Related Researcher

Author's Photo

Park, Chan Young
Calcium Dynamics Lab
Research Interests
  • Calcium Signaling, Calcium Channels, Immune, neuroscience, Drug Development, Virus and host cell interaction.


Arabidopsis ubiquitin-specific protease 6 (AtUBP6) interacts with calmodulin

DC Field Value Language Moon, BC ko Choi, MS ko Kang, YH ko Kim, MC ko Cheong, MS ko Park, Chan Young ko Yoo, JH ko Koo, SC ko Lee, SM ko Lim, CO ko Cho, Moo Je ko Chung, WS ko 2014-10-16T01:42:10Z - 2014-10-13 ko 2005-07 ko
dc.identifier.citation FEBS LETTERS, v.579, no.18, pp.3885 - 3890 ko
dc.identifier.issn 0014-5793 ko
dc.identifier.uri -
dc.description.abstract Calmodulin (CaM), a key Ca2+ sensor in eukaryotes, regulates diverse cellular processes by interacting with many proteins. To identify Ca2+/CaM-mediated signaling components, we screened an Arabidopsis expression library with horseradish peroxidase-conjugated Arabidopsis calmodulin2 (AtCaM2) and isolated a homolog of the UBP6 deubiquitinating enzyme family (AtUBP6) containing a Ca2+-dependent CaM-binding domain (CaMBD). The CaM-binding activity of the AtUBP6 CaMBD was confirmed by CaM mobility shift assay, phosphodiesterase competition assay and site-directed mutagenesis. Furthermore, expression of AtUBP6 restored canavanine resistance to the Delta ubp6 yeast mutant. This is the first demonstration that Ca2+ signaling via CaM is involved in ubiquitin-mediated protein degradation and/or stabilization in plants. ko
dc.description.statementofresponsibility close -
dc.language 영어 ko
dc.publisher ELSEVIER SCIENCE BV ko
dc.title Arabidopsis ubiquitin-specific protease 6 (AtUBP6) interacts with calmodulin ko
dc.type ARTICLE ko
dc.identifier.scopusid 2-s2.0-21844436532 ko
dc.identifier.wosid 000230687100004 ko
dc.type.rims ART ko
dc.description.wostc 8 *
dc.description.scopustc 9 * 2015-05-06 * 2014-10-13 *
dc.identifier.doi 10.1016/j.febslet.2005.05.080 ko
dc.identifier.url ko
Appears in Collections:
BIO_Journal Papers
Files in This Item:
There are no files associated with this item.

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show simple item record


  • mendeley


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.