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Cha, Chaenyung
Integrative Biomaterials Engineering
Research Interests
  • Biopolymer, nanocomposites, microfabrication, tissue engineering, drug delivery

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"Living" Microvascular Stamp for Patterning of Functional Neovessels; Orchestrated Control of Matrix Property and Geometry

Cited 17 times inthomson ciCited 17 times inthomson ci
Title
"Living" Microvascular Stamp for Patterning of Functional Neovessels; Orchestrated Control of Matrix Property and Geometry
Author
Jeong, Jae HyunChan, VincentCha, ChaenyungZorlutuna, PinarDyck, CaseyHsia, K. JimmyBashir, RashidKong, Hyunjoon
Keywords
angiogenesis; cell-encapsulation; methacrylic alginate; patterned neovessels; stereolithography
Issue Date
2012-01
Publisher
WILEY-V C H VERLAG GMBH
Citation
ADVANCED MATERIALS, v.24, no.1, pp.58 -
Abstract
This study presents a "living" microvascular stamp that releases multiple angiogenic factors and subsequently creates functional neovessels with the same pattern as that engraved in the stamp. The stamp consists of live cells that secrete angiogenic factors, an engineered hydrogel matrix that promotes cellular expression of angiogenic factors, and a three-dimensional geometry that localizes the angiogenic factors within the pattern.
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DOI
10.1002/adma.201103207
ISSN
0935-9648
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MSE_Journal Papers
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