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Ghim, Cheol-Min
Physical Biology & Biological Physics
Research Interests
  • Control of complex networks, stochastic cell biology, biochemical information processing, human microbiome, ecological inference

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Synthetic Biology for Biofuels: Building Designer Microbes from the Scratch

Cited 18 times inthomson ciCited 16 times inthomson ci
Title
Synthetic Biology for Biofuels: Building Designer Microbes from the Scratch
Author
Ghim, Cheol-MinKim, TaesungMitchell, Robert J.Lee, Sung Kuk
Keywords
Biological parts; Building designers; Isoprenoids; Lignocellulose; Part standardization; Synthetic biology; Transportation fuels
Issue Date
2010-01
Publisher
KOREAN SOC BIOTECHNOLOGY & BIOENGINEERING
Citation
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.15, no.1, pp.11 - 21
Abstract
The ultimate goal in the production of biofuels is to produce fuels identical or similar to petroleum-derived transportation fuels more efficiently and in commercial quantities. Synthetic biologists have been engineering microbes to synthesize biofuels, such as butanol and fatty acid-or isoprenoid-based fuels, which are nearly identical to gasoline and diesel. One of the most urgent demands along this direction is to attain a solid framework for characterizing and standardizing the biological parts and devices. It seems quite promising because biotechnologies specially based on miniaturizations have been making a big contribution to this work. Therefore, in this review, recent advances and difficulties in the biofuel field are discussed, along with the advances of synthetic biology, which will make it possible to create designer microorganisms that produce economically viable next generation biofuels, aside from bioethanol, from corn or sugar cane, and biodiesel from plant or animal oils.
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DOI
10.1007/s12257-009-3065-5
ISSN
1226-8372
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MNE_Journal Papers
SLS_Journal Papers
ECHE_Journal Papers
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