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Kim, Jiyun
School of Materials Science and Engineering
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Independent Control of Topography for 3D Patterning of the ECM Microenvironment

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Title
Independent Control of Topography for 3D Patterning of the ECM Microenvironment
Author
Kim, JiyunStaunton, Jack RoryTanner, Kandice
Keywords
3D biomaterials; biomimetic extracellular matrix; extracellular matrix topography; magnetic-field-directed self-assembly
Issue Date
2016-01
Publisher
WILEY-V C H VERLAG GMBH
Citation
ADVANCED MATERIALS, v.28, no.1, pp.132 -
Abstract
Biomimetic extracellular matrix (ECM) topographies driven by the magnetic-field-directed self-assembly of ECM protein-coated magnetic beads are fabricated. This novel bottom-up method allows us to program isotropic, anisotropic, and diverse hybrid ECM patterns without changing other physicochemical properties of the scaffold material. It is demonstrated that this 3D anisotropic matrix is able to guide the dendritic protrusion of cells.
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DOI
10.1002/adma.201503950
ISSN
0935-9648
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MSE_Journal Papers
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