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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 26629 | - |
dc.citation.number | 38 | - |
dc.citation.startPage | 26618 | - |
dc.citation.title | JOURNAL OF BIOLOGICAL CHEMISTRY | - |
dc.citation.volume | 289 | - |
dc.contributor.author | Choi, Sun-Sil | - |
dc.contributor.author | Kim, Eun Sun | - |
dc.contributor.author | Koh, Minseob | - |
dc.contributor.author | Lee, Soo-Jin | - |
dc.contributor.author | Lim, Donghyun | - |
dc.contributor.author | Yang, Yong Ryoul | - |
dc.contributor.author | Jang, Hyun-Jun | - |
dc.contributor.author | Seo, Kyung-ah | - |
dc.contributor.author | Min, Sang-Hyun | - |
dc.contributor.author | Lee, In Hee | - |
dc.contributor.author | Park, Seung Bum | - |
dc.contributor.author | Suh, Pann-Ghill | - |
dc.contributor.author | Choi, Jang Hyun | - |
dc.date.accessioned | 2023-12-22T02:13:07Z | - |
dc.date.available | 2023-12-22T02:13:07Z | - |
dc.date.created | 2014-10-06 | - |
dc.date.issued | 2014-09 | - |
dc.description.abstract | Background: PPARβ ligands can be used in numerous metabolic syndromes. Results: A novel non-agonist PPARβ ligand, UHC1 exhibited great beneficial effects on glucose metabolism and anti-inflammatory response. Conclusion: UHC1 shows anti-diabetic action by blocking CDK5-mediated PPARβ phosphorylation. Significance: UHC1 can be a novel therapeutic agent for use in type 2 diabetes and related metabolic disorders. | - |
dc.identifier.bibliographicCitation | JOURNAL OF BIOLOGICAL CHEMISTRY, v.289, no.38, pp.26618 - 26629 | - |
dc.identifier.doi | 10.1074/jbc.M114.566794 | - |
dc.identifier.issn | 0021-9258 | - |
dc.identifier.scopusid | 2-s2.0-84907203364 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/6901 | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84907203364 | - |
dc.identifier.wosid | 000342128800052 | - |
dc.language | 영어 | - |
dc.publisher | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | - |
dc.title | A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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