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Park, Tae Joo
Developmental Morphogenesis Lab
Research Interests
  • Morphogenesis, chondrogenesis, ciliogenesis

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Cloning and characterization of TMPRSS6, a novel type 2 transmembrane serine protease

Cited 11 times inthomson ciCited 9 times inthomson ci
Title
Cloning and characterization of TMPRSS6, a novel type 2 transmembrane serine protease
Author
Park, Tae JooLee, YJKim, HJPark, HGPark, WJ
Issue Date
2005-04
Publisher
KOREAN SOC MOLECULAR & CELLULAR BIOLOGY
Citation
MOLECULES AND CELLS, v.19, no.2, pp.223 - 227
Abstract
We have identified TMPRSS6, a novel type 2 transmembrane serine protease. TMPRSS6 possesses all the signature motifs of the family of transmembrane serine proteases (TMPRSSs), including a transmembrane domain, an LDL receptor class A (LDLRA) domain, a scavenger receptor cysteine-rich (SRCR) domain, and a serine protease domain. The substrate specificity of TMPRSS6 is slightly different from those of other TMPRSS family members. Combined with the finding that TMPRSS6 is expressed strongly in the thyroid and weakly in the trachea, this may indicate that TMPRSS6 has a specialized role.
URI
https://scholarworks.unist.ac.kr/handle/201301/7190
URL
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=26044435171
ISSN
1016-8478
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BIO_Journal Papers
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