dc.citation.endPage |
300 |
- |
dc.citation.number |
1 |
- |
dc.citation.startPage |
294 |
- |
dc.citation.title |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
- |
dc.citation.volume |
194 |
- |
dc.contributor.author |
Lee, Seung-Jae |
- |
dc.contributor.author |
Ryu, Sung Ho |
- |
dc.contributor.author |
Suh, Pann-Ghill |
- |
dc.date.accessioned |
2023-12-22T13:06:26Z |
- |
dc.date.available |
2023-12-22T13:06:26Z |
- |
dc.date.created |
2015-08-20 |
- |
dc.date.issued |
1993-07 |
- |
dc.description.abstract |
We have cloned the upstream region of the rat phospholipase C-γ1 gene andcharacterized its promoter activity. The 5′-upstream sequence is highly rich in GC, enriched with CpG dinucleotides and lacks a TATA motif. This sequence also contains many putative binding sites for regulatory proteins. Primer extension and RNase protection assay demonstrated a single transcriptional start site located at 103 nucleotides upstream of the ATG start codon. The transcriptional activities of various 5′-deleted fragments, fused with chloramphenicol acetyltransferase gene, were examined after transfection into C2C12 myoblast. Multiple positive and negative regulatory sites were observed. © 1993 Academic Press. All rights reserved. |
- |
dc.identifier.bibliographicCitation |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.194, no.1, pp.294 - 300 |
- |
dc.identifier.doi |
10.1006/bbrc.1993.1818 |
- |
dc.identifier.issn |
0006-291X |
- |
dc.identifier.scopusid |
2-s2.0-0027213569 |
- |
dc.identifier.uri |
https://scholarworks.unist.ac.kr/handle/201301/16459 |
- |
dc.identifier.url |
http://www.sciencedirect.com/science/article/pii/S0006291X83718188 |
- |
dc.identifier.wosid |
A1993LM60300043 |
- |
dc.language |
영어 |
- |
dc.publisher |
ACADEMIC PRESS INC ELSEVIER SCIENCE |
- |
dc.title |
PROMOTER REGION OF THE RAT PHOSPHOLIPASE C-GAMMA-1 GENE |
- |
dc.type |
Article |
- |
dc.description.journalRegisteredClass |
scopus |
- |