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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 775 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 771 | - |
dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
dc.citation.volume | 15 | - |
dc.contributor.author | Park, Cheol-Min | - |
dc.contributor.author | Sun, CH | - |
dc.contributor.author | Olejniczak, ET | - |
dc.contributor.author | Wilson, AE | - |
dc.contributor.author | Meadows, RP | - |
dc.contributor.author | Betz, SF | - |
dc.contributor.author | Elmore, SW | - |
dc.contributor.author | Fesik, SW | - |
dc.date.accessioned | 2023-12-22T10:38:25Z | - |
dc.date.available | 2023-12-22T10:38:25Z | - |
dc.date.created | 2014-11-10 | - |
dc.date.issued | 2005-02 | - |
dc.description.abstract | Non-peptidic small molecule SMAC mimetics were designed and synthesized that bind to the BIR3 domain of XIAP using structure-based design. Substituted five-membered heterocycles such as thiazoles and imidazoles were identified that serve as replacements for peptide fragments of the lead. | - |
dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.15, no.3, pp.771 - 775 | - |
dc.identifier.doi | 10.1016/j.bmcl.2004.11.010 | - |
dc.identifier.issn | 0960-894X | - |
dc.identifier.scopusid | 2-s2.0-12444292682 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/8563 | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=12444292682 | - |
dc.identifier.wosid | 000226935700056 | - |
dc.language | 영어 | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.title | Non-peptidic small molecule inhibitors of XIAP | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | SMAC mimetics | - |
dc.subject.keywordAuthor | XIAP inhibitors | - |
dc.subject.keywordPlus | MITOCHONDRIA-DERIVED ACTIVATOR | - |
dc.subject.keywordPlus | APOPTOSIS PROTEIN XIAP | - |
dc.subject.keywordPlus | X-LINKED INHIBITOR |
- |
dc.subject.keywordPlus | STRUCTURAL BASIS | - |
dc.subject.keywordPlus | CELL-DEATH | - |
dc.subject.keywordPlus | BIR DOMAIN | - |
dc.subject.keywordPlus | SMAC/DIABLO | - |
dc.subject.keywordPlus | IAP | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | EXPRESSION | - |
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