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박지영
Park, Jiyoung

박지영

생명과학과

  • Molecular Metabolism Lab.
  • Website
Research Interests
Obesity;cancer-associated adipocyte;dermal adipocyte;diabetes;cancer;adipose tissue;Adipocyte;당뇨;암
Lab Description
Our research group is mainly focusing on the adipocyte biology at the level of metabolism and cancer.
Through underlying the molecular mechanisms of obesity-related metabolic diseases, we aim to develop novel therapeutics for the metabolism and cancers. Main research topics are listed in below;1. Adipose tissue remodeling via modulation of extracellular matrix proteins2. Development of adipokine-based therapeutics for obesity-related metabolic diseases3. Underlying the signaling networks between stromal adipocytes and cancer cells within the tumor microenvironment4. Underlying the molecular mechanisms of metabolic stress-induced alteration of cancer cell behaviors
Researcher ID Research Gate ORCiD Scopus Google Scholar
Previous
Targeting COL6A3-C5 with nigericin suppresses endotrophin formation and enhances insulin sensitivity in obesity File File

Kim, Chu-Sook , Jo, Woobeen , Yoo, Jungsun , Kim, Min , An, Jin-Pyo , Oh, Won-Keun , Park, Jiyoung

Article Issue Date2026-03 View3
Nigericin targets COL6A3-C5 domain to inhibit MMP-mediated endotrophin cleavage, enhancing insulin sensitivity in obesity

Kim, Chu-Sook , Jo, Woobeen , Yoo, Jungsun , Kim, Min , An, Jin-Pyo , Oh, Won-Keun , Park, Jiyoung

Article Issue Date2025-12 View68
Ginkgo biloba extract ameliorates skin fibrosis in a bleomycin-induced mouse model of systemic sclerosis File

Lee, Beomgu , Roh, Jong Seong , Jeong, Hoim , Kim, Yerin , Lee, Jihyeon , Yun, Changun , Park, Jiyoung , Kim, Da-sol , Lee, Jungsoo , So, Min Wook , et al

Article Issue Date2024-12 View189
FAM3C in cancer-associated adipocytes promotes breast cancer cell survival and metastasis File

Kim, Sahee , Oh, Jiyoung , Park, Chanho , Kim, Min , Jo, Woobeen , Kim, Chu-Sook , Cho, Sun Wook , Park, Jiyoung

Article Issue Date2024-02 View157
Ubiquitin ligase RNF20 coordinates sequential adipose thermogenesis with brown and beige fat-specific substrates File File

Jeon, Yong Geun , Nahmgoong, Hahn , Oh, Jiyoung , Lee, Dabin , Kim, Dong Wook , Kim, Jane Eunsoo , Kim, Ye Young , Ji, Yul , Han, Ji Seul , Kim, Sung Min , et al

Article Issue Date2024-01 View150
Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice File File

Han, Sang Mun , Park, Eun Seo , Park, Jeu , Nahmgoong, Hahn , Choi, Yoon Ha , Oh, Jiyoung , Yim, Kyung Min , Lee, Won Taek , Lee, Yun Kyung , Jeon, Yong Geun , et al

Article Issue Date2023-12 View144
High levels of intracellular endotrophin in adipocytes mediate COPII vesicle supplies to autophagosome to impair autophagic flux and contribute to systemic insulin resistance in obesity File

Oh, Jiyoung , Park, Chanho , Kim, Sahee , Kim, Min , Kim, Chu-Sook , Jo, Woobeen , Park, Sung Ho , Yi, Gwan-Su , Park, Jiyoung

Article Issue Date2023-08 View150
DSCR1 deficiency ameliorates the Aβ pathology of Alzheimer's disease by enhancing microglial activity File File

Choi, Chiyeol , Kim, Hyerin , Oh, Jiyoung , Park, Chanho , Kim, Min , Kim, Chu-Sook , Park, Jiyoung

Article Issue Date2023-02 View211
Epigenetic regulation of Neuregulin 1 promotes breast cancer progression associated to hyperglycemia File File

Lee, Changhu , Kim, Min , Park, Chanho , Jo, Woobeen , Seo, Jeong Kon , Kim, Sahee , Oh, Jiyoung , Kim, Chu-Sook , Ryu, Han Suk , Lee, Kyung-Hun , et al

Article Issue Date2023-01 View182
Extracellular matrix remodeling facilitates obesity-associated cancer progression File

Kim, Min , Lee, Changhu , Park, Jiyoung

Article Issue Date2022-10 View144
Adipocyte mesenchymal transition contributes to mammary tumor progression File File

Zhu, Qingzhang , Zhu, Yi , Hepler, Chelsea , Zhang, Qianbin , Park, Jiyoung , Gliniak, Christy , Henry, Gervaise H. , Crewe, Clair , Bu, Dawei , Zhang, Zhuzhen , et al

Article Issue Date2022-09 View221
MicroRNA-29 Ameliorates Fibro-Inflammation and Insulin Resistance in HIF1α-Deficient Obese Adipose Tissue by Inhibiting Endotrophin Generation File

Jo, Woobeen , Kim, Min , Oh, Jiyoung , Kim, Chu-Sook , Park, Chanho , Yoon, Sora , Lee, Changhu , Kim, Sahee , Nam, Dougu , Park, Jiyoung

Article Issue Date2022-08 View190
Targeted erasure of DNA methylation by TET3 drives adipogenic reprogramming and differentiation File

Park, Jeu , Lee, Do Hoon , Ham, Seokjin , Oh, Jiyoung , Noh, Jung-Ran , Lee, Yun Kyung , Park, Yoon Jeong , Lee, Gung , Han, Sang Mun , Han, Ji Seul , et al

Article Issue Date2022-07 View177
Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA File

Lee, Yo Han , Jang, Hyun-Jun , Kim, Sounkou , Choi, Sun Sil , Khim, Keon Woo , Eom, Hye-Jin , Hyun, Jimin , Shin, Kyeong Jin , Chae, Young Chan , Kim, Hongtae , et al

Article Issue Date2021-12 View202
DSCR1 upregulation enhances dural meningeal lymphatic drainage to attenuate amyloid pathology of Alzheimer's disease File

Choi, Chiyeol , Park, Jiwon , Kim, Hyerin , Chang, Karen T , Park, Jiyoung , Min, Kyung-Tai

Article Issue Date2021-11 View115
Vernicia fordii (Hemsl.) Airy Shaw extract stimulates insulin secretion in pancreatic beta-cells and improves insulin sensitivity in diabetic mice File

Hyun, Jimin , Park, Mi Hyeon , Lee, Yo Han , Lee, Youngeun , Jeong, Su Ji , Choi, Sun Sil , Khim, Keon Woo , Eom, Hye Jin , Hur, Jin-Hoe , Park, Chan Young , et al

Article Issue Date2021-10 View186
Type VI collagen and its cleavage product, endotrophin, cooperatively regulate the adipogenic and lipolytic capacity of adipocytes File

Oh, Jiyoung , Kim, Chu-Sook , Kim, Min , Jo, Woobeen , Sung, Young Hoon , Park, Jiyoung

Article Issue Date2021-01 View147
Verminoside from Pseudolysimachion rotundum var. subintegrum sensitizes cisplatin-resistant cancer cells and suppresses metastatic growth of human breast cancer File File

Lee, Changhu , Ryu, Hyung Won , Kim, Sahee , Kim, Min , Oh, Sei-Ryang , Ahn, Kyung-Seop , Park, Jiyoung

Article Issue Date2020-11 View134
The impact of endotrophin on the progression of chronic liver disease File File

Kim, Min , Lee, Changhu , Seo, Dae Yun , Lee, Hyojung , Horton, Jay D. , Park, Jiyoung , Scherer, Philipp E.

Article Issue Date2020-10 View114
Broussonetia papyrifera Root Bark Extract Exhibits Anti-inflammatory Effects on Adipose Tissue and Improves Insulin Sensitivity Potentially Via AMPK Activation File File

Lee, Jae Min , Choi, Sun Sil , Park, Mi Hyeon , Jang, Hyunduk , Lee, Yo Han , Khim, Keon Woo , Oh, Sei Ryang , Park, Jiyoung , Ryu, Hyung Won , Choi, Jang Hyun

Article Issue Date2020-03 View151
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