Brain Infraslow Activity Correlates With Arousal Levels

Abstract

The functional role of the brain’s infraslow activity (ISA, 0.01–0.1 Hz) in human behavior has yet to be elucidated. To date, it has been shown that the brain’s ISA correlates with behavioral performance; task performance is more likely to increase when executed at a specific ISA phase. However, it is unclear how the ISA correlates behavioral performance. We hypothesized that the ISA phase correlation of behavioral performance is mediated by arousal. Our data analysis results showed that the electroencephalogram (EEG) ISA phase was correlated with the galvanic skin response (GSR) amplitude, a measure of the arousal level. Furthermore, subjects whose EEG ISA phase correlated with the GSR amplitude more strongly also showed greater EEG ISA modulation during meditation, which implies an intimate relationship between brain ISA and arousal. These results may help improve understanding of the functional role of the brain’s ISA.