File Download

There are no files associated with this item.

  • Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
Related Researcher


Cha, Chaenyung
Integrative Biomaterials Engineering Lab.
Read More

Views & Downloads

Detailed Information

Cited time in webofscience Cited time in scopus
Metadata Downloads

Comprehensive Tuning of Bioadhesive Properties of Polydimethylsiloxane (PDMS) Membranes with Controlled Porosity

Jang, YeonseokLee, MinseokKim, HyojaeCha, ChaenyungJung, JinmuOh, Jonghyun
Issued Date
제20차 한국조직공학 재생의학회 학술대회
Please double check for any spelling mistakes. Polydimethylsiloxane (PDMS)-based elastomers have become the de facto platform for various biomedical applications. But the stable attachment of biomolecules to PDMS for more robust and long-term performance of the PDMS-based devices has been a significant challenge, owing to its unique physical properties (e.g. hydrophobicity, dynamic molecular mobility). Herein, the PDMS membrane with tunable surface porosity is developed via high-pressure saturated steam technology in order to promote a strong and lasting bioadhesion to the PDMS membrane without additional processing steps. The resulting porous PDMS membranes demonstrate enhanced physical properties (e.g. Young’s modulus, roughness, and air permeability), which is dependent on the membrane thickness. The bioactivity of porous PDMS membranes, evaluated by measuring the adhesion of various biomolecules and bioactivity of cells, shows significant improvement over conventional non-porous control. This effect can be attributed to the strong physical adsorption on the porous PDMS membrane by increased surface roughness and stiffness. In sum, the porous PDMS membrane provides a simple and yet highly effective platform to create bioactive surface for various biomedical devices.
한국조직공학 재생의학회


Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.