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Choi, Jang Hyun
Lab of Diabetes and Metabolism Lab.
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dc.citation.endPage 26629 -
dc.citation.number 38 -
dc.citation.startPage 26618 -
dc.citation.title JOURNAL OF BIOLOGICAL CHEMISTRY -
dc.citation.volume 289 -
dc.contributor.author Choi, Sun-Sil -
dc.contributor.author Kim, Eun Sun -
dc.contributor.author Koh, Minseob -
dc.contributor.author Lee, Soo-Jin -
dc.contributor.author Lim, Donghyun -
dc.contributor.author Yang, Yong Ryoul -
dc.contributor.author Jang, Hyun-Jun -
dc.contributor.author Seo, Kyung-ah -
dc.contributor.author Min, Sang-Hyun -
dc.contributor.author Lee, In Hee -
dc.contributor.author Park, Seung Bum -
dc.contributor.author Suh, Pann-Ghill -
dc.contributor.author Choi, Jang Hyun -
dc.date.accessioned 2023-12-22T02:13:07Z -
dc.date.available 2023-12-22T02:13:07Z -
dc.date.created 2014-10-06 -
dc.date.issued 2014-09 -
dc.description.abstract Background: PPARβ ligands can be used in numerous metabolic syndromes. Results: A novel non-agonist PPARβ ligand, UHC1 exhibited great beneficial effects on glucose metabolism and anti-inflammatory response. Conclusion: UHC1 shows anti-diabetic action by blocking CDK5-mediated PPARβ phosphorylation. Significance: UHC1 can be a novel therapeutic agent for use in type 2 diabetes and related metabolic disorders. -
dc.identifier.bibliographicCitation JOURNAL OF BIOLOGICAL CHEMISTRY, v.289, no.38, pp.26618 - 26629 -
dc.identifier.doi 10.1074/jbc.M114.566794 -
dc.identifier.issn 0021-9258 -
dc.identifier.scopusid 2-s2.0-84907203364 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/6901 -
dc.identifier.url http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84907203364 -
dc.identifier.wosid 000342128800052 -
dc.language 영어 -
dc.publisher AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC -
dc.title A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.relation.journalWebOfScienceCategory Biochemistry & Molecular Biology -
dc.relation.journalResearchArea Biochemistry & Molecular Biology -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -

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