BROWSE

Related Researcher

Author's Photo

Kim, Jiyun
School of Materials Science and Engineering
Research Interests

ITEM VIEW & DOWNLOAD

Microspinning: Local Surface Mixing via Rotation of Magnetic Microparticles for Efficient Small-Volume Bioassays

Cited 0 times inthomson ciCited 0 times inthomson ci
Title
Microspinning: Local Surface Mixing via Rotation of Magnetic Microparticles for Efficient Small-Volume Bioassays
Author
Kim, Su DeokSong, Seo WooOh, Dong YoonLee, Amos ChungwonKoo, Jeong WooKang, TaehunKim, Min ChangLee, ChangheeJeong, YunjinJeong, Hyun YongLee, DaewonCho, SeongkyuKwon, SunghoonKim, Jiyun
Issue Date
2020-02
Publisher
MDPI
Citation
MICROMACHINES, v.11, no.2, pp.175
Abstract
The need for high-throughput screening has led to the miniaturization of the reaction volume of the chamber in bioassays. As the reactor gets smaller, surface tension dominates the gravitational or inertial force, and mixing efficiency decreases in small-scale reactions. Because passive mixing by simple diffusion in tens of microliter-scale volumes takes a long time, active mixing is needed. Here, we report an efficient micromixing method using magnetically rotating microparticles with patterned magnetization induced by magnetic nanoparticle chains. Because the microparticles have magnetization patterning due to fabrication with magnetic nanoparticle chains, the microparticles can rotate along the external rotating magnetic field, causing micromixing. We validated the reaction efficiency by comparing this micromixing method with other mixing methods such as simple diffusion and the use of a rocking shaker at various working volumes. This method has the potential to be widely utilized in suspension assay technology as an efficient mixing strategy.
URI
https://scholarworks.unist.ac.kr/handle/201301/31550
URL
https://www.mdpi.com/2072-666X/11/2/175
DOI
10.3390/mi11020175
ISSN
2072-666X
Appears in Collections:
MSE_Journal Papers
Files in This Item:
000520181500064.pdf Download

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU