BROWSE

Related Researcher

Author's Photo

Bhak, Jong
KOrean GenomIcs Center(KOGIC)
Research Interests
  • Geromics, genomics, bioinformatics, protein Engineering, OMICS

ITEM VIEW & DOWNLOAD

Pocket extraction on proteins via the Voronoi diagram of spheres

Cited 19 times inthomson ciCited 21 times inthomson ci
Title
Pocket extraction on proteins via the Voronoi diagram of spheres
Other Titles
Pocket extraction on proteins via the Voronoi diagram of spheres.
Author
Kim, DongukCho, Cheol-HyungCho, YoungsongRyu, JoonghyunBhak, Jong HwaKim, Deok-Soo
Keywords
Voronoi diagram of atoms; protein; pocket; binding site; docking; protein surface; blending mesh
Issue Date
2008-04
Publisher
ELSEVIER SCIENCE INC
Citation
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, v.26, no.7, pp.1104 - 1112
Abstract
Proteins consist of atoms. Given a protein, the automatic recognition of depressed regions, called pockets, on the surface of proteins is important for protein-ligand docking and facilitates fast development of new drugs. Recently, computational approaches have emerged for recognizing pockets from the geometrical point of view. Presented in this paper is a geometric method for the pocket recognition which is based on the Voronoi diagram for atoms. Given a Voronoi diagram, the proposed algorithm transforms the atomic structure to meshes which contain the information of the proximity among atoms, and then recognizes depressions on the surface of a protein using the meshes. (c) 2007 Elsevier Inc. All rights reserved
URI
Go to Link
DOI
10.1016/j.jmgm.2007.10.002
ISSN
1093-3263
Appears in Collections:
BME_Journal Papers
Files in This Item:
1-s2.0-S1093326307001507-main.pdf Download

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU