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남덕우
Nam, Dougu

남덕우

생명과학과

Research Interests
Bioinformatics;Genomics;Systems biology;Single-cell data;Transcriptomics;GWAS;microRNA
Lab Description
We are bioinformatics group at UNIST.
Our research interests are as follows:(1) Identifying molecular markers and their functional networks that are associated with disease by analyzing transcriptomic and genomic data(2) Developing computational models and algorithms that impact bio-medical research(3) Classifying disease subtypes or cell types using gene expression big data (microarray, RNA-seq, single cell)
To this aim, we analyze microarrays, RNA-seq, GWAS, and single cell data in an integrative manner.We also use and develop machine learning methods for data processing, clustering, dimension reduction, and classification.
Current Topics of Interest:Development of single-cell data processing, clustering, and classification methodsBiclustering analysis of transcriptome big dataPathway and network analysis of gene expression and GWAS dataDetection of rare drivers in cancer by integrating mutation and expressionRead count modeling and simulation of RNA-seq and single cell dataImproving miRNA target prediction
Researcher ID Research Gate ORCiD Scopus Google Scholar
Previous
Hepatic miR-93 promotes the pathogenesis of metabolic dysfunction-associated steatotic liver disease by suppressing SIRT1 File

Lee, Yo Han , Lee, Jinyoung , Jeong, Joonho , Park, Kieun , Baik, Bukyung , Kwon, Yuseong , Kim, Kimyeong , Khim, Keon Woo , Ji, Haneul , Lee, Ji Young , et al

Article Issue Date2025-08 View167
Pseudohypoxic stabilization of HIF1α via cyclophilin D suppression promotes melanoma metastasis File

Park, Hye-Kyung , Hu, Sung , Kim, So Yeon , Yoon, Sora , Yoon, Nam Gu , Lee, Ji Hye , Choi, Wonyoung , Kong, Sun-Young , Kim, Jong Heon , Nam, Dougu , et al

Article Issue Date2025-07 View127
Dynamic and reversible transcriptomic age shifts induced by COVID-19 in Korean whole blood File File

An, Kyungwhan , Kwon, Yoonsung , Bhak, Jihun , Ryu, Hyojung , Jeon, Sungwon , Nam, Dougu , Bhak, Jong

Article Issue Date2025-06 View32
Restored streams recover food web properties but with different scaling relationships when compared with natural streams File

Lee, Minyoung , Kim, Yongeun , Nam, Dougu , Cho, Kijong

Article Issue Date2025-03 View165
Characterizing efficient feature selection for single-cell expression analysis File

Cho, Juok , Baik, Bukyung , Nguyen, Hai C. T. , Park, Daeui , Nam, Dougu

Article Issue Date2024-07 View123
Impacts of the accumulated extinction of endangered species on stream food webs File File

Lee, Minyoung , Kim, Yongeun , Nam, Dougu , Cho, Kijong

Article Issue Date2023-12 View164
Benchmarking integration of single-cell differential expression File File

Nguyen, Hai C. T. , Baik, Bukyung , Yoon, Sora , Park, Taesung , Nam, Dougu

Article Issue Date2023-03 View134
MicroRNA-29 Ameliorates Fibro-Inflammation and Insulin Resistance in HIF1α-Deficient Obese Adipose Tissue by Inhibiting Endotrophin Generation File

Jo, Woobeen , Kim, Min , Oh, Jiyoung , Kim, Chu-Sook , Park, Chanho , Yoon, Sora , Lee, Changhu , Kim, Sahee , Nam, Dougu , Park, Jiyoung

Article Issue Date2022-08 View190
Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA File

Lee, Yo Han , Jang, Hyun-Jun , Kim, Sounkou , Choi, Sun Sil , Khim, Keon Woo , Eom, Hye-Jin , Hyun, Jimin , Shin, Kyeong Jin , Chae, Young Chan , Kim, Hongtae , et al

Article Issue Date2021-12 View202
Powerful p-value combination methods to detect incomplete association File File

Yoon, Sora , Baik, Bukyung , Park, Taesung , Nam, Dougu

Article Issue Date2021-03 View161
Diffusible Signaling Factor, a Quorum-Sensing Molecule, Interferes with and Is Toxic Towards Bdellovibrio bacteriovorus 109J File

Dwidar, Mohammed , Jang, Hyochan , Sangwan, Naseer , Mun, Wonsik , Im, Hansol , Yoon, Sora , Choi, Sooin , Nam, Dougu , Mitchell, Robert J.

Article Issue Date2021-02 View139
netGO: R-Shiny package for network-integrated pathway enrichment analysis File

Kim, Jinhwan , Yoon, Sora , Nam, Dougu

Article Issue Date2020-05 View123
Benchmarking RNA-seq differential expression analysis methods using spike-in and simulation data File File

Baik, Bukyung , Yoon, Sora , Nam, Dougu

Article Issue Date2020-04 View155
The voltage-gated potassium channel Shaker promotes sleep via thermosensitive GABA transmission File File

Kim, Ji-hyung , Ki, Yoonhee , Lee, Hoyeon , Hur, Moon Seong , Baik, Bukyung , Hur, Jin-Hoe , Nam, Dougu , Lim, Chunghun

Article Issue Date2020-04 View164
Bioinformatics services for analyzing massive genomic datasets File File

Ko, Gunhwan , Kim, Pan-Gyu , Cho, Youngbum , Jeong, Seongmun , Kim, Jae-Yoon , Kim, Kyoung Hyoun , Lee, Ho-Yeon , Han, Jiyeon , Yu, Namhee , Ham, Seokjin , et al

Article Issue Date2020-03 View130
Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer File

Lee, Yu Geon , Nam, Yeji , Shin, Kyeong Jin , Yoon, Sora , Park, Weon Seo , Joung, Jae Young , Seo, Jeong Kon , Jang, Jinho , Lee, Semin , Nam, Dougu , et al

Article Issue Date2020-02 View199
PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273 File File

Khim, Keon Woo , Choi, Sun Sil , Jang, Hyun-Jun , Lee, Yo Han , Lee, Eujin , Hyun, Ji-Min , Eom, Hye-Jin , Yoon, Sora , Choi, Jeong-Won , Park, Tae-Eun , et al

Article Issue Date2020-02 View190
Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCer File

Jang, Hyun-Jun , Lim, Seyoung , Kim, Jung-Min , Yoon, Sora , Lee, Chae Young , Hwang, Hyeon-Jeong , Shim, Jeong Woo , Shin, Kyeong Jin , Kim, Hye Yun , Park, Kwang Il , et al

Article Issue Date2020-01 View204
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 File File

Park, Hye-Kyung , Yoon, Nam Gu , Lee, Ji-Eun , Hu, Sung , Yoon, Sora , Kim, So Yeon , Hong, Jun-Hee , Nam, Dougu , Chae, Young Chan , Park, Jong Bae , et al

Article Issue Date2020-01 View169
Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney Injury File File

Yoo, Eun Jin , Lim, Sun Woo , Kang, Hyun Je , Park, Hyun , Yoon, Sora , Nam, Dougu , Sanada, Satoru , Kwon, Mi Jin , Lee-Kwon, Whaseon , Choi, Soo Youn , et al

Article Issue Date2019-10 View196
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