BROWSE

Related Researcher

Author's Photo

Bhak, Jong
KOrean GenomIcs Center(KOGIC)
Research Interests
  • Geromics, genomics, bioinformatics, protein Engineering, OMICS

ITEM VIEW & DOWNLOAD

Sphericity of a protein via the beta-complex

Cited 7 times inthomson ciCited 7 times inthomson ci
Title
Sphericity of a protein via the beta-complex
Author
Kim, Deok-SooKim, Jae-KwanWon, Chung-InKim, Chong-MinPark, Joon YoungBhak, Jong Hwa
Keywords
β-complex; β-shape; PDB; Protein structure; Sphericity; Voronoi diagram
Issue Date
2010-04
Publisher
ELSEVIER SCIENCE INC
Citation
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, v.28, no.7, pp.636 - 649
Abstract
Molecular shape is a fundamental factor in determining the function of a molecule. As proteins tend to fold into globular shapes, the shape descriptor for protein sphericity is important in understanding molecular functions. In this paper, a definition of protein sphericity is introduced based on the recently developed geometric constructs of the β-complex and β-shape of a protein. The β-complex represents the Euclidean proximity among all the atoms in a protein, and the β-shape is the polyhedron contained within the boundary of the corresponding β-complex. Hence, the β-shape determines the proximity among the atoms on the boundary of a protein. Given the volume of a β-shape, the ratio between the surface area of a sphere with this volume and the surface area of the β-shape itself is a good measure to classify the sphericity of a protein, especially when the radius of a probe is 3.0 A. The presented measure is invariant to translation and rotation.
URI
Go to Link
DOI
10.1016/j.jmgm.2010.01.001
ISSN
1093-3263
Appears in Collections:
BME_Journal Papers
Files in This Item:
2-s2.0-76549089189.pdf Download

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU