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Ko, Myunggon (고명곤)

Department
Department of Biological Sciences(생명과학과)
Website
https://myunggonko.wixsite.com/mgko
Lab
Cancer Epigenetics Lab. (종양후생유전학 연구실)
Research Keywords
Leukemia, hematopoiesis, obesity, diabetes, metabolic disease, cancer therapy, cancer
Research Interests
How do alterations in epigenetic landscape disturb the barrier between normal and malignant states to cause cancers? How can we translate these cancer-related aberrations into more efficient cancer therapy? These are two overarching questions that our research is currently addressing. The intricate interplay between genetic and epigenetic pathways plays key roles in regulating normal and malignant cellular development.
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2020-12Direct and rapid detection of 5-hydroxymethylcytosine, a novel cancerhallmark in DNA, using electrochemical reactionLee, Seo Yeon; Qi, Xu; Ko, Myunggon, et alARTICLE67 Direct and rapid detection of 5-hydroxymethylcytosine, a novel cancerhallmark in DNA, using electrochemical reaction
2020-06Decoding ribosomes to keep growing (in AML)An, Jungeun; Ko, MyunggonARTICLE69 Decoding ribosomes to keep growing (in AML)
2020-03Decreased vitamin C uptake mediated by SLC2A3 promotes leukaemia progression and impedes TET2 restorationLiu, Jun; Hong, Junshik; Han, Heejoo, et alARTICLE104 Decreased vitamin C uptake mediated by SLC2A3 promotes leukaemia progression and impedes TET2 restoration
2017-04TET family dioxygenases and DNA demethylation in stem cells and cancersAn, Jungeun; Rao, Anjana; Ko, MyunggonARTICLE494 TET family dioxygenases and DNA demethylation in stem cells and cancers
2016-12DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA MethyltransferasesNair, Varun Sasidharan; Song, Mi Hye; Ko, Myunggon, et alARTICLE561 DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA Methyltransferases
2016-09DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cellsZhang, Xiaotian; Su, Jianzhong; Jeong, Mira, et alARTICLE682 DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells
2016-05TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic ActivitiesMontagner, Sara; Leoni, Cristina; Emming, Stefan, et alARTICLE576 TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities
2015-12DNA methylation and hydroxymethylation in hematologic differentiation and transformationKo, Myunggon; An, Jungeun; Rao, AnjanaARTICLE1074 DNA methylation and hydroxymethylation in hematologic differentiation and transformation
2015-11Acute loss of TET function results in aggressive myeloid cancer in miceAn, Jungeun; Gonzalez-Avalos, E.; Chawla, Ashu, et alARTICLE767 Acute loss of TET function results in aggressive myeloid cancer in mice
2015-11Functions of TET Proteins in Hematopoietic TransformationHan, Jae-A; An, Jungeun; Ko, MyunggonARTICLE728 Functions of TET Proteins in Hematopoietic Transformation
2015-03A zebrafish model of myelodysplasia produced through tet2 genomic editingGjini, Evisa; Mansour, Marc R; Sander, Jeffry D, et alARTICLE1041 A zebrafish model of myelodysplasia produced through tet2 genomic editing
2015-01TET proteins and 5-methylcytosine oxidation in hematological cancersKo, Myunggon; An, Jungeun; Pastor, William A., et alARTICLE806 TET proteins and 5-methylcytosine oxidation in hematological cancers
2014-01Large conserved domains of low DNA methylation maintained by 5-hydroxymethycytosine and Dnmt3aJeong, Mira; Sun, Deqiang; Luo, Min, et alARTICLE681 Large conserved domains of low DNA methylation maintained by 5-hydroxymethycytosine and Dnmt3a
2013-05Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAXKo, Myunggon; An, Jungeun; Bandukwala, Hozefa S, et alARTICLE621 Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
2012-09D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane functionSasaki, Masato; Knobbe, Christiane B; Itsumi, Momoe, et alARTICLE688 D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function
2012-04The SWI/SNF-like BAF complex is essential for early B cell developmentChoi, Jinwook; Ko, Myunggon; Jeon, Shin, et alARTICLE703 The SWI/SNF-like BAF complex is essential for early B cell development
2011-10TET2: epigenetic safeguard for HSCKo, Myunggon; Rao, AnjanaARTICLE552 TET2: epigenetic safeguard for HSC
2011-08Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in miceKo, Myung Gon; Bandukwala, Hozefa S; An, Jungeun, et alARTICLE634 Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
2011-05Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cellsPastor, William A; Pape, Utz J; Huang, Yun, et alARTICLE779 Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
2011-01Srg3 is a novel p53 target and acts as a tumor suppressor by modulating p21WAF1/CIP1 expressionAhn, Jungeun; Ko, Myung Gon; Lee, Changjin, et alARTICLE724 Srg3 is a novel p53 target and acts as a tumor suppressor by modulating p21WAF1/CIP1 expression

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