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Park, Cheol-Min
Synthetic & Medicinal Chemistry Lab
Research Interests
  • Organic synthesis, medicinal chemistry, chemical biology

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Synthesis of 2-aminofurans and 2-unsubstituted furans via carbenoid-mediated [3+2] cycloaddition

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Title
Synthesis of 2-aminofurans and 2-unsubstituted furans via carbenoid-mediated [3+2] cycloaddition
Author
Jiang, YaojiaKhong, Vanessa Zhong YueLourdusamy, EmmanuvelPark, Cheol-Min
Keywords
POLYSUBSTITUTED FURANS; EFFICIENT SYNTHESIS; HETEROCYCLES; DERIVATIVES; PYRROLES; KETONES; ETHERS
Issue Date
2012-03
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.48, no.25, pp.3133 - 3135
Abstract
An efficient dual synthetic manifold for 2-aminofurans and 2-unsubstituted furans has been developed. The carbenoid-mediated [3 + 2] cycloaddition of copper carbenoids with enamines provides 2-amino-2,3-dihydrofurans which serve as common intermediates for both 2-aminofurans and 2-unsubstituted furans.
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DOI
10.1039/c2cc18139h
ISSN
1359-7345
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PHY_Journal Papers
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