BROWSE

Related Researcher

Author's Photo

Park, Cheol-Min
Synthetic & Medicinal Chemistry Lab
Research Interests
  • Organic synthesis, medicinal chemistry, chemical biology

ITEM VIEW & DOWNLOAD

Synthesis of Pyridines by Carbenoid-Mediated Ring Opening of 2H-Azirines

Cited 26 times inthomson ciCited 16 times inthomson ci
Title
Synthesis of Pyridines by Carbenoid-Mediated Ring Opening of 2H-Azirines
Author
Loy, Nicole S. Y.Singh, AlokXu, XianxiuPark, Cheol-Min
Keywords
carbenoids; electrocyclic reactions; heterocycle; ring expansion; synthetic methods
Issue Date
2013-02
Publisher
WILEY-V C H VERLAG GMBH
Citation
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.52, no.8, pp.2212 - 2216
Abstract
Roaming the range: The title reaction tolerates a wide range of substituents on the resulting pyridine ring using mild reaction conditions (see scheme; esp=α,α,α′,α′-tetramethyl-1,3- benzenedipropionic acid). The formation of the key intermediate is catalyst-controlled, and subsequent cyclization and oxidation affords pyridines in excellent yields. The method has been used for the efficient synthesis of polyarylpyridines.
URI
Go to Link
DOI
10.1002/anie.201209301
ISSN
1433-7851
Appears in Collections:
PHY_Journal Papers
Files in This Item:
2-s2.0-84873909860.pdf Download

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU