Issue Date2019-03 View16

GEN-Click: Genetically Encodable Click Reactions for Spatially Restricted Metabolite Labeling File

Mishra, Pratyush Kumar , Sharma, Nirmali , Kim, Hyunwoo , Lee, Changwook , Rhee, Hyun-Woo

Article Issue Date2023-08 View30

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