Obstructive sleep apnea (OSA) is common among older populations and in dividuals with cardiovascular diseases. OSA diagnosis is primarily conducted using polysomnography or recommended home sleep apnea test (HSAT) devices. Wireless wear able devices have emerged as promising tools for OSA screening and follow-up. This study introduces a novel automated algorithm for detecting OSA using abdominal movement signals and acceleration data collected by a wireless abdomen-worn sensor (Soomirang). Thirty-seven subjects underwent overnight monitoring using an HSAT device and the Soomirang system simultaneously. Normal and apnea events were classified using an MLP-MixerdeeplearningmodelbasedonSoomirangdata, whichwasalsousedtoestimate total sleep time (ST). Pearson correlation and Bland–Altman analyses were conducted to evaluate the agreement of ST and the apnea–hypopnea index (AHI) calculated by the HSAT device and Soomirang. ST demonstrated a correlation of 0.9 with an average time difference of 7.5 min, while AHI showed a correlation of 0.95 with an average AHI difference of 3. The accuracy, sensitivity, and specificity of the Soomirang for detecting OSA were 97.14%, 100%, and 95.45% at AHI ≥ 15, respectively. The proposed algorithm, utilizing data from a wireless abdomen-worn device exhibited excellent performance in detecting moderate to evere OSA. The findings underscored the potential of a simple device as an accessible and effective tool for OSA screening and follow-up.