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TRAP1 binds to glutamine synthetase and might affect cancer cell metabolism.
- Author(s)
- Lim, Hakmyeong
- Advisor
- Kang, Byoung Heon
- Issued Date
- 2015-02
- URI
- https://scholarworks.unist.ac.kr/handle/201301/71909 http://unist.dcollection.net/jsp/common/DcLoOrgPer.jsp?sItemId=000001925169
- Abstract
- TRAP1 is anti-apoptotic mitochondrial protein. There have been implications about this chaperone and cancer cell metabolism but it is not known how TRAP1 affects. Glutamine synthetase is a candidate of TRAP1 binding protein in this study. GS is well known as ammonia detoxifying function. This paper will deal with 2 proteins’ binding and their role in cancer cell metabolism.
- Publisher
- Ulsan National Institute of Science and Technology (UNIST)
- Degree
- Master
- Major
- Department of Biological Sciences
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