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Rhee, Hyun-Woo
Biomimetic Chemistry Lab
Research Interests
  • Site-Specific Protein Labeling in Living Cells
  • Artificial Cofactors for Biomimetic Catalyst
  • Spatiotemporal Proteome mapping of living cells

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Focused Fluorescent Probe Library for Metal Cations and Biological Anions

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Title
Focused Fluorescent Probe Library for Metal Cations and Biological Anions
Author
Rhee, Hyun-WooLee, Sang WookLee, Jun-SeokChang, Young-TaeHong, Jong-In
Keywords
biological anions; fluorescent probe library; metal cations; thymidine
Issue Date
2013-09
Publisher
AMER CHEMICAL SOC
Citation
ACS COMBINATORIAL SCIENCE, v.15, no.9, pp.483 - 490
Abstract
A focused fluorescent probe library for metal cations was developed by combining metal chelators and picolinium/quinolinium moieties as combinatorial blocks connected through a styryl group. Furthermore, metal complexes derived from metal chelators having high binding affinities for metal cations were used to construct a focused probe library for phosphorylated biomolecules. More than 250 fluorescent probes were screened for identifying an ultraselective probe for dTTP.
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DOI
10.1021/co400034x
ISSN
2156-8952
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PHY_Journal Papers
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