File Download
There are no files associated with this item.
SFX Link
- Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
- Park, Cheol-Min
- Synthetic and Medicinal Chemistry Lab.
Views & Downloads
Detailed Information
Cited time in 
Cited time in 
Cited time in
Metadata Downloads
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.citation.endPage | 7506 | - |
| dc.citation.number | 24 | - |
| dc.citation.startPage | 7503 | - |
| dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.citation.volume | 20 | - |
| dc.contributor.author | Bruncko, Milan | - |
| dc.contributor.author | Tahir, Stephen K. | - |
| dc.contributor.author | Song, Xiaohong | - |
| dc.contributor.author | Chen, Jun | - |
| dc.contributor.author | Ding, Hong | - |
| dc.contributor.author | Huth, Jeffrey R. | - |
| dc.contributor.author | Jin, Sha | - |
| dc.contributor.author | Judge, Russell A. | - |
| dc.contributor.author | Madar, David J. | - |
| dc.contributor.author | Park, Chang H. | - |
| dc.contributor.author | Park, Cheol-Min | - |
| dc.contributor.author | Petros, Andrew M. | - |
| dc.contributor.author | Tse, Christin | - |
| dc.contributor.author | Rosenberg, Saul H. | - |
| dc.contributor.author | Elmore, Steven W. | - |
| dc.date.accessioned | 2023-12-22T06:38:49Z | - |
| dc.date.available | 2023-12-22T06:38:49Z | - |
| dc.date.created | 2014-11-10 | - |
| dc.date.issued | 2010-12 | - |
| dc.description.abstract | We describe the development of a novel series of N-aryl-benzimidazolone HSP90 inhibitors (9) targeting the N-terminal ATP-ase site. SAR development was influenced by structure-based design based around X-ray structures of ligand bound HSP90 complexes. Lead compounds exhibited high binding affinities, ATP-ase inhibition and cellular client protein degradation. | - |
| dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.20, no.24, pp.7503 - 7506 | - |
| dc.identifier.doi | 10.1016/j.bmcl.2010.10.010 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.scopusid | 2-s2.0-78449271034 | - |
| dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/8540 | - |
| dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=78449271034 | - |
| dc.identifier.wosid | 000284332900070 | - |
| dc.language | 영어 | - |
| dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
| dc.title | N-Aryl-benzimidazolones as novel small molecule HSP90 inhibitors | - |
| dc.type | Article | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.