A Polymersome Nanoreactor with Controllable Permeability Induced by Stimuli-Responsive Block Copolymers
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- A Polymersome Nanoreactor with Controllable Permeability Induced by Stimuli-Responsive Block Copolymers
- Kim, Kyoung Taek; Cornelissen, Jeroen J. L. M.; Nolte, Roeland J. M.; van Hest, Jan C. M.
- Amphiphilic block copolymers; Average diameter; Boronic acid; Membrane permeability; Polymersome; Polymersomes; Self-assembled; SIMPLE method; Spherical objects; Stimuli-responsive; TEM
- Issue Date
- WILEY-V C H VERLAG GMBH
- ADVANCED MATERIALS, v.21, no.27, pp.2787 - 2788
- A method to generate and control the permeability of polymersome membranes using mixtures of amphiphilic and stimuli-responsive boronic acid-containing block copolymers is reported. The latter block copolymers form phase-separated domains in the polymersomes, which can be dissolved by increasing the pH of the medium or by introducing sugar molecules that covalently bind to the boronic acid moieties.
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