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Park, Jang-Ung
Flexible Nano-electronics & Biotechnology Lab
Research Interests
  • Wireless wearable electronics, flexible electronics, printed electronics, nano-bio interfaces

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Nanoscale Patterns of Oligonucleotides Formed by Electrohydrodynamic Jet Printing with Applications in Biosensing and Nanomaterials Assembly

Cited 71 times inthomson ciCited 66 times inthomson ci
Title
Nanoscale Patterns of Oligonucleotides Formed by Electrohydrodynamic Jet Printing with Applications in Biosensing and Nanomaterials Assembly
Author
Park, Jang-UngLee, Jung HeonPaik, UngyuLu, YiRogers, John A.
Keywords
Acoustic energies; Aptamer; Bio-sensing; Diverse materials; Dna inks; Electronic devices; High spatial resolutions; Jet printings; Key features; Nano-materials; Nano-scale patterns; Nanoparticle assemblies; Piezoelectric ink jets; Substrate types
Issue Date
2008-12
Publisher
AMER CHEMICAL SOC
Citation
NANO LETTERS, v.8, no.12, pp.4210 - 4216
Abstract
The widespread use of DNA in microarrays for applications in biotechnology, combined with its promise in programmed nanomaterials assembly, unusual electronic devices, and other areas has created interest in methods for patterning DNA with high spatial resolution. Techniques based on thermal or piezoelectric inkjet printing are attractive due to their noncontacting nature and their compatibility with diverse materials and substrate types; their modest resolution (i.e., 10-20 mu m) represents a major limitation for certain systems. Here we demonstrate the use of an operationally similar printing approach that exploits electrohydrodynamic forces, rather than thermal or acoustic energy, to eject DNA inks through fine nozzles, in a controlled fashion. This DNA printer is capable of resolution approaching 100 nm. A range of experiments on patterns of DNA formed with this printer demonstrates its key features. Example applications in DNA-directed nanoparticle assembly and DNA aptamer-based biosensing illustrate two representative uses of the patterns that can be formed.
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DOI
10.1021/nl801832v
ISSN
1530-6984
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MSE_Journal Papers
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