BROWSE

Related Researcher

Author's Photo

Suh, Pann-Ghill
BioSignal Network Lab (BSN)
Research Interests
  • Signal transduction, cancer, metabolism, phospholipase C

ITEM VIEW & DOWNLOAD

PROMOTER REGION OF THE RAT PHOSPHOLIPASE C-GAMMA-1 GENE

Cited 9 times inthomson ciCited 5 times inthomson ci
Title
PROMOTER REGION OF THE RAT PHOSPHOLIPASE C-GAMMA-1 GENE
Author
Lee, Seung-JaeRyu, Sung HoSuh, Pann-Ghill
Issue Date
1993-07
Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
Citation
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.194, no.1, pp.294 - 300
Abstract
We have cloned the upstream region of the rat phospholipase C-γ1 gene andcharacterized its promoter activity. The 5′-upstream sequence is highly rich in GC, enriched with CpG dinucleotides and lacks a TATA motif. This sequence also contains many putative binding sites for regulatory proteins. Primer extension and RNase protection assay demonstrated a single transcriptional start site located at 103 nucleotides upstream of the ATG start codon. The transcriptional activities of various 5′-deleted fragments, fused with chloramphenicol acetyltransferase gene, were examined after transfection into C2C12 myoblast. Multiple positive and negative regulatory sites were observed. © 1993 Academic Press. All rights reserved.
URI
https://scholarworks.unist.ac.kr/handle/201301/16459
URL
http://www.sciencedirect.com/science/article/pii/S0006291X83718188
DOI
10.1006/bbrc.1993.1818
ISSN
0006-291X
Appears in Collections:
BIO_Journal Papers
Files in This Item:
There are no files associated with this item.

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU