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- Cho, Yoon-Kyoung
- FRUITS Lab.
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Clinical evaluation of size-based circulating tumor cell enumeration lab-on-a-disc
- Author(s)
- Lim, Minji, Kim, Tae-Hyeong, Park, Juhee, Cho, Yoon-Kyoung
- Issued Date
- 2015-10-27
- Citation
- 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015, pp.102 - 104
- Abstract
- Circulating tumor cell (CTC) is a critical component of metastasis. Here, we suggest a lab-on-a-disc for CTC enumeration from whole blood. The disc allows gentle yet efficient size-based filtration, achieving high recovery rate (95%) and log depletion of WBC (2.5). Moreover, applicability of whole blood without dilution and fast processing time (1 min for 3 mL of whole blood) enhances the utility of our system. Due to these advantages, this disc is exceptional in the field of CTC isolation and can be a powerful tool for cancer diagnosis and detecting cancer metastasis.
- Publisher
- Chemical and Biological Microsystems Society
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