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Jang, Ji-Hyun
Nano Crystal Lab (NCL)
Research Interests
  • Graphene, photoelectrochemical (PEC) H2 generation, ORR/OER, SERS,3D-Nanostructures, supercapacitors, thermoelectric materials

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Three-dimensionally-patterned submicrometer-scale hydrogel/air networks that offer a new platform for biomedical applications

Cited 25 times inthomson ciCited 24 times inthomson ci
Title
Three-dimensionally-patterned submicrometer-scale hydrogel/air networks that offer a new platform for biomedical applications
Author
Jang, Ji-HyunJhaveri, Shalin J.Rasin, BorisKoh, ChoengYangOber, Christopher K.Thomas, Edwin L.
Keywords
Bicontinuous; Bio-medical applications; Direct access; Electrical couplings; High surface areas; Hydrogel structures; Hydroxy ethyl methacrylates; Interference lithographies; Methacrylic acids; Methyl methacrylates; Negative tones; Neural prosthetic; Neuronal growths; Neurotrophins; Ph-responsive; Phase masks; Sub micrometers; Three-dimensional (3D)
Issue Date
2008-05
Publisher
AMER CHEMICAL SOC
Citation
NANO LETTERS, v.8, no.5, pp.1456 - 1460
Abstract
Phase mask interference lithography was employed to fabricate three-dimensional (3D) hydrogel structures with high surface area on neural prosthetic devices. A random terpolymer of poly(hydroxyethyl methacrylate-ran-methyl methacrylate-ran-methacrylic acid) was synthesized and used as a negative-tone photoresist to generate bicontinuous 3D hydrogel structures at the submicrometer scale. We demonstrated that the fully open 3D hydrogel/air networks can be used as a pH-responsive polymeric drug-release system for the delivery of neurotrophins to enhance the performance of neural prosthetic devices. Additionally an open hydrogel structure will provide direct access of neuronal growth to the device for improved electrical coupling.
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DOI
10.1021/nl080444+
ISSN
1530-6984
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ECHE_Journal Papers
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