Transport phenomena are essential to both natural and engineered systems, and micro-/nanofluidics has emerged as a powerful platform for investigating these effects. At the nanoscale, ion transport is influenced by surface charges, electric double layers (EDLs), and other structural features. To fully capture such complexity, this study takes experimental approaches to examine how multiphysical fields interact with nanostructures. Using tunable nanopore-based systems fabricated through evaporation and pervaporation, we explore how physicochemical fields, combined with modulations of pore size, surface charge, influence ion transport. The results reveal interdependencies between physicochemical conditions and structural properties, offering new insights into the regulation of nanoscopic ion transport.