Optically-active defects in crystals can serve on-demand single photons and coherent spin qubits. Therefore, they provide important hardware for solid-state quantum architectures. However, limitation in optical interface and unwanted interaction in solid-state environment prevents efficient control and readout of the qubits states. Here, we present recent progress for high-resolution and high contrast optical interfaces for defect qubits as well as suppressed phonon interaction in point-planar defect complex in nanowire structures. Our approaches enable us to address defects with higher resolution and sensitivity, and therefore it will pave a new way of exploring solid-state quantum systems.