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박찬영
Park, Chan Young

박찬영

Department of Biomedical Engineering(바이오메디컬공학과)

Research Interests
Medical Science;autoimmune diseases;immune system activation;calcium signaling;translational medicine
Lab Description
The goal of our research is to understand how calcium signaling is important and diverse. Numerous vital physiological processes such as cell division, proliferation, apoptosis, gene transcription, and immune cell activation are regulated by calcium channels. Consequently, calcium channels are important for many pathological processes and diseases including autism, immune deficiency syndrome, and cardiovascular diseases. We are interested in the dynamic calcium signaling events mediated by voltage-gated calcium channels (VGCCs) and store-operated calcium channels (SOCs).Another goal is to provide effective solutions designed to boost your ability, to ensure you achieve your dreams of success, and to help you be a nice lab citizen.​
Researcher ID Research Gate ORCiD Scopus Google Scholar
Previous
Phosphorylation of EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha) is indispensable for nuclear translocation of TFEB and TFE3 during ER stress File

Dang, Thao Thi , Kim, Mi-Jeong , Lee, Yoon Young , Le, Hien Thi , Kim, Kook Hwan , Nam, Somi , Hyun, Seung Hwa , Kim, Hong Lim , Chung, Su Wol , Chung, Hun Taeg , et al

Article Issue Date2023-07 View36
Macrophage transcription factor TonEBP promotes systemic lupus erythematosus and kidney injury via damage-induced signaling pathways File File

Yoo, Eun Jin , Oh, Kook-Hwan , Piao, Honglin , Kang, Hyun Je , Jeong, Gyu Won , Park, Hyun , Lee, Chang Jun , Ryu, Hyunjin , Yang, Seung Hee , Kim, Myung-Gyu , et al

Article Issue Date2023-07 View46
Orai1 is an entotic Ca2+ channel for non-apoptotic cell death, entosis in cancer development File File

Lee, Ah Reum , Park, Chan Young

Article Issue Date2023-05 View30
Human coronavirus 3CL proteases cleave septins and disrupt Hedgehog signaling, causing ciliary dysfunction File

Lee, Ah Reum , Kweon, Yeong Cheon , Lee, Sang Min , Park, Chan Young

Article Issue Date2023-03 View24
GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base File File

Jang, Dong Gil , Kwon, Keun Yeong , Kweon, Yeong Cheon , Kim, Byung-gyu , Myung, Kyungjae , Lee, Hyun-Shik , Park, Chan Young , Kwon, Taejoon , Park, Tae Joo

Article Issue Date2022-08 View33
Metastasis enhancer PGRMC1 boosts store-operated Ca2+ entry by uncoiling Ca2+ sensor STIM1 for focal adhesion turnover and actomyosin formation File File

Lee, Sang Kwon , Kweon, Yeong Cheon , Lee, Ah Reum , Lee, Yoon Young , Park, Chan Young

Article Issue Date2022-01 View24
Vernicia fordii (Hemsl.) Airy Shaw extract stimulates insulin secretion in pancreatic beta-cells and improves insulin sensitivity in diabetic mice File

Hyun, Jimin , Park, Mi Hyeon , Lee, Yo Han , Lee, Youngeun , Jeong, Su Ji , Choi, Sun Sil , Khim, Keon Woo , Eom, Hye Jin , Hur, Jin-Hoe , Park, Chan Young , et al

Article Issue Date2021-10 View39
Simultaneous Real-Time Three-Dimensional Localization and FRET Measurement of Two Distinct Particles File

Chen, Xingxiang , Liu, Teng , Qin, Xianan , Quang Quan Nguyen , Lee, Sang Kwon , Lee, Chanwoo , Ren, Yaguang , Chu, Jun , Zhu, Guang , Yoon, Tae-Young , et al

Article Issue Date2021-09 View33
Accessibility-dependent topology studies of membrane proteins using a SpyTag/SpyCatcher protein-ligation system File

Bae, Yoonji , Lee, Sang Kwon , Chae, Young Chan , Park, Chan Young , Kang, Sebyung

Article Issue Date2021-04 View35
Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis File File

Choi, Sun Sil , Lee, Sang Kwon , Kim, Joong Kwan , Park, Hye-Kyung , Lee, Eujin , Jang, Jinho , Lee, Yo Han , Khim, Keon Woo , Hyun, Ji-Min , Eom, Hye-jin , et al

Article Issue Date2020-06 View44
Increased Confinement and Polydispersity of STIM1 and Orai1 after Ca2+ Store Depletion File

Qin, Xianan , Liu, Lei , Lee, Sang Kwon , Alsina, Adolfo , Liu, Teng , Wu, Chao , Park, Hojeong , Yu, Chenglong , Kim, Hajin , Chu, Jun , et al

Article Issue Date2020-01 View30
The inactivation domain of STIM1 acts through intramolecular binding to the coiled-coil domain in the resting state File

Lee, Sang Kwon , Lee, Min-hsun , Jeong, Su Ji , Qin, Xianan , Lee, Ah Reum , Park, Hyokeun , Park, Chan Young

Article Issue Date2020-01 View19
Orai1 inhibitor STIM2β regulates myogenesis by controlling SOCE dependent transcriptional factors File File

Kim, Kyu Min , Rana, Anshul , Park, Chan Young

Article Issue Date2019-07 View26
ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis. File

Song, Eun Kyung , Jeon, Jimin , Jang, Dong Gil , Kim, Ha Eun , Sim, Hyo Jung , Kwon, Keun Yeong , Medina-Ruiz, Sofia , Jang, Hyun-Jun , Lee, Ah Reum , Rho, Jun Gi , et al

Article Issue Date2018-10 View25
Distinct gating mechanism of SOC channel involving STIM-Orai coupling and an intramolecular interaction of Orai in Caenorhabditis elegans File

Kim, Kyu Min , Wijerathne, Tharaka , Hur, Jin-Hoe , Kang, Uk Jung , Kim, Ihn Hyeong , Kweon, Yeong Cheon , Lee, Ah Reum , Jeong, Su Ji , Lee, Sang Kwon , Lee, Yoon Young , et al

Article Issue Date2018-05 View18
Molecular interactions of autophagy with the immune system and cancer File File

Jin, Yunho , Hong, Yunkyung , Park, Chan Young , Hong, Yonggeun

Article Issue Date2017-08 View24
A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies File

Zhang, Yongliang , Fox, Jennifer T. , Park, Young-Un , Elliott, Gene , Rai, Ganesha , Cai, Mengli , Sakamuru, Srilatha , Huang, Ruili , Xia, Menghang , Lee, Kyeryoung , et al

Article Issue Date2016-07 View33
Establishment of feeder-free culture system for human induced pluripotent stem cell on DAS nanocrystalline graphene File File

Lee, Hyunah , Nam, Donggyu , Choi, Jae Kyung , Araúzo‐Bravo, Marcos J , Kwon, Soon-Yong , Zaehres, Holm , Lee, Taehee , Park, Chan Young , Kang, Hyun Wook , Hans Robert Shoeler , et al

Article Issue Date2016-02 View31
Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channels File

Rana, Anshul , Yen, Michelle , Sadaghiani, Amir Masoud , Malmersjo, Seth , Park, Chan Young , Dolmetsch, Ricardo E. , Lewis, Richard S.

Article Issue Date2015-06 View22
Identification of Orai1 channel inhibitors by using minimal functional domains to screen small molecule microarrays File

Sadaghiani, Amir Masoud Sadaghiani , Lee, Sang Min , Odegaard, Justin I. , Leveson-Gower, Dennis B. , McPherson, Olivia M. , Novick, Paul , Kim, Mi Ri , Koehler, Angela N. , Negrin, Robert , Dolmetsch, Ricardo E. , et al

Article Issue Date2014-10 View29
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