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Kang, Sebyung
Protein Nanobio Lab
Research Interests
  • Protein engineering, Drug/diagnostics delivery nanoplatform, Protein-based vaccine delivery systems, Biosensor & imaging

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Controlled Assembly of Bifunctional Chimeric Protein Cages and Composition Analysis Using Noncovalent Mass Spectrometry

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Title
Controlled Assembly of Bifunctional Chimeric Protein Cages and Composition Analysis Using Noncovalent Mass Spectrometry
Author
Kang, SebyungOltrogge, Luke M.Broomell, Chris C.Liepold, Lars O.Prevelige, Peter E.Young, MarkDouglas, Trevor
Issue Date
2008-12
Publisher
AMER CHEMICAL SOC
Citation
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.130, no.49, pp.16527 - 16529
Abstract
The chimeric protein cages having dual functionalities inside and outside of LiDps are constructed by reassembling dissociated subunits with desired ratios and their compositions are monitored by noncovalent mass spectrometry at the molecular level. Binomial distribution analysis of mass spectra reveals that dissociated subunits reassemble randomly into a dodecameric cage.
URI
https://scholarworks.unist.ac.kr/handle/201301/6450
URL
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=57549103949
DOI
10.1021/ja807655t
ISSN
0002-7863
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BIO_Journal Papers
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