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Chae, Young Chan

채영찬

생명과학과

Cancer Translational Research Lab.
Website

Research Interests: Cancer Metabolism;Stress Response of Cancer;Mitochondria of Cancer;Tumor Microenvironment

Lab Description: Research interest in Cancer Metabolism, Stress Response of Cancer, Mitochondria of Cancer, Molecular Mechanisms of Cancer Initiation, Progression and Therapy, Mechanism of tumor therapeutic resistance.

Researcher ID Research Gate ORCiD Scopus Google Scholar

Metabolic crosstalk among cancer-associated fibroblasts, adipocytes and immune cells as an immunosuppressive tumor microenvironment driver File File

Kim, Tae Hyun , Lim, Seong Hun , Lee, Hyesung , Chae, Young Chan , Min, Do Sik

Article Issue Date2026-03 View14

Metabolic crosstalk among cancer-associated fibroblasts, adipocytes, and immune cells as an immunosuppressive tumor microenvironment driver File File

Kim, Tae Hyun , Lim, Seong Hun , Lee, Hyesung , Chae, Young Chan , Min, Do Sik

Article Issue Date2026-02 View39

NSMF modulates replication stress to facilitate colorectal cancer progression File File

Shin, Kyeong Jin , Lee, Yu Jin , Kim, Gyuri , You, Seongjun , Kim, Kyoung Lock , Park, Sabin , Lee, KyoungJun , Lee, Eun A , Park, Do Hong , Kim, Hui Won , et al

Article Issue Date2026-01 View38

Regulation of cargo selection in exosome biogenesis and its biomedical applications in cancer File File

Lee, Yu Jin , Shin, Kyeong Jin , Chae, Young Chan

Article Issue Date2024-04 View210

Protocol for evaluation of tumor-derived exosome-induced cancer cell metastasis in a mouse model File File

Lee, Yu Jin , Shin, Kyeong Jin , Chae, Young Chan

Article Issue Date2023-09 View139

Patulin alleviates hepatic lipid accumulation by regulating lipogenesis and mitochondrial respiration File File

Yu, Seungmin , Song, Ji-Hye , Kim, Hee Soo , Hong, Seulmin , Park, Seon Kyeong , Park, Soo Hyun , Lee, Jangho , Chae, Young Chan , Park, Jae Ho , Lee, Yu Geon

Article Issue Date2023-08 View142

Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase File File

Kang, Yujin , Han, Ye Gi , Khim, Keon Woo , Choi, Woo Gyun , Ju, Min Kyung , Park, Kibeom , Shin, Kyeong Jin , Chae, Young Chan , Choi, Jang Hyun , Kim, Hongtae , et al

Article Issue Date2023-08 View324

Diversity and complexity of cell death: a historical review File File

Park, Wonyoung , Wei, Shibo , Kim, Bo-Sung , Kim, Bosung , Bae, Sung-Jin , Chae, Young Chan , Ryu, Dongryeol , Ha, Ki-Tae

Article Issue Date2023-08 View215

GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis File

Lee, Yu Jin , Shin, Kyeong Jin , Jang, Hyun-Jun , Ryu, Jin-Sun , Lee, Chae Young , Yoon, Jong Hyuk , Seo, Jeong Kon , Park, Sabin , Lee, Semin , Je, A Reum , et al

Article Issue Date2023-02 View174

TRAIL & EGFR affibody dual-display on a protein nanoparticle synergistically suppresses tumor growth File

Jun, Heejin , Jang, Eunjung , Kim, Hansol , Yeo, Mirae , Park, Seong Guk , Lee, Jaehyeok , Shin, Kyeong Jin , Chae, Young Chan , Kang, Sebyung , Kim, Eunhee

Article Issue Date2022-09 View235

Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-Kappa B survival machinery in cancer cells File

Min, Seongchun , Kim, Ji Yeon , Cho, Hyo Min , Park, Sujin , Hwang, Ji Min , You, Hyejin , Chae, Young Chan , Lee, Won-Jae , Sun, Woong , Kang, Dongmin , et al

Article Issue Date2022-05 View148

Role of Mitochondrial Stress Response in Cancer Progression File File

Lee, Yu Geon , Park, Do Hong , Chae, Young Chan

Article Issue Date2022-03 View124

Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA File

Lee, Yo Han , Jang, Hyun-Jun , Kim, Sounkou , Choi, Sun Sil , Khim, Keon Woo , Eom, Hye-Jin , Hyun, Jimin , Shin, Kyeong Jin , Chae, Young Chan , Kim, Hongtae , et al

Article Issue Date2021-12 View210

Phospholipase C gamma 1 represses colorectal cancer growth by inhibiting the Wnt/beta-catenin signaling axis File

Shin, Kyeong Jin , Jang, Hyun-Jun , Lee, Yu Jin , Lee, Yu Geon , Suh, Pann-Ghill , Yang, Yong Ryoul , Chae, Young Chan

Article Issue Date2021-09 View136

NSMF promotes the replication stress-induced DNA damage response for genome maintenance File

Ju, Min Kyung , Shin, Kyeong Jin , Lee, Joo Rak , Khim, Keon Woo , Lee, Eun A , Ra, Jae Sun , Kim, Byung-Gyu , Jo, Han-seul , Yoon, Jong Hyuk , Kim, Tae Moon , et al

Article Issue Date2021-06 View154

Accessibility-dependent topology studies of membrane proteins using a SpyTag/SpyCatcher protein-ligation system File

Bae, Yoonji , Lee, Sang Kwon , Chae, Young Chan , Park, Chan Young , Kang, Sebyung

Article Issue Date2021-04 View185

LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival File File

Lee, Yu Geon , Kim, Hui Won , Nam, Yeji , Shin, Kyeong Jin , Lee, Yu Jin , Park, Do Hong , Rhee, Hyun-Woo , Seo, Jeong Kon , Chae, Young Chan

Article Issue Date2021-02 View146

GDC-0980 (apitolisib) treatment with gemcitabine and/or cisplatin synergistically reduces cholangiocarcinoma cell growth by suppressing the PI3K/Akt/mTOR pathway File

Jang, Dong Kee , Lee, Yu Geon , Chae, Young Chan , Lee, Jun Kyu , Paik, Woo Hyun , Lee, Sang Hyub , Kim, Yong-Tae , Ryu, Ji Kon

Article Issue Date2020-09 View111

Selective and Effective Cancer Treatments using Target‐Switchable Intracellular Bacterial Toxin Delivery Systems File

Park, Seong Guk , Choi, Bongseo , Bae, Yoonji , Lee, Yu Geon , Park, Soo Ah , Chae, Young Chan , Kang, Sebyung

Article Issue Date2020-09 View152

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis File File

Choi, Sun Sil , Lee, Sang Kwon , Kim, Joong Kwan , Park, Hye-Kyung , Lee, Eujin , Jang, Jinho , Lee, Yo Han , Khim, Keon Woo , Hyun, Ji-Min , Eom, Hye-jin , et al

Article Issue Date2020-06 View212

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