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Park, Jiyoung
Molecular Metabolism Laboratory (MML)
Research Interests
  • Obesity, diabetes, adipose tissue, cancer, cancer-associated adipocyte, dermal adipocyte, metabolic memory

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Catechin gallates are NADP(+)-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP(+) as a coenzyme

DC Field Value Language
dc.contributor.author Shin, Eui Seok ko
dc.contributor.author Park, Jiyoung ko
dc.contributor.author Shin, Jae-Min ko
dc.contributor.author Cho, Dooho ko
dc.contributor.author Cho, Si Young ko
dc.contributor.author Shin, Dong Wook ko
dc.contributor.author Ham, Mira ko
dc.contributor.author Kim, Jae Bum ko
dc.contributor.author Lee, Tae Ryong ko
dc.date.available 2014-10-16T01:41:57Z -
dc.date.created 2014-10-13 ko
dc.date.issued 2008-04 ko
dc.identifier.citation BIOORGANIC & MEDICINAL CHEMISTRY, v.16, no.7, pp.3580 - 3586 ko
dc.identifier.issn 0968-0896 ko
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/7178 -
dc.description.abstract Recent studies have shown that glucose-6-phosphate dehydrogenase (G6PD) is an effectual therapeutic target for metabolic disorders, including obesity and diabetes. In this study, we used in silico and conventional screening approaches to identify putative inhibitors of G6PD and found that gallated catechins (EGCG, GCG, ECG, CG), but not ungallated catechins (ECG, GC, EC, C), were NADP+-competitive inhibitors of G6PD and other enzymes that employ NADP+ as a coenzyme, such as IDH and 6PGD. ko
dc.description.statementofresponsibility close -
dc.language 영어 ko
dc.publisher PERGAMON-ELSEVIER SCIENCE LTD ko
dc.title Catechin gallates are NADP(+)-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP(+) as a coenzyme ko
dc.type ARTICLE ko
dc.identifier.scopusid 2-s2.0-41649106850 ko
dc.identifier.wosid 000255245900010 ko
dc.type.rims ART ko
dc.description.wostc 16 *
dc.description.scopustc 18 *
dc.date.tcdate 2015-05-06 *
dc.date.scptcdate 2014-10-13 *
dc.identifier.doi 10.1016/j.bmc.2008.02.030 ko
dc.identifier.url http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=41649106850 ko
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