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박철민

Park, Cheol-Min
Synthetic and Medicinal Chemistry Lab.
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dc.citation.endPage 415 -
dc.citation.number 1 -
dc.citation.startPage 413 -
dc.citation.title JOURNAL OF ORGANIC CHEMISTRY -
dc.citation.volume 71 -
dc.contributor.author Park, Cheol-Min -
dc.date.accessioned 2023-12-22T10:08:58Z -
dc.date.available 2023-12-22T10:08:58Z -
dc.date.created 2014-11-10 -
dc.date.issued 2006-01 -
dc.description.abstract The basicity of an amine has a great impact on physicochemical properties and pharmacokinetics. To attenuate the basicity of morpholine, a bicyclic amine was designed and synthesized with the introduction of an additional β-oxygen. A transannular cyclization and reduction of a bridgehead α-chloro amine functionality produces the topographically unusual amine (pKa = 6.7) in good yield. -
dc.identifier.bibliographicCitation JOURNAL OF ORGANIC CHEMISTRY, v.71, no.1, pp.413 - 415 -
dc.identifier.doi 10.1021/jo051982z -
dc.identifier.issn 0022-3263 -
dc.identifier.scopusid 2-s2.0-31144447125 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/8557 -
dc.identifier.url http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=31144447125 -
dc.identifier.wosid 000234438700064 -
dc.language 영어 -
dc.publisher AMER CHEMICAL SOC -
dc.title Concise synthesis of 3,7-dioxa-9-aza-bicyclo[3,3,1]-nonane -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.description.journalRegisteredClass scopus -
dc.subject.keywordPlus TRANSANNULAR CYCLIZATION -
dc.subject.keywordPlus AMINE BASICITY -

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