김홍태
Kim, Hongtae

김홍태

Department of Biological Sciences(생명과학과)

Research Interests
Cancer;DNA damage response;DDR;CML;Chronic myelogenous leukemia;암;DNA 복구;DNA 손상 반응;만성골수성백혈병;백혈병
Lab Description
My lab focuses on studying the DNA damage response pathway and development/progression of chronic myeloid leukemia (CML). DNA damage responses are important in maintaining genetic stability in eukaryotic cells. Because many tumor suppressor proteins including ATM, ATR, MDC1, RNF8, RNF168, RAP80, BRCA1, and BRCA2 are involved in the DNA damage pathway, the complete understanding of this pathway is important in preventing neoplastic transformation. So, our laboratory’s goal is to understand the inherent genetic stability and molecular mechanisms of tumorigenesis by studying DNA damage signaling pathways. CML study is the second project in my Lab. My Lab has focused on identifying genes that are resistant to the tyrosine kinase inhibitor of CML. In addition, we are studying the molecular mechanisms of the discovered genes and applying them to CML patients. The aim of this research project is to ultimately contribute to the treatment and diagnosis of chronic myelogenous leukemia.

Oh, Jung-MinKang, YujinPark, JumiSung, YubinKim, DayoungSeo, YuriLee, EunARa, JaeSunAmarsanaa, EnkhzulPark, Young-Un , et al

Article Issue Date2023-06 View24

Lee, Shin-AiLee, DayeKang, MinhwaKim, SoraKwon, Su-JungLee, Han-SaeSeo, Hye-RanKaushal, PrashantLee, Nam SooKim, Hongtae , et al

Article Issue Date2022-12 View22

Kim, SoomiPark, KibeomOh, Jung-MinKim, Hongtae

Article Issue Date2021-12 View20

Kang, Hyun JeEom, Hye-jinKim, HongtaeMyung, KyungjaeKwon, Hyug MooChoi, Jang Hyun

Article Issue Date2021-10 View31

Han, Ye GiYun, MiyongChoi, MinjiLee, Seok-GeunKim, Hongtae

Article Issue Date2019-06 View21

Kim, DoyeunKim, SunmiOh, YoungsunPark, SonghwaJeon, YoonKim, HongtaeLee, HoKim, Sunghoon

Article Issue Date2018-10 View18
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