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Ryu, Ja-Hyoung
Supramolecular NanoMaterials Lab (SUN)
Research Interests
  • Supramolecular assembly, synthetic peptide assembly, cancer drug delivery

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Noncovalent Encapsulation Stabilities in Supramolecular Nanoassemblies

Cited 50 times inthomson ciCited 44 times inthomson ci
Title
Noncovalent Encapsulation Stabilities in Supramolecular Nanoassemblies
Author
Jiwpanich, SiripornRyu, Ja-HyoungBickerton, SeanThayumanavan, S.
Issue Date
2010-08
Publisher
AMER CHEMICAL SOC
Citation
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.132, no.31, pp.10683 - 10685
Abstract
Exchange dynamics of lipophilic guest molecules, encapsulated in supramolecular nanoassemblies in aqueous solutions, have implications in evaluating the stability of drug delivery vehicles. This is because exchange dynamics is related to the propensity of a nanocarrier to be leaky. We describe a fluorescence resonance energy transfer (FRET) based method to evaluate guest exchange dynamics in the aqueous phase. We have utilized this method to analyze the stability of encapsulation in polymeric nanogels and other related amphiphilic nanoassemblies.
URI
https://scholarworks.unist.ac.kr/handle/201301/8920
URL
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77955356559
DOI
10.1021/ja105059g
ISSN
0002-7863
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CHM_Journal Papers
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